Pediatric clinics of North America | 2020 | DePaola K, Cuddihy LA
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[Indexed for MEDLINE] 10. Vet Clin North Am Equine Pract. 2020 Aug;36(2):289-301. doi: 10.1016/j.cveq.2020.03.008. Epub 2020 Jun 11. Genetics of Equine Orthopedic Disease. Metzger J(1), Distl O(2). Author information: (1)Institute for Animal Breeding and Genetics, University of Veterinary Medicine Hannover, Buenteweg 17p, Hannover 30559, Germany. Electronic address: Julia.metzger@tiho-hannover.de. (2)Institute for Animal Breeding and Genetics, University of Veterinary Medicine Hannover, Buenteweg 17p, Hannover 30559, Germany. Orthopedic diseases are a common cause for limited exercise capacity in the horse. They often underlie genetic risk factors, which can affect bone, articular cartilage, tendons, ligaments, and adnexal structures among others. The genetic effects can directly interfere with tissue development and skeletal growth or can trigger degenerative or inflammatory processes. Many of these diseases of the locomotor system like osteochondrosis are complex and can be affected by multifactorial influences. For this reason, it is important for those performing diagnostic procedures to have a comprehensive knowledge of orthopedic diseases, their prevalence within breeds, and genetic background. Copyright © 2020 Elsevier Inc. All rights reserved. DOI: 10.1016/j.cveq.2020.03.008
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