Anterior transposition compared with simple decompression for treatment of cubital tunnel syndrome. A meta-analysis of randomized, controlled trials.

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Abstract

[Indexed for MEDLINE] 18. Eur J Endocrinol. 2008 Oct;159(4):369-73. doi: 10.1530/EJE-08-0327. Epub 2008 Jul 16. The pathology of the ulnar nerve in acromegaly. Tagliafico A(1), Resmini E, Nizzo R, Derchi LE, Minuto F, Giusti M, Martinoli C, Ferone D. Author information: (1)Department of Radiology R, University of Genova, Viale Benedetto XV, 6, I-16132 Genova, Italy. CONTEXT: Acromegalic patients may complain of sensory disturbances in their hands. Cubital tunnel syndrome, the ulnar nerve neuropathy at the cubital tunnel (UCT), in acromegalic patients has never been reported. OBJECTIVE: To describe and assess the prevalence of UCT in acromegalic patients and the effects of 1 year of therapy on UCT. PATIENTS: We examined prospectively 37 acromegalic patients with no history of polyneuropathy, acute trauma at the elbow, no diabetes or hypothyroidism with clinical examination, nerve conduction studies (NCS), and high-resolution ultrasound (US). A control group was made by 50 volunteers. The local ethics committee approved the study and written informed consent was obtained from all subjects involved in the study. INTERVENTION: Clinical history, physical examination, NCS, and US were used to diagnose UCT at the beginning of the study and after 1 year. RESULTS: In 8 of 37 patients, a diagnosis of UCT was made at the beginning of the study reflecting a prevalence of 21%. After 1 year, 5 of 8 (62.5%) patients reported clinical and NCS improvements and evident US reduction of nerve cross-sectional area (CSA; 16.7+/-2.9 mm(2) vs 12.2+/-3.1 mm(2); P