Osteoblastic Solitary Plasmacytoma of Bone.

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Abstract

[Indexed for MEDLINE] Conflict of interest statement: Conflict of Interest: The authors of this paper have no conflicts of interest, including specific financial interests, relationships, and/or affiliations relevant to the subject matter or materials included. 6. Neuroradiol J. 2014 Sep;27(4):431-7. doi: 10.15274/NRJ-2014-10078. Epub 2014 Aug 29. Neuroimaging of plasmacytoma. A pictorial review. Agarwal A(1). Author information: (1)Department Neuroradiology, University of Missouri-Columbia; Columbia, MO, USA - draajay@gmail.com. This pictorial review describes the spectrum of CT/MR imaging findings of solitary extramedullary and bone plasmacytomas in different locations related to neuroradiology. Plasmacytoma is considered a counterpart of multiple myeloma that is described as a solitary and discrete mass of monoclonal neoplastic plasma cells. It may arise from osseous (medullary) or extramedullary sites. Isolated extramedullary plasmacytoma is very rare and comprises less than 4% of all plasma cellular diseases of which more than 80% are localized to the submucosal lymphoid tissue of the nasopharynx, nasal cavity and paranasal sinuses. We will demonstrate imaging findings in ten histopathologically proven plasmacytomas in different locations related to neuroradiology. Extramedullary and osseous plasmacytoma show nonspecific CT and MR imaging findings. MR is the preferred modality for evaluation due to better soft tissue contrast. Features that may suggest the diagnosis of plasmacytoma are bulky soft tissue mass and relatively isointense signal on T2-weighted MR images due to high cellularity. DOI: 10.15274/NRJ-2014-10078 PMCID: PMC4236876