Glutamine Promotes Rotator Cuff Healing by Ameliorating Age-Related Osteoporosis.

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Abstract

[Indexed for MEDLINE] Conflict of interest statement: Disclosure: No external funding was received for this work. The Disclosure of Potential Conflicts of Interest forms are provided with the online version of the article ( http://links.lww.com/JBJS/I517 ). 10. Med Glas (Zenica). 2021 Feb 1;18(1):186-191. doi: 10.17392/1305-21. Biological augmentation strategies in rotator cuff repair. Özdemir E(1), Karaguven D(2), Turhan E(1), Huri G(1). Author information: (1)Department of Orthopaedics and Traumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey. (2)Department of Orthopaedics and Traumatology, Ufuk University Faculty of Medicine, Ankara, Turkey. Rotator cuff tears (RCT) are a common problem encountered by orthopaedic surgeons. The incidence of re-tears (up to 94%) following surgical repair of RCTs renders the management of RCTs challenging. This higher re-tear rate has been attributed to the failure of healing at the tendon-bone junction. Biological augmentation methods such as growth factors, stem cell therapies, and biomaterials have been developed to promote the healing at the tendon-bone junction. Growth factors and stem cell therapies have been intensively studied in mid to large RCTs. Biomaterials have been generally utilized for large or massive RCTs. However, these newly generated biological augmentation strategies are mostly studied in animal models. The efficacy and safety of the biological augmentation methods in humans need further investigation. In this review, we aimed to highlight the most recent advancements in RCT surgical repair with biological augmentation. Copyright© by the Medical Assotiation of Zenica-Doboj Canton. DOI: 10.17392/1305-21