Open pelvic fracture: the killing fracture?

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Abstract

[Indexed for MEDLINE] Conflict of interest statement: ETHICS APPROVAL AND CONSENT TO PARTICIPATE: The abovementioned study was reviewed by the medical ethical committee of the Radboudumc and did not fall within the remit of the Medical Research Involving Human Subjects Act. COMPETING INTERESTS: The authors declare that they have no competing interests. PUBLISHER’S NOTE: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. 3. J Orthop Surg Res. 2020 Sep 3;15(1):377. doi: 10.1186/s13018-020-01904-2. Prevalence and influencing factors of nonunion in patients with tibial fracture: systematic review and meta-analysis. Tian R(1), Zheng F(1)(2), Zhao W(1)(3), Zhang Y(4), Yuan J(4), Zhang B(1), Li L(5). Author information: (1)Department of Orthopaedics, No.1 Hospital of China Medical University, Shenyang, China. (2)Department of Orthopaedics, Shenyang Orthopaedic Hospital, Shenyang, China. (3)Department of Orthopaedics, No.4 Hospital of China Medical University, Guangzhou, China. (4)Department of Dermatology, No.1 Hospital of China Medical University, Guangzhou, China. (5)Department of Orthopaedics, No.1 Hospital of China Medical University, Shenyang, China. liliangman2@126.com. OBJECTIVE: The aim of this study is to assess the prevalence of nonunion in patients with tibia fracture and the association between influencing factors and tibia fracture nonunion. METHOD: A database searches of PubMed, the Cochrane Library, EMBASE, China National Knowledge Infrastructure (CNKI), Weipu database, and Wanfang database from inception until June 2019 was conducted. The pooled prevalence, odds ratio (OR), and 95% confidence intervals (CI) were calculated with Stata software. RESULTS: In this study, 111 studies involving 41,429 subjects were included. In the study of the relationship between influencing factors and tibia fracture nonunion, 15 factors significantly influenced the fracture union, including > 60 years old, male, tobacco smoker, body mass index > 40, diabetes, nonsteroidal anti-inflammatory drugs (NSAIDs) user, opioids user, fracture of middle and distal tibia, high-energy fracture, open fracture, Gustilo-Anderson grade IIIB or IIIC, Müller AO Classification of Fractures C, open reduction, fixation model, and infection. CONCLUSION: The prevalence of nonunion in patients with tibia fracture was 0.068 and 15 potential factors were associated with the prevalence. Closed reduction and minimally invasive percutaneous plate osteosynthesis (MIPPO) have the low risks of nonunion for the treatment of tibial fractures. DOI: 10.1186/s13018-020-01904-2 PMCID: PMC7469357