Contemporary surgical management of osteosarcoma and Ewing sarcoma.

Journal and index pages often block iframe embedding. This reader keeps the evidence details in Orthonotes and leaves the source page one click away.

Abstract

[Indexed for MEDLINE] 12. Injury. 2008 Apr;39(4):395-403. doi: 10.1016/j.injury.2007.07.018. Epub 2007 Dec 3. Pathological fractures in primary bone sarcomas. Papagelopoulos PJ(1), Mavrogenis AF, Savvidou OD, Benetos IS, Galanis EC, Soucacos PN. Author information: (1)First Department of Orthopaedics, Athens University Medical School, Athens, Greece. pjp@hol.gr Pathological fractures in patients with primary bone sarcomas should not be considered an absolute indication for amputation. Initial fracture management should include cast immobilisation or external fixation avoiding tumour-cell dissemination. The extent of fracture displacement and the type of fracture stabilisation may affect the outcome of patients with primary bone sarcomas presenting with pathological fractures. Patients with high-grade primary bone sarcomas should be treated by neo-adjuvant chemotherapy, and limb-salvage surgery. Pathological fractures in chemo-resistant primary bone sarcomas are a relative contraindication for limb salvage surgery. DOI: 10.1016/j.injury.2007.07.018