Prevention of fracture-related infection: a multidisciplinary care package.

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Abstract

[Indexed for MEDLINE] 15. Injury. 2018 Jun;49 Suppl 1:S83-S90. doi: 10.1016/S0020-1383(18)30310-3. Diagnostic challenges and future perspectives in fracture-related infection. Morgenstern M(1), Kühl R(2), Eckardt H(3), Acklin Y(3), Stanic B(4), Garcia M(5), Baumhoer D(6), Metsemakers WJ(7). Author information: (1)Department of Orthopedic Surgery and Traumatology, University Hospital Basel, Switzerland. Electronic address: morgenstern.mario@gmail.com. (2)Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Switzerland. (3)Department of Orthopedic Surgery and Traumatology, University Hospital Basel, Switzerland. (4)Musculoskeletal Infection Group, AO Research Institute Davos, Switzerland. (5)Department of Radiology, University Hospital Basel, Switzerland. (6)Bone Tumour Reference Centre at the Institute of Pathology, University Hospital and University of Basel, Switzerland. (7)Department of Trauma Surgery, University Hospitals Leuven, Belgium. Fracture-related infection (FRI) is one of the most challenging complications in orthopaedic trauma surgery. It has severe consequences for patients and an important socio-economic impact. FRI has distinct properties and needs to be addressed interdisciplinary. Since criteria for the diagnosis of FRI are not standardized, an expert panel recently proposed a definition for FRI. In this review the current diagnostic modalities and an interdisciplinary diagnostic algorithm based on this recently published definition, are presented and future diagnostic techniques discussed. Since to date, there is no single universal diagnostic test available that gives the clinician the definitive diagnosis of FRI, it is mandatory to follow a standardized diagnostic algorithm to correctly diagnose FRI. © 2018 Elsevier Ltd. All rights reserved. DOI: 10.1016/S0020-1383(18)30310-3