Long-Term Outcomes of Osteochondral Allograft with Osteogenic Protein-1 Augmentation: A Twelve-Year Follow-Up.

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Abstract

Conflict of interest statement: The authors have no financial or proprietary interest in the subject matter of this article. 7. Am J Sports Med. 2011 Jul;39(7):1487-93. doi: 10.1177/0363546510397726. Epub 2011 Mar 3. Osteochondral transplantation of the talus: long-term clinical and magnetic resonance imaging evaluation. Imhoff AB(1), Paul J, Ottinger B, Wörtler K, Lämmle L, Spang J, Hinterwimmer S. Author information: (1)Department of Orthopedic Sports Medicine, Technical University, Munich, Germany. a.imhoff@sportortho.de BACKGROUND: Osteochondral lesions of the ankle are a common injury after ankle sprains, especially in young and active patients. The Osteochondral Autograft Transfer System (OATS) is the only 1-step surgical technique designed to replace the entire osteochondral unit. PURPOSE: This study was conducted to evaluate the long-term clinical and radiographic outcomes of the OATS procedure for the talus and compare the results of patients who have had prior surgical interventions with patients for whom OATS represents the primary surgical treatment. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: The authors retrospectively analyzed 26 talus OATS procedures (25 patients) with an average follow-up of 84 months (range, 53-124 months); 9 patients had OATS as a second surgical intervention. The patients completed the American Orthopaedic Foot & Ankle Society (AOFAS) and Tegner scores plus the visual analog scale (VAS) preoperatively and at follow-up. Magnetic resonance imaging examinations were conducted on a 1.5-T whole-body magnet that assessed transplant congruency, adjacent surface of the talus, the corresponding distal tibia, and joint effusion. RESULTS: The authors found significant increases for the AOFAS score (50 to 78 points, P < .01) and the Tegner score (3.1 to 3.7, P < .05) and a significant decrease for the VAS (7.8 to 1.5, P < .01) from preoperative to postoperative. Patients with normal integration or minor incongruity of the transplant on magnetic resonance imaging (81%) had significantly better AOFAS scores (P = .03). Other magnetic resonance imaging criteria did not predict clinical results. Patients for whom OATS represented a second procedure had significantly worse clinical AOFAS and Tegner scores plus a higher VAS. CONCLUSION: Long-term clinical and magnetic resonance imaging results after osteochondral transplantation are good and patients significantly benefit from this surgery. Magnetic resonance imaging should not be a routine control but appears to be indicated when clinical symptoms persist after osteochondral transplantation. DOI: 10.1177/0363546510397726