Ultrasound-Guided Injection of Autologous Platelet-Rich Plasma for Refractory Lateral Epicondylitis of Humerus: Case Series.

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Abstract

Conflict of interest statement: The authors declare no conflict of interest. 9. Clin J Sport Med. 2013 Nov;23(6):502-3. doi: 10.1097/JSM.0000000000000042. How effective are injection treatments for lateral epicondylitis? Shiple BJ(1). Author information: (1)Department of Family and Community Medicine Temple University School of Medicine Philadelphia, Pennsylvania. Comment on Am J Sports Med. 2013 Mar;41(3):625-35. doi: 10.1177/0363546512472975. OBJECTIVE: To compare the effectiveness, after 3 months, of a single injection of platelet-rich plasma (PRP), glucocorticoid (GC), or saline in reducing pain in lateral epicondylitis. DESIGN: Randomized, controlled, 3-group trial (RCT). Patients and outcome assessors were blinded to intervention group. Sample size was calculated to show a clinically important difference in patient-reported pain intensity at 12 months with 17 patients per group. SETTING: Tertiary study at the Rheumatology Unit at the Diagnostic Centre of the Region Hospital Silkeborg, Denmark. PARTICIPANTS: Patients were referred to the Rheumatology Unit by general practitioners or other rheumatology or orthopedic departments. Inclusion criteria (verified by 1 physician) were lateral epicondylitis symptoms for ≥3 months (pain on the lateral side of the elbow and at the lateral epicondyle on palpation and during resisted dorsiflexion of the wrist), an ultrasound (US) color Doppler flow of ≥ grade 2 (range, 0-4). Exclusion criteria were age