Evidence Search

Bone Defects in Revision Total Knee Arthroplasty and Management.

Orthopaedic surgery | 2019 | Lei PF, Hu RY, Hu YH

[Indexed for MEDLINE] 19. J Shoulder Elbow Surg. 2014 Jul;23(7):e149-57. doi: 10.1016/j.jse.2013.09.023. Epub 2013 Dec 14. Nonstandard glenoid components for bone deficiencies in shoulder arthroplasty. Cil A(1), Sperling JW(2), Cofield RH(3). Author information: (1)Department of Orthopaedics, University of Missouri, Kansas City, MO, USA. (2)Department of Orthopedic Surgery, May...

HDAC6/Trim21 aggravates macrophage inflammatory response and titanium-induced osteolysis via GSDMD signaling pathway.

Journal of immunology (Baltimore, Md. : 1950) | 2025 | Chen J, Liu T, Luo J, Chen Z

[Indexed for MEDLINE] 9. J Ethnopharmacol. 2024 Jan 10;318(Pt B):117019. doi: 10.1016/j.jep.2023.117019. Epub 2023 Aug 11. Kaempferol attenuates wear particle-induced inflammatory osteolysis via JNK and p38-MAPK signaling pathways. Yu X(1), Wu Q(2), Ren Z(3), Chen B(1), Wang D(1), Yuan T(1), Ding H(1), Wang Y(1), Yuan G(1), Wang Y(1), Zhang L(4), Zhao J(5), Sun Z(6). Author inf...

Osteoblastic ferroptosis inhibition by small-molecule promoting GPX4 activation for peri-prosthetic osteolysis therapy.

Journal of nanobiotechnology | 2024 | Liu X, Wang W, Zhu F, Xu H

[Indexed for MEDLINE] Conflict of interest statement: Declarations. Ethics approval and consent to participate: Clinical samples were collected with permission of the Ethics Committee of the First Affiliated Hospital of Soochow University. All animal experiments were approved by the Ethics Committee of Soochow University. Consent for publication: All authors agree to be publish...

Osthole ameliorates wear particle-induced osteogenic impairment by mitigating endoplasmic reticulum stress via PERK signaling cascade.

Molecular medicine (Cambridge, Mass.) | 2024 | Yu X, Jiang J, Li C, Wang Y

[Indexed for MEDLINE] Conflict of interest statement: Declarations. Ethics approval and consent to participate: All experimental protocols were approved by the Ethical Committee of Nanjing Jinling Hospital, the Affiliated Hospital of Nanjing University Medical School. Consent for publication: Not applicable. Competing interests: The authors declare no competing interests. 3. Mi...

Kaempferol attenuates wear particle-induced inflammatory osteolysis via JNK and p38-MAPK signaling pathways.

Journal of ethnopharmacology | 2024 | Yu X, Wu Q, Ren Z, Chen B

[Indexed for MEDLINE] Conflict of interest statement: Declaration of competing interest The authors declare that they have no conflicts of interest. 10. Planta Med. 2018 Jul;84(11):759-767. doi: 10.1055/s-0043-124594. Epub 2018 Jan 4. Amentoflavone Inhibits Osteoclastogenesis and Wear Debris-Induced Osteolysis via Suppressing NF-κB and MAPKs Signaling Pathways. Zhang Z(1)(2), Z...

Polyethylene Wear and Osteolysis

Advances in Total Hip Arthroplasty | 2024 | Yuya Takakubo, Michiaki Takagi

Quercetin alleviates nanoparticle-induced osteolysis via deactivating pyroptosis.

Biomaterials science | 2023 | Cheng Y, Zhao Z, Zhang S, Wu Y

[Indexed for MEDLINE] 16. J Hand Surg Am. 2014 Dec;39(12):2396-404. doi: 10.1016/j.jhsa.2014.07.046. Epub 2014 Sep 13. Wear particles and osteolysis in patients with total wrist arthroplasty. Boeckstyns ME(1), Toxvaerd A(2), Bansal M(2), Vadstrup LS(2). Author information: (1)Clinic of Hand Surgery, Gentofte Hospital, University of Copenhagen, Denmark, NY; Department of Patholo...

Propionate and butyrate attenuate macrophage pyroptosis and osteoclastogenesis induced by CoCrMo alloy particles.

Military Medical Research | 2022 | Wu YL, Zhang CH, Teng Y, Pan Y

[Indexed for MEDLINE] Conflict of interest statement: The authors declare that they have no competing interests. 4. Foot Ankle Int. 2021 Jan;42(1):55-61. doi: 10.1177/1071100720955155. Epub 2020 Sep 16. Bone Cysts and Osteolysis in Ankle Replacement. Najefi AA(1)(2), Ghani Y(3), Goldberg AJ(1)(4). Author information: (1)UCL Institute of Orthopaedics & Musculoskeletal Research,...

The ketone body β-hydroxybutyrate alleviates CoCrMo alloy particles induced osteolysis by regulating NLRP3 inflammasome and osteoclast differentiation.

Journal of nanobiotechnology | 2022 | Wu Y, Teng Y, Zhang C, Pan Y

[Indexed for MEDLINE] Conflict of interest statement: The authors declare that they have no competing interests. 8. J Immunol. 2025 Sep 1;214(9):2357-2370. doi: 10.1093/jimmun/vkaf112. HDAC6/Trim21 aggravates macrophage inflammatory response and titanium-induced osteolysis via GSDMD signaling pathway. Chen J(1), Liu T(1), Luo J(1), Chen Z(1), Yu Y(1), Sun H(1), Tan M(1), Sun Y(...

Bone Cysts and Osteolysis in Ankle Replacement.

Foot & ankle international | 2021 | Najefi AA, Ghani Y, Goldberg AJ

[Indexed for MEDLINE] 5. Instr Course Lect. 2013;62:207-14. Monitoring and risk of progression of osteolysis after total hip arthroplasty. Ries MD(1), Link TM. Author information: (1)Department of Orthopaedic Surgery, University of California, San Francisco, CA, USA. Osteolysis after total hip arthroplasty (THA) develops in response to particulate wear debris and may not be ass...

Amentoflavone Inhibits Osteoclastogenesis and Wear Debris-Induced Osteolysis via Suppressing NF-κB and MAPKs Signaling Pathways.

Planta medica | 2018 | Zhang Z, Zhao S, Li X, Zhuo X

[Indexed for MEDLINE] Conflict of interest statement: There are no interest conflicts the authors need to declare. 11. Foot Ankle Int. 2017 Apr;38(4):351-359. doi: 10.1177/1071100716682333. Epub 2016 Dec 1. Histological Analysis of Early Osteolysis in Total Ankle Arthroplasty. Schipper ON(1), Haddad SL(2), Pytel P(3), Zhou Y(4). Author information: (1)1 OrthoCarolina Foot and A...

Osteolysis as it Pertains to Total Hip Arthroplasty

Orthopedic Clinics of North America | 2018 | Brian Kurcz, Joseph Lyons, Zain Sayeed, Afshin A. Anoushiravani

Osteoclasts in Periprosthetic Osteolysis: The Charnley Arthroplasty Revisited.

The Journal of arthroplasty | 2017 | Mukka SS, Andersson GN, Hultenby KR, Sköldenberg OG

[Indexed for MEDLINE] 7. J Nanobiotechnology. 2022 Mar 9;20(1):120. doi: 10.1186/s12951-022-01320-0. The ketone body β-hydroxybutyrate alleviates CoCrMo alloy particles induced osteolysis by regulating NLRP3 inflammasome and osteoclast differentiation. Wu Y(#)(1)(2), Teng Y(#)(1), Zhang C(1), Pan Y(3), Zhang Q(1), Zhu X(1), Liu N(1), Su X(1), Lin J(4). Author information: (1)De...

Histological Analysis of Early Osteolysis in Total Ankle Arthroplasty.

Foot & ankle international | 2017 | Schipper ON, Haddad SL, Pytel P, Zhou Y

[Indexed for MEDLINE] 12. Comput Intell Neurosci. 2021 Oct 4;2021:4196241. doi: 10.1155/2021/4196241. eCollection 2021. Osteolysis: A Literature Review of Basic Science and Potential Computer-Based Image Processing Detection Methods. Saadi SB(1), Ranjbarzadeh R(2), Ozeir Kazemi(3), Amirabadi A(1), Ghoushchi SJ(4), Kazemi O(5), Azadikhah S(6), Bendechache M(7). Author informatio...

Outcome of 4 Surgical Treatments for Wear and Osteolysis of Cementless Acetabular Components.

The Journal of arthroplasty | 2017 | Narkbunnam R, Amanatullah DF, Electricwala AJ, Huddleston JI 3rd

[Indexed for MEDLINE] 15. Biomater Sci. 2023 Jun 27;11(13):4616-4629. doi: 10.1039/d3bm00060e. Quercetin alleviates nanoparticle-induced osteolysis via deactivating pyroptosis. Cheng Y(1), Zhao Z(1), Zhang S(2), Wu Y(3), Han Z(4), Li L(5), Teng Y(1), Lin J(4), Liu N(1), He S(6), Yang H(1). Author information: (1)Department of Orthopaedics, The First Affiliated Hospital of Sooch...

MicroRNA-130b Promotes Wear Particle-Induced Osteolysis via Downregulating Frizzled-Related Protein (FRZB).

Current neurovascular research | 2017 | Zheng DZ, Bu YM, Wang L, Liu J

[Indexed for MEDLINE] 18. Orthop Surg. 2019 Feb;11(1):15-24. doi: 10.1111/os.12425. Epub 2019 Feb 27. Bone Defects in Revision Total Knee Arthroplasty and Management. Lei PF(1), Hu RY(2), Hu YH(1). Author information: (1)Department of Orthopaedic Surgery, Xiangya Hospital of Central South University, Changsha, China. (2)Department of Orthopaedic Surgery, Guizhou Provincial Peop...

Wear and Osteolysis of Polyethylene Bearings

Complications after Primary Total Hip Arthroplasty | 2017 | James A. Keeney

Hip Resurfacing Using Highly Cross-linked Polyethylene: Prospective Study Results at 8.5 Years.

The Journal of arthroplasty | 2016 | Pritchett JW

[Indexed for MEDLINE] 14. J Arthroplasty. 2017 Sep;32(9):2799-2805. doi: 10.1016/j.arth.2017.04.028. Epub 2017 Apr 27. Outcome of 4 Surgical Treatments for Wear and Osteolysis of Cementless Acetabular Components. Narkbunnam R(1), Amanatullah DF(2), Electricwala AJ(3), Huddleston JI 3rd(2), Maloney WJ(2), Goodman SB(2). Author information: (1)Siriraj Hospital, Mahidol University...

Review Article: Polyethylene Wear and Osteolysis in Total Hip Arthroplasty

Journal of Orthopaedic Surgery | 2001 | YH Zhu, KY Chiu, WM Tang

Polyethylene wear has been accepted as a major cause of osteolysis in total hip arthroplasty. Submicron particles, which are secondary to abrasive wear, migrate into the effective joint space and stimulate a foreign-body response resulting in bone loss which is mainly mediated by macrophages. Diagnosis depends on serial radiographic evaluation and frequent follow-up. Polyethyle...

Wear particles and osteolysis in patients with total wrist arthroplasty.

The Journal of hand surgery | 2014 | Boeckstyns ME, Toxvaerd A, Bansal M, Vadstrup LS

[Indexed for MEDLINE] 17. Curr Neurovasc Res. 2017;14(1):32-38. doi: 10.2174/1567202614666161123112409. MicroRNA-130b Promotes Wear Particle-Induced Osteolysis via Downregulating Frizzled-Related Protein (FRZB). Zheng DZ(1), Bu YM, Wang L, Liu J. Author information: (1)Department of Joint Surgery, Tianjin Hospital, 406 Jiefang South Road, Hexi District, Tianjin 300211, P.R. Chi...

Nonstandard glenoid components for bone deficiencies in shoulder arthroplasty.

Journal of shoulder and elbow surgery | 2014 | Cil A, Sperling JW, Cofield RH

[Indexed for MEDLINE] 20. J Am Acad Orthop Surg. 2008 May;16(5):243-8. doi: 10.5435/00124635-200805000-00002. Isolated acetabular liner exchange. Lombardi AV Jr(1), Berend KR. Author information: (1)The Ohio State University, Columbus, OH, USA. Comment in J Am Acad Orthop Surg. 2008 Sep;16(9):495-6; author reply 496. During the past two decades, most total hip arthroplasties we...

Monitoring and risk of progression of osteolysis after total hip arthroplasty.

Instructional course lectures | 2013 | Ries MD, Link TM

[Indexed for MEDLINE] 6. J Arthroplasty. 2017 Oct;32(10):3219-3227. doi: 10.1016/j.arth.2017.05.030. Epub 2017 May 22. Osteoclasts in Periprosthetic Osteolysis: The Charnley Arthroplasty Revisited. Mukka SS(1), Andersson GN(2), Hultenby KR(2), Sköldenberg OG(3), Nordahl JP(4), Eisler TM(3). Author information: (1)Department of Surgical and Perioperative Sciences, Umeå Universit...

Orthopedic wear debris mediated inflammatory osteolysis is mediated in part by NALP3 inflammasome activation

Journal of Orthopaedic Research | 2013 | Lyndsey Burton, Daniel Paget, Nikolaus B. Binder, Krista Bohnert

AbstractActivation of myeloid cells by orthopedic particulate debris is a key event in the pathogenesis of periprosthetic osteolysis and implant loosening after total joint replacement (TJR). Several lines of evidence implicate NACHT, LRR, and PYD domains‐containing protein 3 (NALP3) inflammasome‐mediated production of interleukin 1 beta (IL‐1β) in the pathogenesis of clinical...

Thigh mass associated with polyethylene wear-induced osteolysis after cementless total hip arthroplasty

Archives of Orthopaedic and Trauma Surgery | 2010 | Youn-Soo Park, Seung-Jae Lim, Jin-Hong Kim, Ajay Wala

Isolated acetabular liner exchange.

The Journal of the American Academy of Orthopaedic Surgeons | 2008 | Lombardi AV Jr, Berend KR

[Indexed for MEDLINE]

Wear particles and osteolysis

Orthopaedic Bone Cements | 2008 | N. PATIL, S.B. GOODMAN

What patient and surgical factors contribute to implant wear and osteolysis in total joint arthroplasty?

Journal of the American Academy of Orthopaedic Surgeons | 2008 | Audrey K. Tsao, Lynne C. Jones, David G. Lewallen

How prevalent are implant wear and osteolysis, and how has the scope of osteolysis changed since 2000?

Journal of the American Academy of Orthopaedic Surgeons | 2008 | Amanda Marshall, Michael D. Ries, Wayne Paprosky

Wear and Osteolysis Around Total Knee Arthroplasty

Journal of the American Academy of Orthopaedic Surgeons | 2007 | Douglas D.R. Naudie, Deborah J. Ammeen, Gerard A. Engh, Cecil H. Rorabeck

Wear particulate and osteolysis

Orthopedic Clinics of North America | 2005 | Stuart Goodman

Wear and Osteolysis in Total Hip Arthroplasty

Seminars in Arthroplasty | 2005 | Kevin J. Bozic, Michael D. Ries

Particle bioreactivity and wear-mediated osteolysis

The Journal of Arthroplasty | 2004 | Mark L. Wang, Peter F. Sharkey, Rocky S. Tuan

Characteristics of Wear Particles and Osteolysis

Joint Arthroplasty | 1999 | Hirotsugu Ohashi, Yoshinori Kadoya, Akio Kobayashi, Hiroyoshi Iwaki

Effect of polyethylene wear on osteolysis in cementless primary total hip arthroplasty

The Journal of Arthroplasty | 1999 | Chang-Dong Han, Wahn-Sub Choe, Ju-Hyung Yoo