Endothelial cell-derived exosomes trigger a positive feedback loop in osteogenesis-angiogenesis coupling via up-regulating zinc finger and BTB domain containing 16 in bone marrow mesenchymal stem cell.

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Abstract

[Indexed for MEDLINE] Conflict of interest statement: Declarations Ethics approval and consent to participate Obtaining samples of hBMSCs was reviewed and approved by Ethics Committee of the First Hospital of Jilin University (No. 22K095-002). The animal experiment was reviewed and approved by the Animal Protection and Utilization Committee of Changchun Weishi Testing Technology Service (No. 20230109-01). Consent for publication All authors agree to be published. Conflict of interest The authors declare no competing interests. 20. J Hand Surg Eur Vol. 2024 Sep;49(8):1023-1029. doi: 10.1177/17531934231214103. Epub 2023 Nov 21. Paediatric trigger fingers: a 47-year experience. Wan R(1), Sarcon AK(2), Pommer PP(3)(4), Mundell BF(2), Zhao C(1), Moran SL(1)(3). Author information: (1)Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA. (2)Department of Surgery, Mayo Clinic, Rochester, MN, USA. (3)Division of Plastic Surgery, Department of Surgery, Mayo Clinic, Rochester, MN, USA. (4)Department of Orthopedic Surgery, Pontificia Universidad Católica de Chile, Santiago, Chile. Paediatric trigger finger is rare compared to adult trigger finger or paediatric trigger thumb, and the aetiology is unclear. Proposed causes include local trauma, anatomical anomalies and systemic conditions. The aim of the present study was to detail the anatomical causes of surgically treated paediatric trigger fingers and provide an operative algorithm based on the anatomical findings. A total of 76 trigger fingers in 38 patients were identified retrospectively at our institution between 1975 and 2022. In total, 41 fingers in 26 patients had anatomical variations. A nodular thickening on the tendon, similar to Notta's nodule in trigger thumbs, was the most common anatomical cause. Abnormal decussation of the flexor digitorum superficialis tendon was the second most common variation. The recurrence rate was significantly lower after resection of one slip of the flexor digitorum superficialis tendon compared to other surgical techniques in these patients. We recommend that surgeons assess for possible anatomical variation during surgery for the trigger finger.Level of evidence: IV. DOI: 10.1177/17531934231214103