Evidence Search

Musculoskeletal tumours throughout history and beyond: Clinical features, imaging, staging and biopsy.

JPMA. The Journal of the Pakistan Medical Association | 2020 | Zubairi AJ, Ali Hasan OH, Mustafa M, Umer M

[Indexed for MEDLINE] 17. J Knee Surg. 2022 May;35(6):619-624. doi: 10.1055/s-0042-1743225. Epub 2022 Feb 18. Management of Pathologic Fractures around the Knee: Part 2-Proximal Tibia. Martin JR(1), Auran RL(1), Duran MD(2), de Comas AM(1)(2), Jacofsky DJ(2). Author information: (1)Department of Orthopaedic Surgery, University of Arizona College of Medicine, Phoenix, Arizona. (...

Pathological fractures in primary bone sarcomas: A review article

Journal of Orthopaedic Reports | 2025 | Philani Ntombela, Wofhatwa Ndou

Predictors for pathological bone fractures in children undergoing liver transplantation: A retrospective cohort study.

Pediatric transplantation | 2024 | Astolfi D, Rock N, Ceroni D, Wildhaber BE

[Indexed for MEDLINE] 11. Unfallchirurg. 2021 Sep;124(9):731-737. doi: 10.1007/s00113-021-01051-1. Epub 2021 Jul 13. [Oncologic aspects in treatment of pathologic fractures]. [Article in German; Abstract available in German from the publisher] Eggers H(1)(2), Wichmann J(2)(3), Omar M(4), Länger F(2)(5), Ivanyi P(6)(7)(8). Author information: (1)Klinik für Hämatologie, Hämostase...

Pathological Fractures in Benign Bone Lesions - Diagnosis and Therapy.

Zeitschrift fur Orthopadie und Unfallchirurgie | 2024 | Spodeck D, Guder W, Streitbürger A, Dudda M

[Indexed for MEDLINE] Conflict of interest statement: J. Hardes und A. Streitbürger weisen auf folgende Beziehung hin: Forschungsunterstützung durch die Firma Implantcast, Buxtehude. D. Spodeck, W.Guder,M.Nottrott, L.Podleska,und M.Dudda geben an, dass kein Interessenkonflikt besteht.

Osteoporosis in children and adolescents: when to suspect and how to diagnose it.

European journal of pediatrics | 2022 | Ciancia S, van Rijn RR, Högler W, Appelman-Dijkstra NM

[Indexed for MEDLINE] Conflict of interest statement: The authors have no conflict of interests to declare. 9. Crit Rev Oncol Hematol. 2016 May;101:169-83. doi: 10.1016/j.critrevonc.2016.03.006. Epub 2016 Mar 5. Myeloma bone and extra-medullary disease: Role of PET/CT and other whole-body imaging techniques. Rubini G(1), Niccoli-Asabella A(2), Ferrari C(1), Racanelli V(3), Magg...

Management of Pathologic Fractures around the Knee: Part 2-Proximal Tibia.

The journal of knee surgery | 2022 | Martin JR, Auran RL, Duran MD, de Comas AM

[Indexed for MEDLINE] Conflict of interest statement: None declared. 18. J Am Acad Orthop Surg Glob Res Rev. 2022 Jan 11;6(1):e21.00137. doi: 10.5435/JAAOSGlobal-D-21-00137. Systemic Mastocytosis Presenting as Pathologic Intertrochanteric Femur Fracture. Shah A(1), Bhan R, Pey EP, Riordan H, Khan F. Author information: (1)From the Stony Brook University Hospital, Department of...

[Oncologic aspects in treatment of pathologic fractures].

Der Unfallchirurg | 2021 | Eggers H, Wichmann J, Omar M, Länger F

[Indexed for MEDLINE] 12. Nephrol Dial Transplant. 2024 Dec 20;40(1):48-59. doi: 10.1093/ndt/gfae197. Multidisciplinary team approach for CKD-associated osteoporosis. Hansen D(1)(2), Jørgensen HS(3)(4), Andersen TL(5)(6)(7)(8), Ferreira AC(9)(10), Ferreira A(9)(10), de Jongh R(11)(12), Keronen S(13), Kröger H(14)(15), Lafage-Proust MH(16), Martola L(13), Poole KES(17), Tong X(1...

[Radiological aspects in the diagnostics of pathological fractures].

Der Unfallchirurg | 2021 | von Falck C, Omar M

[Indexed for MEDLINE] 15. Curr Opin Pediatr. 2012 Feb;24(1):46-9. doi: 10.1097/MOP.0b013e32834ec8eb. Vitamin D deficiency: a paediatric orthopaedic perspective. Clarke NM(1), Page JE. Author information: (1)University Hospital Southampton, NHS Foundation Trust Southampton University Hospitals, Southampton General Hospital, Southampton, Hampshire, UK. ortho@soton.ac.uk PURPOSE O...

[Radiologic diagnosis of pathologic fractures].

Der Radiologe | 2020 | Wuennemann F, Kintzelé L, Weber MA, Kauczor HU

[Indexed for MEDLINE] 3. J Med Case Rep. 2023 Dec 17;17(1):517. doi: 10.1186/s13256-023-04249-6. Sclerosing epithelioid fibrosarcoma associated with WRN gene variant presenting as chronic dyspnea and pathologic cervical fracture: a case report and review of the literature. Phan AT(1)(2), Ghantarchyan H(3)(4), Khosravi C(5)(4), Maknouni B(5)(4), Bhagat A(3)(4), Chen J(4), Ibrahi...

Myeloma bone and extra-medullary disease: Role of PET/CT and other whole-body imaging techniques.

Critical reviews in oncology/hematology | 2016 | Rubini G, Niccoli-Asabella A, Ferrari C, Racanelli V

[Indexed for MEDLINE] 10. Pediatr Transplant. 2024 May;28(3):e14755. doi: 10.1111/petr.14755. Predictors for pathological bone fractures in children undergoing liver transplantation: A retrospective cohort study. Astolfi D(1), Rock N(1)(2), Ceroni D(3), Wildhaber BE(1)(4). Author information: (1)Department of Pediatrics, Gynecology, and Obstetrics, Swiss Pediatric Liver Center,...

Bone metastases of unknown origin: epidemiology and principles of management.

Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology | 2015 | Piccioli A, Maccauro G, Spinelli MS, Biagini R

[Indexed for MEDLINE] 7. Instr Course Lect. 2021;70:453-464. Pediatric Tumor Management: Current and Controversial. Thacker MM, Binitie OT, Lindberg AW, Arkader A. Bone and soft-tissue tumors are common in the pediatric population. It is important to be familiar with the appropriate workup, principles of biopsy, differences between unicameral and aneurysmal bone cysts, and prin...

Multidisciplinary team approach for CKD-associated osteoporosis.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association | 2024 | Hansen D, Jørgensen HS, Andersen TL, Ferreira AC

[Indexed for MEDLINE] Conflict of interest statement: D.H. reports research grant from Vifor Pharma and Gedeon Richter and consultancy fees and lecture fees from UCB Nordic, GSK and AstraZeneca. A.C.F. reports lecture fees from Vifor and AstraZeneca. R.J. received fees as site PI in a pharmacy-initiated study (SHP634-401) of Takeda. S.K. reports consultancy fees from Vifor Phar...

Sclerosing epithelioid fibrosarcoma associated with WRN gene variant presenting as chronic dyspnea and pathologic cervical fracture: a case report and review of the literature.

Journal of medical case reports | 2023 | Phan AT, Ghantarchyan H, Khosravi C, Maknouni B

[Indexed for MEDLINE] Conflict of interest statement: The authors declare that they have no competing interests. 4. JBJS Rev. 2023 Jan 10;11(1). doi: 10.2106/JBJS.RVW.22.00166. eCollection 2023 Jan 1. Team Approach: Management of Pathologic Fractures. Hammad A(1), Ahmed O, Connell PP, Olson D, Balach T. Author information: (1)Department of Orthopaedic Surgery and Rehabilitation...

Vitamin D deficiency: a paediatric orthopaedic perspective.

Current opinion in pediatrics | 2012 | Clarke NM, Page JE

[Indexed for MEDLINE] 16. J Pak Med Assoc. 2020 Sep;70(9):1605-1610. doi: 10.5455/JPMA.11954. Musculoskeletal tumours throughout history and beyond: Clinical features, imaging, staging and biopsy. Zubairi AJ(1), Ali Hasan OH(2), Mustafa M(2), Umer M(3). Author information: (1)Department of Spine Surgery, Combined Military Hospital, Rawalpindi, Pakistan. (2)The Aga Khan Universi...

Systemic Mastocytosis Presenting as Pathologic Intertrochanteric Femur Fracture.

Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews | 2022 | Shah A, Bhan R, Pey EP, Riordan H

[Indexed for MEDLINE] 19. Eur Radiol. 2007 Oct;17(10):2656-62. doi: 10.1007/s00330-007-0582-5. Epub 2007 Feb 17. Vertebroplasty in the treatment of osteoporotic vertebral body fracture. Hoffmann RT(1), Jakobs TF, Trumm C, Weber C, Glaser C, Reiser MF. Author information: (1)Institute of Clinical Radiology, University of Munich-Grosshadern, Marchioninistrasse 15, 81377, Munich,...

Undiagnosed Chronic Kidney Disease in a Child With Fractures Presenting to a Pediatric Orthopedic Clinic

Orthopaedic Nursing | 2026

Pathological Fractures Around the Hip: Approach to Diagnosis and Management

Nepal Orthopedic Association Journal | 2025 | Rishi Ram Poudel

Pathological fractures due to metastatic disease are common around the hip (proximal femur and acetabulum) and represent an escalating concern in musculoskeletal oncology. These fractures should not be fixed straight away and management should focus on comprehensive clinical, laboratory, imaging workup and biopsy, and treatment plan should be tailored and personalized after inp...

Treatment of Bilateral Distal Femoral Shaft Fractures in a Paraplegic Patient with Intramedullary Nailing: A Case Report

Journal of Orthopaedic Case Reports | 2025 | Ernesto S Quinto Jr., Brendan J Liakos, William L Pistel

Introduction: Lower extremity fractures are a frequent complication in patients with chronic spinal cord injury due to significant bone mineral density loss and altered bone metabolism. While non-operative management has traditionally been favored, advances in surgical techniques have expanded treatment options, including intramedullary nailing and plate fixation. However, the...

Practical strategies to lower radiation exposure in pediatrics distal radius fractures: An orthopedic view

Journal of Orthopaedic Reports | 2024 | Alireza Mobasseri

Orthopaedic Trauma Society: Subtrochanteric Fractures

OrthoMedia | 2024

Team Approach: Management of Pathologic Fractures.

JBJS reviews | 2023 | Hammad A, Ahmed O, Connell PP, Olson D

[Indexed for MEDLINE] Conflict of interest statement: Disclosure: The Disclosure of Potential Conflicts of Interest forms are provided with the online version of the article (http://links.lww.com/JBJSREV/A892). 5. Arch Orthop Trauma Surg. 2015 Jan;135(1):59-67. doi: 10.1007/s00402-014-2113-6. Epub 2014 Nov 16. Urinary incontinence and poor functional status in fragility fractur...

Orthopedic Implant Fixation Strategies for Multiple Fractures in a Single Bone

Handbook of Orthopaedic Trauma Implantology | 2023 | Kai Hoffeld, Peter Biberthaler, Saseendar Shanmugasundaram

Vertebroplasty in the treatment of osteoporotic vertebral body fracture.

European radiology | 2007 | Hoffmann RT, Jakobs TF, Trumm C, Weber C

[Indexed for MEDLINE] 20. Z Orthop Unfall. 2024 Feb;162(1):69-78. doi: 10.1055/a-1850-2540. Epub 2022 Jul 26. Pathological Fractures in Benign Bone Lesions - Diagnosis and Therapy. [Article in English, German; Abstract available in German from the publisher] Spodeck D(1), Guder W(2), Streitbürger A(2), Dudda M(3)(1), Podleska LE(2), Nottrott M(2), Hardes J(2). Author informatio...

Pediatric Tumor Management: Current and Controversial.

Instructional course lectures | 2021 | Thacker MM, Binitie OT, Lindberg AW, Arkader A

[Indexed for MEDLINE] 8. Eur J Pediatr. 2022 Jul;181(7):2549-2561. doi: 10.1007/s00431-022-04455-2. Epub 2022 Apr 6. Osteoporosis in children and adolescents: when to suspect and how to diagnose it. Ciancia S(1), van Rijn RR(2), Högler W(3), Appelman-Dijkstra NM(4), Boot AM(5), Sas TCJ(6)(7), Renes JS(6). Author information: (1)Department of Pediatrics, Subdivision of Endocrino...

Outcome of percutaneous locked plating of extra-articular distal tibial metaphyseal fractures

Hong Kong Journal of Orthopaedic Research | 2021 | Yasser Youssef Abed, Mohamed Arafa

Introduction: Management of fractures involving the distal tibial metaphysis is one of the most challenging and controversial issue due to poor soft tissue envelop. Multiple different fixation modalities are available with different outcome. Percutaneous plating of the distal tibia fracture is gaining more popularity due to minimal interruption of the fracture biology and favor...

Chapter 71: Pathological (neoplastic) Fractures

Decision Making in Orthopaedic Trauma | 2017

Treatment of pathological fractures of the long bones.

EFORT open reviews | 2016 | Willeumier JJ, van der Linden YM, van de Sande MAJ, Dijkstra PDS

Conflict of interest statement: Conflict of Interest: None declared. 14. Unfallchirurg. 2021 Sep;124(9):695-703. doi: 10.1007/s00113-021-01067-7. Epub 2021 Jul 29. [Radiological aspects in the diagnostics of pathological fractures]. [Article in German; Abstract available in German from the publisher] von Falck C(1), Omar M(2). Author information: (1)Institut für Diagnostische u...

Endoprosthetic treatment of primary bone sarcomas with pathological fractures

SA Orthopaedic Journal | 2016 | Thomas; L Hilton, Keith Hosking

Urinary incontinence and poor functional status in fragility fracture patients: an underrecognized and underappreciated association.

Archives of orthopaedic and trauma surgery | 2015 | Gosch M, Talasz H, Nicholas JA, Kammerlander C

[Indexed for MEDLINE] 6. J Orthop Traumatol. 2015 Jun;16(2):81-6. doi: 10.1007/s10195-015-0344-0. Epub 2015 Mar 1. Bone metastases of unknown origin: epidemiology and principles of management. Piccioli A(1), Maccauro G, Spinelli MS, Biagini R, Rossi B. Author information: (1)Oncologic Center, "Palazzo Baleani", Teaching Hospital Policlinico Umberto I, Rome, Italy. Metastases ar...

Pathological fractures

Orthopaedic Trauma | 2014 | James Wong, Harry Krishnan, Tim Briggs, Will Aston

Osteoporosis. Definition and clinical presentation.

Spine | 1997 | Glaser DL, Kaplan FS

[Indexed for MEDLINE] 2. Radiologe. 2020 Jun;60(6):498-505. doi: 10.1007/s00117-020-00693-3. [Radiologic diagnosis of pathologic fractures]. [Article in German] Wuennemann F(1), Kintzelé L(2), Weber MA(3), Kauczor HU(2), Rehnitz C(2). Author information: (1)Diagnostische und Interventionelle Radiologie, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg...

Pathological fractures

Oxford Medicine Online | 2011 | D.E. Porter

♦ Pathological fractures should be recognized before treatment, but often are not.♦ If solitary and potentially malignant, pathological fractures should be investigated prior to treatment.♦ Inappropriate management may compromise outcome.♦ Maximize patient fitness for surgery.♦ Preoperative assessment to look for other tumours e.g. CT scan of chest and abdomen.♦ Biopsy if possi...

Non-Transfusion orthopaedic Surgery in complicated fractures among Jehovah’s witnesses in Calabar, Nigeria: Case report

The Internet Journal of Orthopedic Surgery | 2009

Pathological Fractures

Key Topics in Orthopaedic Trauma Surgery | 1999

Pathological Fractures

Selected References in Orthopaedic Trauma | 1989 | A. H. C. Ratliff, J. H. Dixon, P. A. Magnussen, S. K. Young