The Journal of orthopaedic and sports physical therapy | 2014 | Martin RL, Davenport TE, Reischl SF, McPoil TG
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[Indexed for MEDLINE] 8. Blood Transfus. 2023 Mar;21(2):119-136. doi: 10.2450/2022.0087-22. Epub 2022 Oct 17. Ultrasound-guided injection of platelet-rich plasma for tendinopathies: a systematic review and meta-analysis. Masiello F(1), Pati I(1), Veropalumbo E(1), Pupella S(1), Cruciani M(1), De Angelis V(1). Author information: (1)Italian National Blood Centre, National Institute of Health, Rome, Italy. BACKGROUND: In this systematic review and meta-analysis, we evaluated ultrasound (US)-guided injections of platelet-rich plasma (PRP) as conservative treatment of tendinopathies. MATERIALS AND METHODS: We searched MEDLINE, EMBASE, SCOPUS, OVID, and the Cochrane Library to identify randomized controlled trials (RCT) on the use of US-guided PRP for tendinopathies. RESULTS: We found 33 RCT (2,025 subjects) that met our inclusion criteria: 8 in lateral epicondylitis, 5 in plantar fasciitis, 5 in Achilles tendinopathy, 7 in rotator cuff tendinopathy, 3 in patellar tendinopathy and 5 in carpal tunnel syndrome. PRP, given as a single injection (20 trials) or multiple injections (13 trials), was compared to US-guided injection of steroids, saline, autologous whole blood, local anesthetic, dry needling, prolotherapy, bone marrow mesenchymal stem cells, or with non-injective interventions. The outcomes more commonly reported included pain and functional measures, subgrouped as in the short-term (
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