Orthonotes
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PubMed Narrative Review Evidence Moderate

Optimizing Antibiotic Therapy in Musculoskeletal Infections.

Infectious disease clinics of North America | 2025 | Cortés-Penfield NW, Justo JA, McCreary EK, Ryder JH

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Source
PubMed
Type
Narrative Review
Evidence
Moderate

Abstract

[Indexed for MEDLINE] 3. Int Orthop. 2025 Jun;49(6):1309-1317. doi: 10.1007/s00264-025-06513-4. Epub 2025 Apr 4. Body mass index matters: morbid obese patients have different microorganism profiles in the setting of periprosthetic hip joint infections. Budin M(1)(2), Sandiford NA(3), Gehrke T(1), Citak M(4). Author information: (1)Helios Endo-Klinik Hamburg, Hamburg, Germany. (2)Department of Orthopaedics and Trauma, Medical University of Graz, Auenbruggerplatz 5, 8036, Graz, Austria. (3)University of Otago, Dunedin, New Zealand. (4)Helios Endo-Klinik Hamburg, Hamburg, Germany. mcitak@gmx.de. PURPOSE: This study investigated the relationship between BMI and microorganism profiles, with a particular focus on gut microorganisms in patients with PJI following total hip arthroplasty (THA). It also explored comorbidities, that may contribute to these variations. METHODS: This study included all patients treated at our institution for a PJI of a THA between 1996 and 2021. Patients were categorized into four distinct BMI groups:

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