Single-case metanalysis of fat embolism syndrome.

Journal and index pages often block iframe embedding. This reader keeps the evidence details in Orthonotes and leaves the source page one click away.

Abstract

[Indexed for MEDLINE] 6. Anaesthesia. 2001 Feb;56(2):145-54. doi: 10.1046/j.1365-2044.2001.01724.x. Fat embolism. Mellor A(1), Soni N. Author information: (1)Chelsea and Westminster Hospital, Fulham Road, London SW10 9NH, UK. Comment in Anaesthesia. 2001 Jul;56(7):692-3. doi: 10.1046/j.1365-2044.2001.02137-5.x. Fat embolism syndrome is a collection of respiratory, haematological, neurological and cutaneous symptoms and signs associated with trauma and other disparate surgical and medical conditions. The incidence of the clinical syndrome is low (< 1% in retrospective reviews) whilst the embolisation of marrow fat appears to be an almost inevitable consequence of long bone fractures. There is debate over the pathogenesis of fat embolism syndrome and it seems a variety of factors interact to produce a spectrum of end organ damage. Many therapeutic interventions and prophylactic strategies have been tried with varying success. Current treatments are supportive and the condition is usually associated with a good outcome. The literature on fat embolism syndrome is extensive and this review aims to discuss the incidence, aetiology, pathophysiology, diagnosis and treatment of fat embolism. DOI: 10.1046/j.1365-2044.2001.01724.x