Evidence Search

The Diagnosis and Treatment of Acetabular Bone Loss in Revision Hip Arthroplasty: An International Consensus Symposium.

HSS journal : the musculoskeletal journal of Hospital for Special Surgery | 2022 | Sculco PK, Wright T, Malahias MA, Gu A

Conflict of interest statement: Declaration of Conflicting Interests: The author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: Peter K. Sculco, MD, reports relationships with EOS Imaging, DePuy Synthes, Intellijoint Surgical, and Parvizi Surgical Innovation. Timothy Wright, PhD, reports re...

Combined direct anterior approach and navigation-assisted percutaneous anterograde posterior column fixation for acetabular periprosthetic fractures.

Operative Orthopadie und Traumatologie | 2026 | Beckers G, Simon D, Lerchenberger M, Böcker W

[Indexed for MEDLINE] Conflict of interest statement: Declarations. Conflict of interest: G. Beckers, D. Simon, M. Lerchenberger, W. Böcker, J. Arnholdt, and B.M. Holzapfel declare that they have no competing interests. For this article no studies with human participants or animals were performed by any of the authors. All studies mentioned were in accordance with the ethical s...

Catastrophic Periprosthetic Osteolysis in Total Hip Arthroplasty at 20 Years: A Case Report and Literature Review

Orthopaedic Surgery | 2022 | Dan Xing, Rujun Li, Jiao Jiao Li, Ke Tao

BackgroundPeriprosthetic osteolysis is a serious complication following total hip arthroplasty (THA). However, most orthopedic surgeons only focus on bone loss and hip reconstruction. Thus, it was required to understand the treatment algorithm for periprosthetic osteolysis integrally.Case PresentationA 52‐year‐old Asian male presented with chronic hip pain. A mass appeared on t...

Diagnosis and management of implant debris-associated inflammation.

Expert review of medical devices | 2020 | Goodman SB, Gallo J, Gibon E, Takagi M

[Indexed for MEDLINE] Conflict of interest statement: Declaration of interest The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert...

Bone Defects in Revision Total Knee Arthroplasty and Management.

Orthopaedic surgery | 2019 | Lei PF, Hu RY, Hu YH

[Indexed for MEDLINE] 2. Expert Rev Med Devices. 2020 Jan;17(1):41-56. doi: 10.1080/17434440.2020.1702024. Epub 2019 Dec 17. Diagnosis and management of implant debris-associated inflammation. Goodman SB(1)(2), Gallo J(3), Gibon E(4), Takagi M(5). Author information: (1)Department of Orthopaedic Surgery, Stanford University, Redwood City, CA, USA. (2)Department of Bioengineerin...

What are the guidelines for the surgical and nonsurgical treatment of periprosthetic osteolysis?

The Journal of the American Academy of Orthopaedic Surgeons | 2008 | Stulberg BN, Della Valle AG, Implant Wear Symposium 2007 Clinical Work Group

[Indexed for MEDLINE] 10. J Bone Joint Surg Am. 2004 Sep;86(9):1947-54. doi: 10.2106/00004623-200409000-00013. Magnetic resonance imaging after total hip arthroplasty: evaluation of periprosthetic soft tissue. Potter HG(1), Nestor BJ, Sofka CM, Ho ST, Peters LE, Salvati EA. Author information: (1)Division of Magnetic Resonance Imaging, Hospital for Special Surgery, 535 East 70t...

Functional and radiological outcome of periprosthetic femoral fractures after hip arthroplasty.

Injury | 2015 | Moreta J, Aguirre U, de Ugarte OS, Jáuregui I

[Indexed for MEDLINE] 4. HSS J. 2022 Feb;18(1):8-41. doi: 10.1177/15563316211034850. Epub 2021 Sep 28. The Diagnosis and Treatment of Acetabular Bone Loss in Revision Hip Arthroplasty: An International Consensus Symposium. Sculco PK(1), Wright T(1), Malahias MA(1), Gu A(2), Bostrom M(1), Haddad F(3), Jerabek S(1), Bolognesi M(4), Fehring T(5), Gonzalez DellaValle A(1), Jiranek...

MR Imaging of Knee Arthroplasty Implants.

Radiographics : a review publication of the Radiological Society of North America, Inc | 2015 | Fritz J, Lurie B, Potter HG

[Indexed for MEDLINE] 15. Inflammopharmacology. 2013 Dec;21(6):389-96. doi: 10.1007/s10787-013-0192-6. Epub 2013 Oct 15. Periprosthetic osteolysis after total hip replacement: molecular pathology and clinical management. Howie DW(1), Neale SD, Haynes DR, Holubowycz OT, McGee MA, Solomon LB, Callary SA, Atkins GJ, Findlay DM. Author information: (1)Department of Orthopaedics and...

Femoral bone loss in revision total hip arthroplasty: evaluation and management.

The Journal of the American Academy of Orthopaedic Surgeons | 2013 | Sheth NP, Nelson CL, Paprosky WG

[Indexed for MEDLINE] 6. JBJS Rev. 2023 Oct 9;11(10):e23.00105. doi: 10.2106/JBJS.RVW.23.00105. eCollection 2023 Oct 1. Metallosis in Total Hip Arthroplasty. Lee A(1), Paiement GD, Penenberg BL, Rajaee SS. Author information: (1)Department of Orthopaedic Surgery, Cedars-Sinai Medical Center, Los Angeles, California. » Metallosis is a rare but significant complication that can o...

Periprosthetic osteolysis after total hip replacement: molecular pathology and clinical management.

Inflammopharmacology | 2013 | Howie DW, Neale SD, Haynes DR, Holubowycz OT

[Indexed for MEDLINE] 16. Eur Spine J. 2025 Aug;34(8):3365-3375. doi: 10.1007/s00586-025-08926-6. Epub 2025 May 28. Patient outcomes and surgical strategies in revision cervical arthroplasty following M6-C™ disc-related osteolysis. Scott-Young M(1)(2), Nielsen D(3), Riar S(4)(3), Rathbone E(4). Author information: (1)Faculty of Health Science and Medicine, Bond University, 27 G...

Pathologic Periprosthetic Fracture After Radial Head Arthroplasty: A Report of 2 Cases.

JBJS case connector | 2022 | Ozdag Y, Foster B, Grandizio LC

[Indexed for MEDLINE] Conflict of interest statement: Disclosure: The Disclosure of Potential Conflicts of Interest forms are provided with the online version of the article (http://links.lww.com/JBJSCC/B930). 18. Oper Orthop Traumatol. 2026 Apr;38(2):104-118. doi: 10.1007/s00064-025-00900-1. Epub 2025 May 7. Combined direct anterior approach and navigation-assisted percutaneou...

Review of periprosthetic osteolysis in total joint arthroplasty: An emphasis on host factors and future directions

Journal of Orthopaedic Research | 2012 | Ryan T. Beck, Kenneth D. Illingworth, Khaled J. Saleh

AbstractPeriprosthetic osteolysis is one of the leading causes of total joint revision procedures. If allowed to progress in the absence of radiographic diagnosis and/or proper medical treatment, osteolysis may result in aseptic loosening yielding failure of the implant and the need for complex revision arthroplasty. The purpose of this review was to assess the current understa...

Patient outcomes and surgical strategies in revision cervical arthroplasty following M6-C™ disc-related osteolysis.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society | 2025 | Scott-Young M, Nielsen D, Riar S, Rathbone E

[Indexed for MEDLINE] Conflict of interest statement: Declarations. Conflict of interest: Relevant financial activities outside the submitted work, such as consultancy and royalties. Consent to publish: Informed consent was obtained from all individual participants included in the study. Ethical approval: This study was approved by the University Human Research Ethics Committee...

Radial head replacement with periprosthetic osteolysis

Radiopaedia.org | 2025 | Rory Weir

What Are the Functional, Radiographic, and Survivorship Outcomes of a Modified Cup-cage Technique for Pelvic Discontinuity?

Clinical orthopaedics and related research | 2024 | Mu W, Xu B, Wahafu T, Wang F

[Indexed for MEDLINE] Conflict of interest statement: Each author certifies that there are no commercial associations (consultancies, stock ownership, equity interest, patent/licensing arrangements, etc.) that might pose a conflict of interest in connection with the submitted article related to the author or any immediate family members. All ICMJE Conflict of Interest Forms for...

Porous Tantalum Metaphyseal Cones for Severe Femoral and Tibial Bone Defects in Revision Total Knee Arthroplasty are Reliable for Fixation at Mean 5-Year Follow-Up.

The Journal of arthroplasty | 2024 | Kayani B, Howard LC, Neufeld ME, Greidanus NV

[Indexed for MEDLINE] 14. Radiographics. 2015 Sep-Oct;35(5):1483-501. doi: 10.1148/rg.2015140216. Epub 2015 Aug 21. MR Imaging of Knee Arthroplasty Implants. Fritz J(1), Lurie B(1), Potter HG(1). Author information: (1)From the Department of Radiology and Imaging, Hospital for Special Surgery, 535 E 70th St, New York, NY 10021. Primary total knee arthroplasty is a highly effect...

Metallosis in Total Hip Arthroplasty.

JBJS reviews | 2023 | Lee A, Paiement GD, Penenberg BL, Rajaee SS

[Indexed for MEDLINE] Conflict of interest statement: Disclosure: The Disclosure of Potential Conflicts of Interest forms are provided with the online version of the article (http://links.lww.com/JBJSREV/B15). 7. Eur J Orthop Surg Traumatol. 2018 Jan;28(1):37-43. doi: 10.1007/s00590-017-2010-0. Epub 2017 Jun 28. Adventure sports and sexual freedom hip replacement: the tripolar...

PLGA nanoparticles engineering extracellular vesicles from human umbilical cord mesenchymal stem cells ameliorates polyethylene particles induced periprosthetic osteolysis.

Journal of nanobiotechnology | 2023 | Xie J, Hu Y, Su W, Chen S

[Indexed for MEDLINE] Conflict of interest statement: All other authors declare no competing interests. 12. Clin Orthop Relat Res. 2024 Dec 1;482(12):2149-2160. doi: 10.1097/CORR.0000000000003186. Epub 2024 Jul 9. What Are the Functional, Radiographic, and Survivorship Outcomes of a Modified Cup-cage Technique for Pelvic Discontinuity? Mu W(1), Xu B(1), Wahafu T(1), Wang F(1),...

MRI with state-of-the-art metal artifact reduction after total hip arthroplasty: periprosthetic findings in asymptomatic and symptomatic patients.

European radiology | 2020 | Filli L, Jungmann PM, Zingg PO, Rüdiger HA

[Indexed for MEDLINE] 20. J Arthroplasty. 1996 Aug;11(5):613-9. doi: 10.1016/s0883-5403(96)80119-7. Periprosthetic metastatic carcinoma. Pitfalls in the management of two cases initially diagnosed as osteolysis. Schmidt AH(1), Walker G, Kyle RF, Thompson RC Jr. Author information: (1)Department of Orthopedic Surgery, Hennepin County Medical Center, Minneapolis, MN 55415-1829, U...

Adventure sports and sexual freedom hip replacement: the tripolar hip.

European journal of orthopaedic surgery & traumatology : orthopedie traumatologie | 2018 | Pritchett JW

[Indexed for MEDLINE] 8. J Arthroplasty. 1998 Oct;13(7):843-5. doi: 10.1016/s0883-5403(98)90042-0. Periprosthetic acetabular fracture associated with extensive osteolysis. Chatoo M(1), Parfitt J, Pearse MF. Author information: (1)Department of Orthopaedic Surgery, Central Middlesex Hospital, London, United Kingdom. Periprosthetic fracture of the acetabulum is an uncommon compli...

Management of Periprosthetic Fractures

Orthopaedic Knowledge Online Journal | 2017

Periprosthetic Osteolysis of Total Hip Arthroplasties (THA)

Trauma and Orthopaedic Classifications | 2015 | Nikolaos K. Kanakaris, Peter V. Giannoudis

Acetabular fracture, osteolysis, and loose cup

Periprosthetic Fracture Management | 2013

What Is the Best Method to Image Periprosthetic Osteolysis Around Total Knee Arthroplasties?

JBJS Orthopaedic Highlights: Knee Surgery | 2012 | Michael A. Mont

Underappreciated benefits of erythromycin in the management of periprosthetic inflammation and osteolysis

Bone | 2010 | W. Ren, R.B. Blasier, D.C. Markel

Magnetic resonance imaging in the evaluation of periprosthetic acetabular osteolysis: A cadaveric study

Journal of Orthopaedic Research | 2005 | Daniel E. Weiland, Tim A. Walde, Serena B. Leung, Christi J. Sychterz

AbstractPeriprosthetic osteolysis is a well recognized complication of total hip arthroplasty that leads to implant failure. The ability to accurately assess and visualize the position and volume of periacetabular bone defects is paramount for clinical observation and medical treatment, as well as pre‐operative planning of revision surgery. We have developed a modified magnetic...

Magnetic resonance imaging after total hip arthroplasty: evaluation of periprosthetic soft tissue.

The Journal of bone and joint surgery. American volume | 2004 | Potter HG, Nestor BJ, Sofka CM, Ho ST

[Indexed for MEDLINE] 11. J Nanobiotechnology. 2023 Oct 31;21(1):398. doi: 10.1186/s12951-023-02177-7. PLGA nanoparticles engineering extracellular vesicles from human umbilical cord mesenchymal stem cells ameliorates polyethylene particles induced periprosthetic osteolysis. Xie J(1), Hu Y(1), Su W(2), Chen S(3), Wang J(4), Liang S(4), Chen M(3), Wang H(4), Ma T(5). Author info...

Periprosthetic acetabular fracture associated with extensive osteolysis.

The Journal of arthroplasty | 1998 | Chatoo M, Parfitt J, Pearse MF

[Indexed for MEDLINE] 9. J Am Acad Orthop Surg. 2008;16 Suppl 1:S20-5. doi: 10.5435/00124635-200800001-00006. What are the guidelines for the surgical and nonsurgical treatment of periprosthetic osteolysis? Stulberg BN(1), Della Valle AG; Implant Wear Symposium 2007 Clinical Work Group. Collaborators: Callaghan JJ, Cuckler JM, Galante JO, Della Valle AG, Goodman SB, Huddleston...

Two distinct cellular mechanisms of osteoclast formation and bone resorption in periprosthetic osteolysis

Journal of Orthopaedic Research | 2003 | A. Sabokbar, O. Kudo, N. A. Athanasou

AbstractPurpose: TNFα and IL‐1α are proinflammatory cytokines that are abundant in periprosthetic tissues. These cytokines stimulate bone resorption and have recently been shown to directly induce osteoclast formation in mouse marrow cultures. We examined whether TNFα and IL‐1α can directly induce osteoclast formation from human arthroplasty‐derived (CD14+) macrophages by a mec...

Erratum to “Pressure‐induced periprosthetic osteolysis: a rat model”

Journal of Orthopaedic Research | 2002 | Ralf Skripitz, Per Aspenberg

Periprosthetic metastatic carcinoma. Pitfalls in the management of two cases initially diagnosed as osteolysis.

The Journal of arthroplasty | 1996 | Schmidt AH, Walker G, Kyle RF, Thompson RC Jr

[Indexed for MEDLINE]

Pressure‐induced periprosthetic osteolysis: A rat model

Journal of Orthopaedic Research | 2000 | Ralf Skripitz, Per Aspenberg

AbstractRecent animal experiments have indicated that oscillating fluid pressure at the interface of bone and implant can lead to osteolysis. However, external nonphysiologic saline solutions were used to generate the pressure in these studies. In the present study on 15 Sprague‐Dawley rats, hydrostatic pressure fluctuations were applied to bone through body fluids, by compress...

Periprosthetic osteolysis

SpringerReference

Periprosthetic osteolysis

Rheumatology and Immunology Therapy