Enchondroma of the Hand: Evaluation and Management.

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Abstract

[Indexed for MEDLINE] 18. Int J Surg Pathol. 2024 Feb;32(1):201-205. doi: 10.1177/10668969231173379. Epub 2023 May 4. Rare Dedifferentiated Periosteal Chondrosarcoma with 11-Year Metastatic Relapse: A Case Report. Gasparro MA(1), Lee L(1), Vijayakumar G(1), Gusho CA(1), Colman MW(1), Gitelis S(1), Miller I(1)(2), Blank AT(1). Author information: (1)Department of Orthopedic Surgery, Division of Oncology, Rush University Medical Center, Chicago, IL, USA. (2)Department of Pathology, Rush University Medical Center, Chicago, IL, USA. A 50-year-old man presented for evaluation of a periscapular mass. Biopsy suggested a low-grade chondrosarcoma; however, the resected specimen revealed a grade 2 chondrosarcoma with a low-grade dedifferentiated mesenchymal component. The mass multiply recurred as chondrosarcoma without a dedifferentiated component before the patient developed lung metastases of chondrosarcoma without a dedifferentiated component 11 years after the initial diagnosis and died of disease. This is one of the first reported cases of a dedifferentiated chondrosarcoma with low-grade dedifferentiated component. While overall prognosis may be better than in typical dedifferentiated chondrosarcoma, this tumor demonstrated numerous local recurrences as well as metastasis. DOI: 10.1177/10668969231173379