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Evidence Search

Search reputable indexed orthopaedic literature from multiple scholarly sources, classify the evidence, and link papers directly to wiki topics and cases.

Sources: PubMed, Europe PMC, Crossref

Linking results to Wiki: Osteosarcoma — Diagnosis & Treatment
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Results are classified automatically from source metadata across PubMed, Europe PMC, and Crossref.
Crossref PubMed
Crossref Review Article Evidence Moderate

Primary Cardiac Osteosarcoma: Epidemiology, Diagnosis, and Management — A Narrative Review

Orthopedic Reviews | 2025 | Tommy Li, Eric Nguyen, Jamal Hasoon, Ali Khalifa

Purpose Primary cardiac sarcomas are exceedingly rare, with a very low incidence in the general population. A variety of sarcoma subtypes can originate in the heart, including angiosarcoma, rhabdomyosarcoma, leiomyosarcoma, fibrosarcoma, and osteosarcoma. These tumors are typically classified based on histological characteristics, most often determined following surgical excisi...

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PubMed Narrative Review Evidence Moderate

Immunotherapy for osteosarcoma: Fundamental mechanism, rationale, and recent breakthroughs.

Cancer letters | 2021 | Chen C, Xie L, Ren T, Huang Y

[Indexed for MEDLINE] 3. J Am Acad Orthop Surg. 2009 Aug;17(8):515-27. doi: 10.5435/00124635-200908000-00005. Osteosarcoma. Messerschmitt PJ(1), Garcia RM, Abdul-Karim FW, Greenfield EM, Getty PJ. Author information: (1)Department of Orthopaedic Surgery, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH 44106, USA. Osteosarcoma, the most c...

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PubMed Cohort / Comparative Study Evidence Moderate

A clinical comparison between dedifferentiated low-grade osteosarcoma and conventional osteosarcoma.

The bone & joint journal | 2019 | Toki S, Kobayashi E, Yoshida A, Ogura K

[Indexed for MEDLINE] 18. Z Orthop Unfall. 2018 Feb;156(1):105-124. doi: 10.1055/s-0043-117905. Epub 2018 Feb 22. Knochensarkome. [Article in German; Abstract available in German from the publisher] Hardes J, Gosheger G, Budny T. Bone sarcomas are extremely rare representing approximately 0.2% among all cancer types. Due to the rarity of these tumors both the patients and the p...

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PubMed Narrative Review Evidence Moderate

Understanding osteosarcomas.

JAAPA : official journal of the American Academy of Physician Assistants | 2018 | Simpson E, Brown HL

[Indexed for MEDLINE] 2. Cancer Lett. 2021 Mar 1;500:1-10. doi: 10.1016/j.canlet.2020.12.024. Epub 2020 Dec 23. Immunotherapy for osteosarcoma: Fundamental mechanism, rationale, and recent breakthroughs. Chen C(1), Xie L(2), Ren T(1), Huang Y(1), Xu J(2), Guo W(3). Author information: (1)Musculoskeletal Tumor Center, Peking University People's Hospital, Beijing, 100044, People'...

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PubMed Narrative Review Evidence Moderate

Knochensarkome.

Zeitschrift fur Orthopadie und Unfallchirurgie | 2018 | Hardes J, Gosheger G, Budny T

[Indexed for MEDLINE] Conflict of interest statement: Die Autoren geben an, dass kein Interessenkonflikt besteht. 19. Int Orthop. 2017 Oct;41(10):2189-2197. doi: 10.1007/s00264-017-3499-x. Epub 2017 Jun 1. Knee joint preservation surgery in osteosarcoma using tumour-bearing bone treated with liquid nitrogen. Higuchi T(1), Yamamoto N(1), Nishida H(1), Hayashi K(1), Takeuchi A(1)...

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PubMed Narrative Review Evidence Moderate

The pharmacogenomics of osteosarcoma.

The pharmacogenomics journal | 2017 | Serra M, Hattinger CM

[Indexed for MEDLINE] 15. Pathol Oncol Res. 2016 Oct;22(4):847-52. doi: 10.1007/s12253-016-0074-5. Epub 2016 May 26. Prognostic Value of Vascular Invasion in Pediatric Osteosarcomas. Benezech S(1), Chabaud S(2), Chambon F(3), Dijoud F(4), Chotel F(4), Marec-Berard P(5). Author information: (1)Institut d'Hematologie et Oncologie Pédiatrique, 1 Place Joseph Renaut, 69008, Lyon, F...

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PubMed Case Report / Series Evidence Low

[Superficial extraskeletal osteosarcoma. Case report].

Revista medica del Instituto Mexicano del Seguro Social | 2024 | García-Esparza PE, Mantilla Morales A

[Indexed for MEDLINE] Conflict of interest statement: los autores han completado y enviado la forma traducida al español de la declaración de conflictos potenciales de interés del Comité Internacional de Editores de Revistas Médicas, y no fue reportado alguno que tuviera relación con este artículo. 11. Bone Joint J. 2019 Jun;101-B(6):739-744. doi: 10.1302/0301-620X.101B6.BJJ-20...

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PubMed Original Article Evidence Unclassified

Diagnosis and clinical outcome of cats with primary appendicular bone tumors: 76 cases.

Journal of the American Veterinary Medical Association | 2026 | Kimura S, Lubelski J, Wood CJ, Selmic LE

[Indexed for MEDLINE] 6. Orthopadie (Heidelb). 2023 Jun;52(6):509-522. doi: 10.1007/s00132-023-04387-1. Epub 2023 Jun 6. [Primary malignant bone tumors]. [Article in German; Abstract available in German from the publisher] Funovics PT(1). Author information: (1)Universitätsklinik für Orthopädie und Unfallchirurgie, Klinische Abteilung für Orthopädie, Medizinische Universität Wi...

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PubMed Narrative Review Evidence Moderate

Pediatric osteogenic sarcoma.

Current opinion in pediatrics | 2010 | Kim HJ, Chalmers PN, Morris CD

[Indexed for MEDLINE] 9. Acta Orthop. 2014 Dec;85(6):663-9. doi: 10.3109/17453674.2014.950800. Epub 2014 Aug 20. Computer-assisted surgery in orthopedic oncology. Gerbers JG(1), Stevens M, Ploegmakers JJ, Bulstra SK, Jutte PC. Author information: (1)Department of Orthopedic Surgery , University of Groningen, University Medical Center Groningen, Groningen , the Netherlands. BACK...

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PubMed Case Report / Series Evidence Low

Radiation-Associated Primary Osteosarcoma of the Breast.

Pathobiology : journal of immunopathology, molecular and cellular biology | 2020 | Bartlett H, Elghobashy M, Deshmukh N, Rao R

[Indexed for MEDLINE] 14. Pharmacogenomics J. 2017 Jan;17(1):11-20. doi: 10.1038/tpj.2016.45. Epub 2016 May 31. The pharmacogenomics of osteosarcoma. Serra M(1), Hattinger CM(1). Author information: (1)Laboratory of Experimental Oncology, Orthopaedic Rizzoli Institute, Bologna, Italy. Osteosarcoma (OS), the most common malignant tumor of bone, is presently treated with multidru...

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PubMed Narrative Review Evidence Moderate

Osteosarcoma.

The Journal of the American Academy of Orthopaedic Surgeons | 2009 | Messerschmitt PJ, Garcia RM, Abdul-Karim FW, Greenfield EM

[Indexed for MEDLINE] 4. Cancer Treat Res. 2023;185:127-139. doi: 10.1007/978-3-031-27156-4_8. Osteosarcoma and Its Advancement. Basit Q(1), Qazi HS(2), Tanveer S(3). Author information: (1)Orthopedic Sports Medicine Center, Al Mana General Hospital, Jubail, Saudi Arabia. qazibasit_cs@hotmail.com. (2)Hospital of Dalian Medical University, Dalian, Lionning, China. (3)FCPS Genera...

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Crossref Scholarly Work Evidence Unclassified

Knots in Orthopedic Surgery

Orthopaedic Sports Medicine | 2024 | Mike H. Baums

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PubMed Original Article Evidence Unclassified

Osteosarcoma and Its Advancement.

Cancer treatment and research | 2023 | Basit Q, Qazi HS, Tanveer S

[Indexed for MEDLINE] 5. J Am Vet Med Assoc. 2026 Apr 10;264(8):1005-1013. doi: 10.2460/javma.25.11.0724. Print 2026 Aug 1. Diagnosis and clinical outcome of cats with primary appendicular bone tumors: 76 cases. Kimura S(1), Lubelski J(1), Wood CJ(2), Selmic LE(3), Maritato KC(4), Morello E(5), Pellin MA(6), Oblak ML(7), Culp WTN(8), Malek S(9), Séguin B(10), Vernier T(11), Sum...

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PubMed Original Article Evidence Unclassified

[Primary malignant bone tumors].

Orthopadie (Heidelberg, Germany) | 2023 | Funovics PT

[Indexed for MEDLINE] 7. J Egypt Natl Canc Inst. 2018 Mar;30(1):7-11. doi: 10.1016/j.jnci.2018.02.001. Epub 2018 Feb 26. Osteosarcoma of the jaw: Challenges in the diagnosis and treatment. ElKordy MA(1), ElBaradie TS(2), ElSebai HI(2), KhairAlla SM(2), Amin AAE(2). Author information: (1)Department of Surgical Oncology, National Cancer Institute, Cairo University, Egypt. Electr...

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PubMed Original Article Evidence Unclassified

Pediatric Osteosarcoma: Correlation of Imaging Findings with Histopathologic Features, Treatment, and Outcome.

Radiographics : a review publication of the Radiological Society of North America, Inc | 2022 | Nguyen JC, Baghdadi S, Pogoriler J, Guariento A

[Indexed for MEDLINE] 13. Pathobiology. 2020;87(5):322-326. doi: 10.1159/000509580. Epub 2020 Sep 11. Radiation-Associated Primary Osteosarcoma of the Breast. Bartlett H(1), Elghobashy M(2), Deshmukh N(3), Rao R(4), Shaaban AM(3). Author information: (1)Department of Histopathology, Hereford County Hospital, Hereford, United Kingdom, h.bartlett2@nhs.net. (2)University of Birmin...

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PubMed Original Article Evidence Unclassified

Treatment outcome of patients with chondroblastic osteosarcoma of the limbs and pelvis.

The bone & joint journal | 2019 | Tsagozis P, Laitinen MK, Stevenson JD, Jeys LM

[Indexed for MEDLINE] 12. Radiographics. 2022 Jul-Aug;42(4):1196-1213. doi: 10.1148/rg.210171. Epub 2022 May 20. Pediatric Osteosarcoma: Correlation of Imaging Findings with Histopathologic Features, Treatment, and Outcome. Nguyen JC(1), Baghdadi S(1), Pogoriler J(1), Guariento A(1), Rajapakse CS(1), Arkader A(1). Author information: (1)From the Department of Radiology (J.C.N.,...

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Crossref Scholarly Work Evidence Unclassified

Treatment of Children with Osteosarcoma

Osteosarcoma – Diagnosis, Mechanisms, and Translational Developments | 2019 | Maxim Yu. Rykov, Elmira R. Sengapova

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PubMed Original Article Evidence Unclassified

Osteosarcoma of the jaw: Challenges in the diagnosis and treatment.

Journal of the Egyptian National Cancer Institute | 2018 | ElKordy MA, ElBaradie TS, ElSebai HI, KhairAlla SM

[Indexed for MEDLINE] 8. Curr Opin Pediatr. 2010 Feb;22(1):61-6. doi: 10.1097/MOP.0b013e328334581f. Pediatric osteogenic sarcoma. Kim HJ(1), Chalmers PN, Morris CD. Author information: (1)Hospital for Special Surgery, New York, NY, USA. kimh@hss.edu PURPOSE OF REVIEW: Osteogenic sarcoma, also known as osteosarcoma, is a primary malignancy of the bone in which spindle cells prod...

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PubMed Original Article Evidence Unclassified

Knee joint preservation surgery in osteosarcoma using tumour-bearing bone treated with liquid nitrogen.

International orthopaedics | 2017 | Higuchi T, Yamamoto N, Nishida H, Hayashi K

[Indexed for MEDLINE] 20. Br J Oral Maxillofac Surg. 1997 Oct;35(5):357-62. doi: 10.1016/s0266-4356(97)90410-1. Osteosarcoma of the jaw bones. Doval DC(1), Kumar RV, Kannan V, Sabitha KS, Misra S, Vijay Kumar M, Hegde P, Bapsy PP, Mani K, Shenoy AM, Kumarswamy SV. Author information: (1)Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bangalore, India. Ost...

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Crossref Scholarly Work Evidence Unclassified

Osteosarcoma of the Jaw: Classification, Diagnosis and Treatment

Osteosarcoma - Biology, Behavior and Mechanisms | 2017 | Daris Ferrari, Laura Moneghini, Fabiana Allevi, Gaetano Bulfamante

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PubMed Original Article Evidence Unclassified

Prognostic Value of Vascular Invasion in Pediatric Osteosarcomas.

Pathology oncology research : POR | 2016 | Benezech S, Chabaud S, Chambon F, Dijoud F

[Indexed for MEDLINE] 16. Int J Clin Oncol. 2014 Aug;19(4):731-8. doi: 10.1007/s10147-013-0592-z. Epub 2013 Jul 24. Diagnosis and treatment of low-grade osteosarcoma: experience with nine cases. Hayashi K(1), Tsuchiya H, Yamamoto N, Shirai T, Nishida H, Takeuchi A, Kimura H, Miwa S, Inatani H, Okamoto H, Yamada S, Ikeda H, Sawada-Kitamura S, Nojima T, Ooi A, Otsuka T. Author in...

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PubMed Original Article Evidence Unclassified

Computer-assisted surgery in orthopedic oncology.

Acta orthopaedica | 2014 | Gerbers JG, Stevens M, Ploegmakers JJ, Bulstra SK

[Indexed for MEDLINE] 10. Rev Med Inst Mex Seguro Soc. 2024 Mar 4;62(2):1-6. doi: 10.5281/zenodo.10712277. [Superficial extraskeletal osteosarcoma. Case report]. [Article in Spanish; Abstract available in Spanish from the publisher] García-Esparza PE(1), Mantilla Morales A(2). Author information: (1)Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospita...

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PubMed Original Article Evidence Unclassified

Diagnosis and treatment of low-grade osteosarcoma: experience with nine cases.

International journal of clinical oncology | 2014 | Hayashi K, Tsuchiya H, Yamamoto N, Shirai T

[Indexed for MEDLINE] 17. Bone Joint J. 2019 Jun;101-B(6):745-752. doi: 10.1302/0301-620X.101B6.BJJ-2018-1207.R1. A clinical comparison between dedifferentiated low-grade osteosarcoma and conventional osteosarcoma. Toki S(1), Kobayashi E(2), Yoshida A(3), Ogura K(4), Wakai S(5), Yoshimoto S(6), Yonemori K(7), Kawai A(2). Author information: (1)Department of Musculoskeletal Onco...

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PubMed Cohort / Comparative Study Evidence Moderate

Osteosarcoma of the jaw bones.

The British journal of oral & maxillofacial surgery | 1997 | Doval DC, Kumar RV, Kannan V, Sabitha KS

[Indexed for MEDLINE]

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Crossref Scholarly Work Evidence Unclassified

20 Distal Femur Osteosarcoma

Orthopaedic Oncology | 2008

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Crossref Scholarly Work Evidence Unclassified

35 Osteosarcoma of the Pelvis

Orthopaedic Oncology | 2008

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Crossref Scholarly Work Evidence Unclassified

30 Osteosarcoma of the Talus

Orthopaedic Oncology | 2008

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Crossref Scholarly Work Evidence Unclassified

5 Osteosarcoma of the Proximal Humerus

Orthopaedic Oncology | 2008

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Crossref Scholarly Work Evidence Unclassified

21 Parosteal Osteosarcoma of the Distal Femur

Orthopaedic Oncology | 2008

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Crossref Journal Article Evidence Unclassified

A Delayed Diagnosis Of Staphylococcus Aureus Infective Endocarditis In An Orthopaedic Patient

The Internet Journal of Orthopedic Surgery | 2007

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Crossref Scholarly Work Evidence Unclassified

Pediatric Orthopedic Trauma

Pediatric Trauma | 2005

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Crossref Scholarly Work Evidence Unclassified

Orthopedic Imaging

Current Orthopedic diagnosis & treatment | 2000 | J. D. Mabrey

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Crossref Scholarly Work Evidence Unclassified

Epicondylitis

Current Orthopedic diagnosis & treatment | 2000 | A. Agarwal

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Crossref Scholarly Work Evidence Unclassified

Spondylolisthesis

Current Orthopedic diagnosis & treatment | 2000 | R. Ward

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Crossref Scholarly Work Evidence Unclassified

Early Radiological Diagnosis and Differential Diagnosis of Infection in Orthopaedic Surgery

Infection and Local Treatment in Orthopedic Surgery | M. B. Gallazzi, R. Chiapparino, P. G. Garbagna

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