Current Status and Prospects of Clinical Treatment of Osteosarcoma.

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Abstract

[Indexed for MEDLINE] Conflict of interest statement: Declaration of Conflicting Interests: The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. 9. J Knee Surg. 2019 Apr;32(4):315-321. doi: 10.1055/s-0038-1672123. Epub 2018 Sep 27. Allograft Reconstruction of the Knee-Methods and Outcomes. Temple HT(1)(2). Author information: (1)Office of Translational Research and Economic Development, Nova Southeastern University, Fort Lauderdale, Florida. (2)Department of Surgery, Mercy Hospital, Miami, Florida. Although allograft usage has decreased over the past three decades in favor of segmental metal implants, they still have an important role in the reconstruction of large osteochondral defects following tumor resection. The decline of allografts in limb salvage is multifactorial and includes limited availability, technical difficulty, increased rates of infection and fracture, and unpredictable results. There are circumstances where allograft transplantation is useful around the knee resulting in improved function, bone and joint preservation, and acceptable long-term outcomes. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA. DOI: 10.1055/s-0038-1672123