Optimizing Antibiotic Therapy in Musculoskeletal Infections.

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Abstract

[Indexed for MEDLINE] 3. Infect Dis Clin North Am. 2017 Jun;31(2):237-252. doi: 10.1016/j.idc.2017.01.009. Epub 2017 Mar 30. Management of Prosthetic Joint Infection. Tande AJ(1), Gomez-Urena EO(2), Berbari EF(2), Osmon DR(2). Author information: (1)Division of Infectious Diseases, Department of Internal Medicine, Mayo Clinic, 200 1st Street Southwest, Rochester, MN 55905, USA. Electronic address: tande.aaron@mayo.edu. (2)Division of Infectious Diseases, Department of Internal Medicine, Mayo Clinic, 200 1st Street Southwest, Rochester, MN 55905, USA. Although uncommon, prosthetic joint infection is a devastating complication. This challenging condition requires a coordinated management approach to achieve good patient outcomes. This review details the general principles to consider when managing patients with prosthetic joint infection. The different medical/surgical treatment strategies and how to appropriately select a strategy are discussed. The data to support each strategy are presented, along with discussion of antimicrobial strategies in specific situations. Copyright © 2017 Elsevier Inc. All rights reserved. DOI: 10.1016/j.idc.2017.01.009