Outcomes of different bearings in total hip arthroplasty - implant survival, revision causes, and patient-reported outcome.

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Abstract

[Indexed for MEDLINE] 19. Clin Orthop Relat Res. 2022 Oct 1;480(10):1912-1925. doi: 10.1097/CORR.0000000000002275. Epub 2022 Jun 16. Do Dual-mobility Cups Reduce Revision Risk in Femoral Neck Fractures Compared With Conventional THA Designs? An International Meta-analysis of Arthroplasty Registries. Farey JE(1), Masters J(2), Cuthbert AR(3), Iversen P(4), van Steenbergen LN(5), Prentice HA(6), Adie S(7), Sayers A(8), Whitehouse MR(8)(9), Paxton EW(6), Costa ML(2), Overgaard S(4)(10)(11), Rogmark C(12)(13), Rolfson O(12)(14), Harris IA(1)(3)(15). Author information: (1)Institute for Musculoskeletal Health, King George V Building, Royal Prince Alfred Hospital, University of Sydney, Sydney, Australia. (2)Oxford Trauma and Emergency Care, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, UK. (3)Australian Orthopaedic Association National Joint Replacement Registry, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia. (4)Danish Hip Arthroplasty Registry, Aarhus, Denmark. (5)Dutch Arthroplasty Register, s'-Hertogenbosch, the Netherlands. (6)Surgical Outcomes and Analysis, Kaiser Permanente, San Diego, CA, USA. (7)St George and Sutherland Clinical School, University of New South Wales, Sydney, Australia. (8)Bristol Medical School, University of Bristol, Bristol, UK. (9)National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust and University of Bristol, Bristol, UK. (10)Copenhagen University Hospital, Bispebjerg, Department of Orthopaedic Surgery and Traumatology, Copenhagen, Denmark. (11)University of Copenhagen, Department of Clinical Medicine, Faculty of Health and Medical Sciences, Copenhagen, Denmark. (12)Swedish Arthroplasty Register, Gothenburg, Sweden. (13)Lund University, Skane University Hospital, Department of Orthopaedics, Malmö, Sweden. (14)Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. (15)Ingham Institute for Applied Medical Research, South Western Sydney Clinical School, University of New South Wales, Sydney, Australia. Comment in Clin Orthop Relat Res. 2022 Oct 1;480(10):1926-1928. doi: 10.1097/CORR.0000000000002353. BACKGROUND: Dual-mobility cups in THA were designed to reduce prosthesis instability and the subsequent risk of revision surgery in high-risk patients, such as those with hip fractures. However, there are limited data from clinical studies reporting a revision benefit of dual-mobility over conventional THA. Collaboration between anthroplasty registries provides an opportunity to describe international practice variation and compare between-country, all-cause revision rates for dual-mobility and conventional THA. QUESTIONS/PURPOSES: We summarized observational data from multiple arthroplasty registries for patients receiving either a dual-mobility or conventional THA to ask: (1) Is dual-mobility use associated with a difference in risk of all-cause revision surgery compared with conventional THA? (2) Are there specific patient characteristics associated with dual-mobility use in the hip fracture population? (3) Has the use of dual-mobility constructs changed over time in patients receiving a THA for hip fracture? METHODS: Six member registries of the International Society of Arthroplasty Registries (from Australia, Denmark, Sweden, the Netherlands, the United Kingdom, and the United States) provided custom aggregate data reports stratified by acetabular cup type (dual-mobility or conventional THA) in primary THA for hip fracture between January 1, 2002, and December 31, 2019; surgical approach; and patient demographic data (sex, mean age, American Society of Anesthesiologists class, and BMI). The cumulative percent revision and mortality were calculated for each registry. To determine a global hazard ratio of all-cause revision for dual-mobility compared with conventional THA designs, we used a pseudoindividual patient data approach to pool Kaplan-Meier prosthesis revision data from each registry and perform a meta-analysis. The pseudoindividual patient data approach is a validated technique for meta-analysis of aggregate time-to-event survival data, such as revision surgery, from multiple sources. Data were available for 15,024 dual-mobility THAs and 97,200 conventional THAs performed for hip fractures during the study period. RESULTS: After pooling of complete Kaplan-Meier survival data from all six registries, the cumulative percent revision for conventional THA was 4.3% (95% confidence interval [CI] 4.2% to 4.5%) and 4.7% (95% CI 4.3% to 5.3%) for dual-mobility THA at 5 years. We did not demonstrate a lower risk of all-cause revision for patients receiving dual-mobility over conventional THA designs for hip fracture in the meta-analysis once between-registry differences were adjusted for (HR 0.96 [95% CI 0.86 to 1.06]). A lower proportion of dual-mobility procedures were revised for dislocation than conventional THAs (0.9% versus 1.4%) but a higher proportion were revised for infection (1.2% versus 0.8%). In most registries, a greater proportion of dual-mobility THA patients were older, had more comorbidities, and underwent a posterior approach compared with conventional THA (p < 0.001). The proportion of dual-mobility THA used to treat hip fractures increased in each registry over time and constituted 21% (2438 of 11,874) of all THA procedures in 2019. CONCLUSION: The proportion of dual-mobility THAs in patients with hip fractures increased over time, but there was large variation in use across countries represented here. Dual-mobility cups were not associated with a reduction in the overall risk of revision surgery in patients with hip fractures. A randomized controlled trial powered to detect the incidence of dislocation and subsequent revision surgery is required to clarify the efficacy of dual-mobility cups to treat hip fractures. LEVEL OF EVIDENCE: Level III, therapeutic study. Copyright © 2022 by the Association of Bone and Joint Surgeons. DOI: 10.1097/CORR.0000000000002275 PMCID: PMC9473769