Editorial Commentary: Tension of the Repair During Rotator Cuff Surgery Appears to Matter More Than Medial-Lateral Footprint Coverage.

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Abstract

[Indexed for MEDLINE] Conflict of interest statement: Disclosures The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: M.X. is on the editorial or governing board of Arthroscopy. G.D.A. is a board or committee member of American Academy of Orthopaedic Surgeons, American Orthopaedic Society for Sports Medicine, and International Society of Arthroscopy, Knee Surgery, and Orthopaedic Sports Medicine; is on the editorial or governing board of Arthroscopy; receives other financial or material support from Arthrex and Stryker; is a paid consultant for Cytonics, Fidia Pharma, RubiconMD, and Sideline Sports Doc; owns stock or stock options in Cytonics; is an unpaid consultant for TeachAIDS; receives royalty or license payments from Orthofix Medical: and receives educational support from Evolution Surgical. 9. J Shoulder Elbow Surg. 2012 Feb;21(2):266-77. doi: 10.1016/j.jse.2011.11.016. Biomimetic scaffold design for functional and integrative tendon repair. Zhang X(1), Bogdanowicz D, Erisken C, Lee NM, Lu HH. Author information: (1)Biomaterials and Interface Tissue Engineering Laboratory, Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA. Rotator cuff tears represent the most common shoulder injuries in the United States. The debilitating effect of this degenerative condition coupled with the high incidence of failure associated with existing graft choices underscores the clinical need for alternative grafting solutions. The 2 critical design criteria for the ideal tendon graft would require the graft to not only exhibit physiologically relevant mechanical properties but also be able to facilitate functional graft integration by promoting the regeneration of the native tendon-to-bone interface. Centered on these design goals, this review will highlight current approaches to functional and integrative tendon repair. In particular, the application of biomimetic design principles through the use of nanofiber- and nanocomposite-based scaffolds for tendon tissue engineering will be discussed. This review will begin with nanofiber-based approaches to functional tendon repair, followed by a section highlighting the exciting research on tendon-to-bone interface regeneration, with an emphasis on implementation of strategic biomimicry in nanofiber scaffold design and the concomitant formation of graded multi-tissue systems for integrative soft-tissue repair. This review will conclude with a summary and discussion of future directions. Copyright © 2012 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Mosby, Inc. All rights reserved. DOI: 10.1016/j.jse.2011.11.016 PMCID: PMC3260004