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PubMed Randomized Controlled Trial Evidence High

Robotic Arthroplasty Clinical and cost Effectiveness Randomised controlled trial (RACER-knee): a study protocol.

BMJ open | 2023 | Griffin J, Davis ET, Parsons H, Gemperle Mannion E

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Source
PubMed
Type
Randomized Controlled Trial
Evidence
High

Abstract

[Indexed for MEDLINE] Conflict of interest statement: Competing interests: Stryker is providing funding for consumables, preoperative CT costs and 10 min of theatre time, according to contractual arrangements. They also fund some postoperative CT costs in the learning effects study. Appropriate contracts are in place to ensure the independence of the trial team with regard to study design, data collection, management, analysis and interpretation in line with NIHR reporting standards. Multiple investigators are investigators on two other NIHR-funded studies receiving additional support for treatment costs from Stryker, START:REACTS (16/61/18) (AM, HP, CEH, JM and MU) and RACER-Hip (NIHR131407) (AM, ETD, HP, SR, CEH, DRE, JM, FSH, JAS and MU). The full independence of the investigators of these related studies are protected by legal agreements, similar to this study. FSH receives funding from Stryker to run clinical studies. Multiple authors report other unrelated research grants from NIHR during the conduct of the study. DRE, HP and JG are supported from NIHR Research Capability Funding via University Hospitals Coventry and Warwickshire. MU is chief investigator or coinvestigator on multiple previous and current research grants from the UK National Institute for Health Research, Arthritis Research UK and is a coinvestigator on grants funded by the Australian NHMRC and Norwegian MRC. He was an NIHR Senior Investigator until March 2021. He has received travel expenses for speaking at conferences from the professional organisations hosting the conferences. He is a director and shareholder of Clinvivo that provides electronic data collection for health services research. He is part of an academic partnership with Serco Ltd, funded by the European Social Fund, related to return to work initiatives. Until March 2020 he was an editor of the NIHR journal series, and a member of the NIHR Journal Editors Group, for which he received a fee. 12. Arch Orthop Trauma Surg. 2025 May 15;145(1):295. doi: 10.1007/s00402-025-05911-y. Direct lateral vs. posterior-lateral approach in robotic-assisted total hip arthroplasty: clinical and radiographic comparison. Bertugli E(1), Marcovigi A(2), Grandi G(2), Catani F(2). Author information: (1)Department of Orthopaedic Surgery, Azienda Ospedaliero-Universitaria Policlinico di Modena, University of Modena and Reggio-Emilia, Modena, Italy. enricobertugli@gmail.com. (2)Department of Orthopaedic Surgery, Azienda Ospedaliero-Universitaria Policlinico di Modena, University of Modena and Reggio-Emilia, Modena, Italy. INTRODUCTION: The main goal of this study was to compare patient outcomes following robotic-arm assisted THA (RTHA) using the direct lateral approach (DLA) and the posterior-lateral approach (PLA) by analysing the clinical and radiographical data. MATERIALS AND METHODS: 203 consecutive patients diagnosed with end stage hip osteoarthritis underwent RTHA at the same orthopaedic centre between 2015 and 2019. Patients were divided in two groups based on the surgical approach where 95 patients received PLA and 108 received DLA. All patients were assessed pre-operatively and at minimum 3-year follow-up using Harris Hip Score (HHS) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). A radiographic evaluation was performed for every patient to assess the incidence of heterotopic ossification (HO). RESULTS: Patients in the PLA cohort had higher scores in the post-operative WOMAC when compared to the DLA group (PLA: 96.2 ± 8.2 vs. DLA: 93.6 ± 10.3, p = 0.05). There was no statistical difference in the post-op HHS (PLA 86.3 ± 7 vs. DLA: 86.3 ± 9.5, p = 0.97). Accurate component positioning was achieved according to the pre-operative planning in both groups. There were no cases of dislocation. We found a significantly higher incidence of HO in the DLA group (59.3%) compared to the PLA group (12.6%). However, this difference was not associated with a poorer clinical outcome. CONCLUSIONS: Current controversy still persists regarding the surgical approach without clear evidence about which one is more appropriate. Nowadays, it seems that surgeons' skill and experience to perform an approach are still more relevant than the choice of the approach. Both PLA and DLA represent valid surgical options for performing RTHA, yielding excellent clinical outcomes without clear evidence of superiority of one approach over the other. © 2025. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature. DOI: 10.1007/s00402-025-05911-y

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