Evidence-based guidelines on orthobiologics.

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Abstract

Conflict of interest statement: The authors declare that they have no conflicts of interest in the authorship and publication of this contribution. 7. Curr Rev Musculoskelet Med. 2018 Dec;11(4):616-623. doi: 10.1007/s12178-018-9522-z. Platelet-rich plasma in the foot and ankle. Henning PR(1), Grear BJ(2). Author information: (1)Campbell Clinic Department of Orthopaedic Surgery & Biomedical Engineering, University of Tennessee, 1400 S. Germantown Rd, Germantown, 38138, TN, USA. (2)Campbell Clinic Department of Orthopaedic Surgery & Biomedical Engineering, University of Tennessee, 1400 S. Germantown Rd, Germantown, 38138, TN, USA. bgrear@campbellclinic.com. PURPOSE OF REVIEW: Platelet-rich plasma has become an increasingly popular treatment option within the orthopedic community to biologically enhance and stimulate difficult-to-heal musculoskeletal tissues. This review evaluates the recent literature on platelet-rich plasma use in the treatment of foot and ankle pathologies. RECENT FINDINGS: Recent literature has demonstrated platelet-rich plasma to have a possible benefit in the treatment of Achilles pathology, chronic plantar fasciitis, osteochondral lesions of the talus, ankle osteoarthritis, and diabetic foot ulcers. However, given the lack of standardization of platelet-rich plasma preparations and protocols and the predominance of low-quality studies, no definitive treatment indications exist. Platelet-rich plasma is a promising treatment option, but at present, there is only limited clinical evidence supporting its use in foot and ankle applications. DOI: 10.1007/s12178-018-9522-z PMCID: PMC6220005