Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association | 2020 | Ciccone W 2nd
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[Indexed for MEDLINE] 19. Arthroscopy. 2024 Aug;40(8):2184-2185. doi: 10.1016/j.arthro.2024.02.025. Epub 2024 Feb 28. Editorial Commentary: Tranexamic Acid Shown to Not Inhibit Healing Following Rotator Cuff Repair in Rats. Ilahi OA. Comment on Arthroscopy. 2024 Aug;40(8):2174-2183. doi: 10.1016/j.arthro.2024.01.027. As use of tranexamic acid (TXA) to decrease operative bleeding has increased during various orthopaedic surgical procedures, there has been corresponding increased interest regarding additional potential benefits-and also potential risks-of its use. By lessening bleeding during and shortly after arthroscopic surgery, some potential benefits include less postoperative pain, less hemarthrosis, and subsequent decreased formation of scar adhesions, resulting in less permanent stiffness. However, use of this pharmacologic agent also raises the possibility of negative effects upon tissue healing. In a rat rotator cuff repair model, no lasting significant benefit was associated with TXA administration, including no long-term decreased adhesions or stiffness. On the other hand, no adverse effects regarding healing were noted with TXA. Copyright © 2024 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved. DOI: 10.1016/j.arthro.2024.02.025
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