Prevention of Infection in Orthopedic Prosthetic Surgery.

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Abstract

[Indexed for MEDLINE] 18. J Am Board Fam Med. 2016 Jul-Aug;29(4):500-7. doi: 10.3122/jabfm.2016.04.150386. Antibiotic Prophylaxis for Patients with a History of Total Joint Replacement. DeFroda SF(1), Lamin E(2), Gil JA(2), Sindhu K(2), Ritterman S(2). Author information: (1)From the Department of Orthopaedics, Alpert Medical School, Brown University, Providence, RI (SFD, JAG, SR); the Department of Urology, University of Pennsylvania, Perelman Center for Advanced Medicine, Philadelphia (EL); and Department of Orthopaedics Alpert Medical School of Brown University, 593 Eddy Street, Providence, RI 02903 (KS). sdefroda@gmail.com. (2)From the Department of Orthopaedics, Alpert Medical School, Brown University, Providence, RI (SFD, JAG, SR); the Department of Urology, University of Pennsylvania, Perelman Center for Advanced Medicine, Philadelphia (EL); and Department of Orthopaedics Alpert Medical School of Brown University, 593 Eddy Street, Providence, RI 02903 (KS). As the population ages and people remain active into the 7th and 8th decades of life, the frequency of total joint replacement is increasing. Following joint replacement surgery, patients inevitably require various invasive procedures as part of their routine health maintenance, including, but not limited to, dental care, colonoscopy, cystoscopy, and cardiac catheterization. There is scant evidence to support the use of periprocedural prophylactic antibiotics in the prevention of late total joint infection. The guidelines for the usage of periprocedural antibiotics have changed as knowledge of the pathophysiology of joint infection has evolved. We review the current recommendations from subspecialty academic organizations regarding antibiotic prophylaxis for patients undergoing routine urologic, gastrointestinal, dental, and cardiac procedures after total joint replacement. © Copyright 2016 by the American Board of Family Medicine. DOI: 10.3122/jabfm.2016.04.150386