Journal of orthopaedic surgery and research | 2023 | Alzakri A, AlMuhid F, Almousa N, Aljehani M
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[Indexed for MEDLINE] Conflict of interest statement: No potential conflict of interest relevant to this article was reported. 15. J Bone Joint Surg Am. 1995 Sep;77(9):1362-9. doi: 10.2106/00004623-199509000-00012. Scoliosis in familial dysautonomia. Operative treatment. Rubery PT(1), Spielman JH, Hester P, Axelrod E, Burke SW, Levine DB. Author information: (1)Hospital for Special Surgery, New York Hospital-Cornell University Medical College, New York City, USA. The results of operative treatment of scoliosis were reviewed for twenty-two patients (ten boys and twelve girls) who had familial dysautonomia, an autosomal recessive disorder affecting primarily Ashkenazi Jews. The indication for operative intervention was progressive kyphoscoliosis to 45 degrees or more in a skeletally immature patient for whom bracing had failed. The mean age at the time of the operation was fifteen years and five months (range, eight years and two months to nineteen years). Seventeen patients had a thoracic curve with a mean preoperative Cobb angle of 69 degrees (range, 47 to 112 degrees), and five patients had a double major curve with a mean preoperative Cobb angle of 71 degrees (range, 42 to 87 degrees) for the cephalad curves and 60 degrees (range, 45 to 72 degrees) for the caudad curves. Twenty patients had a rigid kyphosis; in fourteen, the apex was at the seventh thoracic vertebra or more cephalad. Two patients had a lordoscoliosis. The mean preoperative kyphosis was 64 degrees (range, 12 to 110 degrees) in the thirteen patients who had a thoracic curve and for whom information regarding kyphosis was available, and it was 70 degrees (range, 54 to 84 degrees) in the five patients who had a double major curve. Postoperior spinal arthrodesis and instrumentation was performed in all patients. Two patients had an anterior arthrodesis as well because of the severity and rigidity of the curve. Allograft bone was used in eighteen patients. Postoperatively, all patients were managed with a body cast or with a custom-molded thoracolumbar brace.(ABSTRACT TRUNCATED AT 250 WORDS) DOI: 10.2106/00004623-199509000-00012
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