The influence of minimalist footwear and stride length reduction on lower-extremity running mechanics and cumulative loading.

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Abstract

[Indexed for MEDLINE] 7. Sci Rep. 2025 Sep 1;15(1):32061. doi: 10.1038/s41598-025-17398-z. Three-Dimensional gait biomechanics in patients with mild knee osteoarthritis. Pan J(1), Xie Z(2), Shen H(1), Luan J(2), Zhang X(3), Liao B(4). Author information: (1)Department of Sports Medicine, Guangzhou Sport University, Guangzhou, 510000, China. (2)School of Sports and Health, Guangzhou Sport University, Guangzhou, 510000, China. (3)Department of Sports Medicine, Guangzhou Sport University, Guangzhou, 510000, China. Sportsmedzxh@sina.com. (4)Department of Sports Medicine, Guangzhou Sport University, Guangzhou, 510000, China. Bagenliao@sina.com. Knee osteoarthritis (KOA) is a common degenerative joint disease in older adults that causes pain and functional impairment. Gait biomechanics in early-stage KOA (Kellgren-Lawrence grades I-II) are understudied. This study aimed to examine differences in three-dimensional gait biomechanics and muscle activation in mild KOA to inform early detection and intervention. Twenty-four patients (aged 55-70 years) with unilateral mild KOA and twelve age- and sex-matched healthy older adults were recruited for evaluation. Participants were instructed to walk at a self-selected, comfortable speed along a 6-meter walkway, and at least five valid gait trials were collected for each individual. Three-dimensional gait analysis was conducted using a motion capture system synchronized with force plates to measure spatiotemporal parameters (gait cycle, step width, walking speed), joint kinematics (ROM, peak angular velocity), and joint kinetics (peak joint moments). Muscle activation levels (normalized to %MVIC) and muscle onset times were recorded using a 16-channel wireless surface electromyography system. Between-group differences were assessed using independent-samples t-tests (p