Malignant Bone-Forming Neoplasm With NIPBL::BEND2 Fusion.

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Abstract

[Indexed for MEDLINE] 5. Hematol Oncol Clin North Am. 2020 Feb;34(1):177-188. doi: 10.1016/j.hoc.2019.09.002. Epub 2019 Oct 28. Bone Sarcomas and Desmoids. Brownstein JM(1), DeLaney TF(2). Author information: (1)Francis H. Burr Proton Beam Therapy Center, Massachusetts General Hospital, 30 Fruit Street, Boston, MA 02114, USA; Department of Radiation Oncology, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA. (2)Department of Radiation Oncology, Harvard Medical School, Francis H. Burr Proton Therapy Center, Massachusetts General Hospital, 30 Fruit Street, Boston, MA 02114, USA. Electronic address: tdelaney@partners.org. Bone sarcomas are rare tumors arising in bone, representing only a small fraction of solid malignant tumors. Desmoids are benign, infiltrative soft tissue neoplasms. Because of their scarcity and a paucity of data, the management of these tumors can be challenging, especially for clinicians who infrequently encounter these tumors. This article reviews the current literature regarding the diagnosis, work-up, and treatment of these uncommon mesenchymal tumors. Copyright © 2019 Elsevier Inc. All rights reserved. DOI: 10.1016/j.hoc.2019.09.002