New Therapeutic Vistas In Carpal Tunnel Syndrome Management Hands of Liberation Breaking the Bonds of Entrapment Neuropathy

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Abstract

Carpal tunnel syndrome CTS represents the most common entrapment neuropathy affecting approximately 8 percente of the adult population worldwide. This review examines the pathophysiological mechanisms of CTS and provides a critical evaluation of contemporary interventional approaches that bridge the gap between conservative treatment and surgical management. Particular emphasis is placed on emerging techniques such as ultrasound guided hydrodissection HD prolotherapy platelet rich plasma and hyaluronic acid injections. A systematic analysis of randomised controlled trials and meta analyses was conducted to evaluate the efficacy safety and long term outcomes of these interventions. The evidence suggests that ultrasound guided techniques offer significant advantages over blind injections with dextrose prolotherapy and platelet rich plasma demonstrating promising results for long term symptom management. This review provides clinicians with evidence based recommendations for the appropriate selection of interventional techniques based on disease severity and patient specific factors potentially reducing the need for surgical intervention in selected patients.