How effective are injection treatments for lateral epicondylitis?

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Abstract

[Indexed for MEDLINE] 10. Knee Surg Sports Traumatol Arthrosc. 2022 Apr;30(4):1152-1160. doi: 10.1007/s00167-021-06541-8. Epub 2021 Apr 22. Cell-based therapy of the elbow: evidence for lateral tendinopathy-a review on current treatments. Greiner S(1)(2), Lawton R(3), Voss A(3)(4). Author information: (1)Sporthopaedicum Regensburg, Hildegrad-von-Bingen-Str. 1, 93053, Regensburg, Germany. greiner@sporthopaedicum.de. (2)Department of Trauma Surgery, University Medical Center Regensburg, Regensburg, Germany. greiner@sporthopaedicum.de. (3)Sporthopaedicum Regensburg, Hildegrad-von-Bingen-Str. 1, 93053, Regensburg, Germany. (4)Department of Trauma Surgery, University Medical Center Regensburg, Regensburg, Germany. PURPOSE: Cell-based therapies are on the rise in treating intra and extraarticular pathologies, trying to avoid surgical intervention and support local repair processes. Therefore, the aim was to summarize current evidence-based treatment options for a cell-based therapy around the elbow. METHODS: Through a literature review up-to date treatment algorithms and therapies have been identified and have been rated according to their evidence level for clinical recommendation. RESULTS: Regarding the four extraarticular anatomical regions of the elbow (anterior, medial, posterior and lateral) and the joint itself, the lateral elbow and its´ tendinopathies as well as the use of cell-based treatment options have been extensively studied and, therefore, allow for clear and evidence-based recommendations. The remaining three regions as wells as the intraarticular application do not show enough evidence for a clinical recommendation. CONCLUSION: In conclusion the cell-based approach for treating elbow pathologies can only be recommended for the lateral elbow, as there has been shown sufficient evidence for the extraarticular application. It has to be mentioned, that the results from the lateral elbow maybe transferred to other extra-articular tendinopathies, as the lack of evidence may be due to the rare appearance of posterior, medial and anterior tendon affection. No recommendation can be given for intra-articular use. LEVEL OF EVIDENCE: IV. © 2021. European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA). DOI: 10.1007/s00167-021-06541-8