The presence of 3D printing in orthopedics: A clinical and material review.

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Abstract

[Indexed for MEDLINE] 11. Biomaterials. 2019 Oct;219:119366. doi: 10.1016/j.biomaterials.2019.119366. Epub 2019 Jul 15. Bioinspired surface modification of orthopedic implants for bone tissue engineering. Hu C(1), Ashok D(1), Nisbet DR(1), Gautam V(2). Author information: (1)Research School of Engineering, Australian National University, ACT, 2601, Australia. (2)John Curtin School of Medical Research, Australian National University, ACT, 2601, Australia. Electronic address: vini.gautam@anu.edu.au. Biomedical implants have been widely used in various orthopedic treatments, including total hip arthroplasty, joint arthrodesis, fracture fixation, non-union, dental repair, etc. The modern research and development of orthopedic implants have gradually shifted from traditional mechanical support to a bioactive graft in order to endow them with better osteoinduction and osteoconduction. Inspired by structural and mechanical properties of natural bone, this review provides a panorama of current biological surface modifications for facilitating the interaction between medical implants and bone tissue and gives a future outlook for fabricating the next-generation multifunctional and smart implants by systematically biomimicking the physiological processes involved in formation and functioning of bones. Copyright © 2019 Elsevier Ltd. All rights reserved. DOI: 10.1016/j.biomaterials.2019.119366