Foot and ankle clinics | 2019 | Dederer KM, Tennant JN
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[Indexed for MEDLINE] 11. J Clin Med. 2022 Jun 27;11(13):3698. doi: 10.3390/jcm11133698. Achilles Tendon Rupture and Dysmetabolic Diseases: A Multicentric, Epidemiologic Study. Oliva F(1), Marsilio E(1), Asparago G(1), Giai Via A(2), Biz C(3), Padulo J(4), Spoliti M(5), Foti C(6), Oliva G(7), Mannarini S(8)(9), Rossi AA(8)(9), Ruggieri P(3), Maffulli N(1)(10)(11). Author information: (1)Department of Medicine, Surgery and Dentistry, University of Salerno, Via S. Allende, 84081 Baronissi, Italy. (2)Department of Orthopaedic Surgery and Traumatology, San Camillo-Forlanini Hospital, 00152 Rome, Italy. (3)Orthopaedics and Orthopaedic Oncology, Department of Surgery, Oncology and Gastroenterology DiSCOG, University of Padua, 35128 Padova, Italy. (4)Department of Biomedical Sciences for Health, Università degli Studi di Milano, 20133 Milan, Italy. (5)Orthopaedics and Traumatology Unit, Department of Emergency and Acceptance, Azienda Ospedaliera San Camillo-Forlanini, 00152 Rome, Italy. (6)Physical and Rehabilitation Medicine, Clinical Sciences and Translational Medicine Department, Tor Vergata University, 00133 Rome, Italy. (7)Department of Internal Medicine, Ospedale del Mare, ASL1, 80147 Napoli, Italy. (8)Department of Philosophy, Sociology, Education, and Applied Psychology, Section of Applied Psychology, University of Padova, 35128 Padova, Italy. (9)Interdepartmental Center for Family Research, University of Padova, 35128 Padova, Italy. (10)School of Pharmacy and Bioengineering, Keele University Faculty of Medicine, Thornburrow Drive, Stoke on Trent ST4 7QB, UK. (11)Centre for Sports and Exercise Medicine, Barts and the London School of Medicine and Dentistry, Mile End Hospital, Queen Mary University of London, 275 Bancroft Road, London E1 4DG, UK. Introduction: Achilles tendon ruptures are common. Metabolic disorders, such as diabetes mellitus, hypercholesterolemia, thyroid disorders, and obesity, impair tendons health, leading to Achilles tendinopathy and likely predisposing patients to Achilles tendon ruptures. Materials and methods: Patients who visited the Orthopedic Outpatient Clinics and the Accident and Emergency Departments of five different hospitals in Italy were recruited. Through telephone interviews, we administered a questionnaire to all the patients who had undergone surgical ATR repair, evaluating their past medical history, sport- and work-related activities, drug use, and post-operative rehabilitation outcomes. Results: "Return to work activities/sport" was negatively predicted by the presence of a metabolic disorder (β = -0.451; OR = 0.637) and 'open' surgery technique (β = -0.389; OR = 0.678). "Medical complications" were significantly predicted by metabolic disorders (β = 0.600 (0.198); OR = 1.822) and was negatively related to 'mini-invasive' surgery (i.e., not 'open' nor 'percutaneous') (β = -0.621; OR = 0.537). "Immediate weightbearing" and "immediate walking without assistance" were negatively predicted by 'open' technique (β = -0.691; OR = 0.501 and β = -0.359 (0.174; OR = 0.698)). Conclusions: Metabolic conditions can strongly affect post-operative outcomes following surgical repair of acute Achilles tendon tears. DOI: 10.3390/jcm11133698 PMCID: PMC9267833
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