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Evidence Search

Search reputable indexed orthopaedic literature from multiple scholarly sources, classify the evidence, and link papers directly to wiki topics and cases.

Sources: PubMed, Europe PMC, Crossref

Linking results to Wiki: Chondrosarcoma — Grades & Surgery
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Results are classified automatically from source metadata across PubMed, Europe PMC, and Crossref.
PubMed Crossref
PubMed Narrative Review Evidence Moderate

Chondrosarcoma: Clinical behavior, molecular mechanisms, and emerging therapeutic strategies.

Critical reviews in oncology/hematology | 2026 | Agulnik M, Wilky BA, Thorpe SW, Zuckerman LM

[Indexed for MEDLINE] Conflict of interest statement: Declaration of Competing Interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: M.A.: Consultant: Aadi Bioscience, Boehringer Ingelheim, Deciphera, B.A.W.: Consultant: Aadi Bioscience, Boehringer Ingelheim, Deciphera, Inhibrx, SpringWork...

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PubMed Narrative Review Evidence Moderate

Biology and Management of High-Grade Chondrosarcoma: An Update on Targets and Treatment Options.

International journal of molecular sciences | 2023 | Tlemsani C, Larousserie F, De Percin S, Audard V

[Indexed for MEDLINE] Conflict of interest statement: The authors declare no conflict of interest. 16. Int J Cancer. 2024 Jan 15;154(2):226-240. doi: 10.1002/ijc.34694. Epub 2023 Aug 19. Twenty-year outcome of prevalence, incidence, mortality and survival rate in patients with malignant bone tumors. Xu Y(1)(2)(3), Shi F(1)(2)(3)(4), Zhang Y(1)(2)(3), Yin M(1)(2)(3)(5), Han X(1)...

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PubMed Narrative Review Evidence Moderate

Chondrosarcoma of the spine: a narrative review.

The spine journal : official journal of the North American Spine Society | 2021 | Pennington Z, Ehresman J, Pittman PD, Ahmed AK

[Indexed for MEDLINE] 10. Cancer Treat Res. 2014;162:117-30. doi: 10.1007/978-3-319-07323-1_6. Chondrosarcoma of bone. Leddy LR(1), Holmes RE. Author information: (1)Medical University of South Carolina, Charleston, SC, USA, Leddyl@musc.edu. Chondrosarcoma is a cartilage forming neoplasm, which is the second most common primary malignancy of bone. Clinicians who treat chondrosa...

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PubMed Narrative Review Evidence Moderate

Biomarkers of chondrosarcoma.

Journal of clinical pathology | 2018 | Jeong W, Kim HJ

[Indexed for MEDLINE] Conflict of interest statement: Competing interests: None declared. 2. Am Fam Physician. 2018 Aug 15;98(4):205-213. Bone Cancer: Diagnosis and Treatment Principles. Ferguson JL(1), Turner SP(2). Author information: (1)Tripler Army Medical Center, Honolulu, HI, USA. (2)Schofield Barracks, Honolulu, HI, USA. Primary bone cancers include osteosarcoma, Ewing s...

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PubMed Narrative Review Evidence Moderate

Bone Cancer: Diagnosis and Treatment Principles.

American family physician | 2018 | Ferguson JL, Turner SP

[Indexed for MEDLINE] 3. Crit Rev Oncol Hematol. 2026 Feb;218:105075. doi: 10.1016/j.critrevonc.2025.105075. Epub 2025 Dec 12. Chondrosarcoma: Clinical behavior, molecular mechanisms, and emerging therapeutic strategies. Agulnik M(1), Wilky BA(2), Thorpe SW(3), Zuckerman LM(4). Author information: (1)Department of Medicine, Division of Medical Oncology, Keck School of Medicine...

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PubMed Narrative Review Evidence Moderate

Enchondroma of the Hand: Evaluation and Management.

The Journal of the American Academy of Orthopaedic Surgeons | 2016 | Lubahn JD, Bachoura A

[Indexed for MEDLINE] 18. Int J Surg Pathol. 2024 Feb;32(1):201-205. doi: 10.1177/10668969231173379. Epub 2023 May 4. Rare Dedifferentiated Periosteal Chondrosarcoma with 11-Year Metastatic Relapse: A Case Report. Gasparro MA(1), Lee L(1), Vijayakumar G(1), Gusho CA(1), Colman MW(1), Gitelis S(1), Miller I(1)(2), Blank AT(1). Author information: (1)Department of Orthopedic Surg...

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PubMed Narrative Review Evidence Moderate

Chondrosarcomas of the head and neck.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery | 2014 | Coca-Pelaz A, Rodrigo JP, Triantafyllou A, Hunt JL

[Indexed for MEDLINE] 7. Mod Pathol. 2025 Dec;38(12):100894. doi: 10.1016/j.modpat.2025.100894. Epub 2025 Sep 19. An Integrated Clinical Genomic and Transcriptomic Subgrouping of Central Chondrosarcoma. Meijer DM(1), Venneker S(2), Ameline B(3), Erdem Z(2), Cardoso S(1), Ruano D(2), Briaire-de Bruijn IH(2), van den Akker BE(2), Wijers-Koster PM(2), Scholte CHJ(4), van Praag VM(...

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PubMed Narrative Review Evidence Moderate

Chondrosarcoma of bone.

Cancer treatment and research | 2014 | Leddy LR, Holmes RE

[Indexed for MEDLINE] 11. Bone Joint J. 2021 Mar;103-B(3):562-568. doi: 10.1302/0301-620X.103B3.BJJ-2020-1337.R1. Chondrosarcoma of the hands and feet. Kask G(1)(2), Laitinen MK(1), Stevenson J(3)(4), Evans S(3), Jeys LM(3)(5), Parry MC(3)(4). Author information: (1)Department of Orthopaedics and Traumatology, Helsinki University Hospital and University of Helsinki, Helsinki, F...

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PubMed Case Report / Series Evidence Low

Rare Dedifferentiated Periosteal Chondrosarcoma with 11-Year Metastatic Relapse: A Case Report.

International journal of surgical pathology | 2024 | Gasparro MA, Lee L, Vijayakumar G, Gusho CA

[Indexed for MEDLINE] Conflict of interest statement: Declaration of Conflicting InterestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. 19. J Neurooncol. 2023 Sep;164(2):377-386. doi: 10.1007/s11060-023-04432-1. Epub 2023 Sep 4. Management of chordoma and chondrosarcoma with definitive dose-...

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PubMed Case Report / Series Evidence Low

Chondrosarcoma of hyoid bone: a case report.

JPMA. The Journal of the Pakistan Medical Association | 2023 | Syed D, Pasha H, Ali JP, Aqil S

[Indexed for MEDLINE] 9. Spine J. 2021 Dec;21(12):2078-2096. doi: 10.1016/j.spinee.2021.04.021. Epub 2021 May 8. Chondrosarcoma of the spine: a narrative review. Pennington Z(1), Ehresman J(2), Pittman PD(3), Ahmed AK(4), Lubelski D(4), McCarthy EF(5), Goodwin CR(6), Sciubba DM(7). Author information: (1)Department of Neurosurgery, Mayo Clinic, Rochester, MN USA 55905; Departme...

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PubMed Original Article Evidence Unclassified

An Integrated Clinical Genomic and Transcriptomic Subgrouping of Central Chondrosarcoma.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc | 2025 | Meijer DM, Venneker S, Ameline B, Erdem Z

[Indexed for MEDLINE] 8. J Pak Med Assoc. 2023 Mar;73(3):668-670. doi: 10.47391/JPMA.4481. Chondrosarcoma of hyoid bone: a case report. Syed D(1), Pasha H(1), Ali JP(2), Aqil S(1). Author information: (1)Department of ENT, Liaquat National Hospital, Karachi, Pakistan. (2)Department of Histopathology, Liaquat National Hospital, Karachi, Pakistan. Chondrosarcoma of hyoid bone is...

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Crossref Journal Article Evidence Unclassified

Treatment of Bilateral Distal Femoral Shaft Fractures in a Paraplegic Patient with Intramedullary Nailing: A Case Report

Journal of Orthopaedic Case Reports | 2025 | Ernesto S Quinto Jr., Brendan J Liakos, William L Pistel

Introduction: Lower extremity fractures are a frequent complication in patients with chronic spinal cord injury due to significant bone mineral density loss and altered bone metabolism. While non-operative management has traditionally been favored, advances in surgical techniques have expanded treatment options, including intramedullary nailing and plate fixation. However, the...

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PubMed Original Article Evidence Unclassified

Twenty-year outcome of prevalence, incidence, mortality and survival rate in patients with malignant bone tumors.

International journal of cancer | 2024 | Xu Y, Shi F, Zhang Y, Yin M

[Indexed for MEDLINE] 17. J Am Acad Orthop Surg. 2016 Sep;24(9):625-33. doi: 10.5435/JAAOS-D-15-00452. Enchondroma of the Hand: Evaluation and Management. Lubahn JD(1), Bachoura A. Author information: (1)From the Department of Orthopaedic Surgery, UPMC Hamot, Erie, PA. Enchondroma is the most common primary bone tumor of the hand. This benign, cartilaginous tumor often presents...

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PubMed Original Article Evidence Unclassified

SPECT/CT Radiomics for Differentiating between Enchondroma and Grade I Chondrosarcoma.

Tomography (Ann Arbor, Mich.) | 2023 | Yoon H, Choi WH, Joo MW, Ha S

[Indexed for MEDLINE] Conflict of interest statement: The authors declare no conflict of interest. 6. Eur Arch Otorhinolaryngol. 2014 Oct;271(10):2601-9. doi: 10.1007/s00405-013-2807-3. Epub 2013 Nov 10. Chondrosarcomas of the head and neck. Coca-Pelaz A(1), Rodrigo JP, Triantafyllou A, Hunt JL, Fernández-Miranda JC, Strojan P, de Bree R, Rinaldo A, Takes RP, Ferlito A. Author...

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PubMed Narrative Review Evidence Moderate

The clinical approach towards chondrosarcoma.

The oncologist | 2008 | Gelderblom H, Hogendoorn PC, Dijkstra SD, van Rijswijk CS

[Indexed for MEDLINE] 14. J Am Acad Orthop Surg. 2000 Sep-Oct;8(5):292-304. doi: 10.5435/00124635-200009000-00003. Cartilage tumors: evaluation and treatment. Marco RA(1), Gitelis S, Brebach GT, Healey JH. Author information: (1)M.D. Anderson Cancer Center, Houston, USA. The proper treatment of cartilaginous tumors is dependent on the clinicopathologic and radiologic findings....

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PubMed Original Article Evidence Unclassified

Management of chordoma and chondrosarcoma with definitive dose-escalated single-fraction spine stereotactic radiosurgery.

Journal of neuro-oncology | 2023 | Sherry AD, Maroongroge S, De B, Amini B

[Indexed for MEDLINE] Conflict of interest statement: Dr. De reports honoraria from Sermo, Inc. Dr. Li reports research grants from BMS, Medtronic; honoraria from Monteris; and travel expenses from Elekta. Dr. Yeboa reports research grants from Brockman foundation and the MD Anderson Shirley Stein Award, MD Anderson Cancer Center. Dr. McAleer reports honoraria from PREX S. p. A...

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Crossref Journal Article Evidence Unclassified

Prognostic Factors and Surgical Impact of Non‐metastatic Conventional Chondrosarcoma of the Extremities

Orthopaedic Surgery | 2023 | Wenhui Wang, Junping Zhen

ObjectiveChondrosarcoma is a common bone malignancy, and the main treatment method is surgery. Different surgeries lead to different survival outcomes. The aim of this study was to construct a new clinical predictive tool to accurately predict the overall survival (OS) and cause specific survival (CSS) of patients with chondrosarcoma receiving different treatments.MethodsA tota...

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PubMed Original Article Evidence Unclassified

Chondrosarcoma.

The Journal of the American Academy of Orthopaedic Surgeons | 2021 | Weinschenk RC, Wang WL, Lewis VO

[Indexed for MEDLINE] 5. Tomography. 2023 Oct 16;9(5):1868-1875. doi: 10.3390/tomography9050148. SPECT/CT Radiomics for Differentiating between Enchondroma and Grade I Chondrosarcoma. Yoon H(1), Choi WH(1), Joo MW(2), Ha S(3), Chung YA(4). Author information: (1)Division of Nuclear Medicine, Department of Radiology, St. Vincent's Hospital, College of Medicine, The Catholic Univ...

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PubMed Original Article Evidence Unclassified

Chondrosarcoma of the hands and feet.

The bone & joint journal | 2021 | Kask G, Laitinen MK, Stevenson J, Evans S

[Indexed for MEDLINE] 12. Mol Cancer Ther. 2019 Nov;18(11):2021-2029. doi: 10.1158/1535-7163.MCT-18-1020. Epub 2019 Jul 24. Anti-miRNA Oligonucleotide Therapy for Chondrosarcoma. Sun X(1), Chen Y(1)(2), Yu H(1), Machan JT(1)(3)(4), Alladin A(1), Ramirez J(1), Taliano R(5), Hart J(5), Chen Q(1), Terek RM(6)(7). Author information: (1)Department of Orthopaedics, Warren Alpert Med...

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PubMed Original Article Evidence Unclassified

Anti-miRNA Oligonucleotide Therapy for Chondrosarcoma.

Molecular cancer therapeutics | 2019 | Sun X, Chen Y, Yu H, Machan JT

[Indexed for MEDLINE] Conflict of interest statement: The authors report the following potential conflicts of interest: Y. Chen and Q. Chen have ownership interest in NanoDe Therapeutics Inc. 13. Oncologist. 2008 Mar;13(3):320-9. doi: 10.1634/theoncologist.2007-0237. The clinical approach towards chondrosarcoma. Gelderblom H(1), Hogendoorn PC, Dijkstra SD, van Rijswijk CS, Krol...

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PubMed Narrative Review Evidence Moderate

Cartilage tumors: evaluation and treatment.

The Journal of the American Academy of Orthopaedic Surgeons | 2000 | Marco RA, Gitelis S, Brebach GT, Healey JH

[Indexed for MEDLINE] 15. Int J Mol Sci. 2023 Jan 10;24(2):1361. doi: 10.3390/ijms24021361. Biology and Management of High-Grade Chondrosarcoma: An Update on Targets and Treatment Options. Tlemsani C(1)(2), Larousserie F(3), De Percin S(1), Audard V(3), Hadjadj D(2), Chen J(1), Biau D(4), Anract P(4), Terris B(3), Goldwasser F(1), Pasmant E(2)(5), Boudou-Rouquette P(1)(2). Auth...

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