Evidence Search

Giant Cell Tumor of the Sacrum: A Narrative Review of Management Challenges and Modalities.

Healthcare (Basel, Switzerland) | 2026 | Alaseem A, Aldosari ZA, Alduraibi AA, Alzahrani RK

Conflict of interest statement: The authors declare no conflicts of interest. 5. Zhonghua Yi Xue Za Zhi. 2014 Dec 23;94(47):3778-83. [Meta-analysis of risk factors of recurrence in patients with giant cell tumor on extremities]. [Article in Chinese] Li R(1), Hu Y(2). Author information: (1)Department of Orthopedics, First Hospital, Jiamusi University, Heilongjiang 154002, China...

[Meta-analysis of risk factors of recurrence in patients with giant cell tumor on extremities].

Zhonghua yi xue za zhi | 2014 | Li R, Hu Y

[Indexed for MEDLINE] 6. Discov Oncol. 2024 Apr 4;15(1):103. doi: 10.1007/s12672-024-00918-0. Giant cell tumor of bone at distal radius suffered more soft tissue recurrence and ultrasonography is effective to detect the soft tissue recurrence. Cui L(1)(2), Sun Y(3), Jin T(3), Fan D(3), Liu W(4). Author information: (1)Department of Bone and Soft Tissue Oncology, Cangzhou Hospit...

A New Relevant Integrated Radiologic and Surgical Classification Scheme for Giant Cell Tumors of Bones.

Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews | 2025 | Chang YC, Pretell-Mazzini J, Temple HT, Soler R

[Indexed for MEDLINE] 14. Rev Bras Ortop. 2016 Jan 5;51(1):58-62. doi: 10.1016/j.rboe.2015.12.012. eCollection 2016 Jan-Feb. Giant-cell tumor: analysis on the importance of early diagnosis and the epidemiological profile. de Carvalho Diniz Ferraz DF(1), Torres Dos Santos CA(1), Farias Costa VH(1), Gonçalves Souza AM(1), Gomes Lima PR(1). Author information: (1)Service of Orthop...

Giant cell tumor of bone at distal radius suffered more soft tissue recurrence and ultrasonography is effective to detect the soft tissue recurrence.

Discover oncology | 2024 | Cui L, Sun Y, Jin T, Fan D

Conflict of interest statement: No benefits in any form have been or will be received from a commercial party related directly or indirectly to the subject of this manuscript. 7. Int J Surg Case Rep. 2019;61:202-206. doi: 10.1016/j.ijscr.2019.07.052. Epub 2019 Jul 26. En bloc giant cell tumor resection following direct hemiarthroplasty shoulder reconstruction-functional outcome...

En bloc giant cell tumor resection following direct hemiarthroplasty shoulder reconstruction-functional outcome: A case report.

International journal of surgery case reports | 2019 | Usman MA, Prasatia Sam AD, Wijaya M, Firdaus RM

Conflict of interest statement: No conflict of interest. 8. J Cancer Res Clin Oncol. 2023 Jul;149(8):4653-4661. doi: 10.1007/s00432-022-04348-9. Epub 2022 Oct 3. Microwave in situ inactivation in the treatment of bone giant cell tumor: a mid-term descriptive study. Jiang X(#)(1), Chen J(#)(1)(2), Zhou W(1), Zhang C(1), Wang G(1), Dong D(1), Xia P(3), Liu X(1), Xu F(1). Author i...

Twofold Expression of Receptor Tyrosine Kinase 2 (ROR2) in Giant Cell Tumors of Bone: Outcome of a Case‒Control Study.

Indian journal of surgical oncology | 2024 | S S, Nema SK, Tripathi SK, P KS

Conflict of interest statement: Conflict of InterestThe authors declare no competing interests. 13. J Am Acad Orthop Surg Glob Res Rev. 2025 Jul 17;9(7):e24.00321. doi: 10.5435/JAAOSGlobal-D-24-00321. eCollection 2025 Jul 1. A New Relevant Integrated Radiologic and Surgical Classification Scheme for Giant Cell Tumors of Bones. Chang YC(1), Pretell-Mazzini J, Temple HT, Soler R,...

Microwave in situ inactivation in the treatment of bone giant cell tumor: a mid-term descriptive study.

Journal of cancer research and clinical oncology | 2023 | Jiang X, Chen J, Zhou W, Zhang C

[Indexed for MEDLINE] Conflict of interest statement: The authors declare that they have no competing interests. 9. Arch Orthop Trauma Surg. 2001;121(1-2):83-6. doi: 10.1007/s004020000158. Treatment of stages 2 and 3 giant-cell tumor. Labs K(1), Perka C, Schmidt RG. Author information: (1)Department of Orthopaedics, Charité Hospital, Humboldt University, Berlin, Germany. karste...

Treatment of Patients Diagnosed with Giant Cell Tumor of Bone: Experience of a Philanthropic Hospital in the State of Piauí, Brazil.

Revista brasileira de ortopedia | 2022 | Aguiar LTA, Vasconcelos JBM, Ribeiro MB

Conflict of interest statement: Conflito de Interesses Os autores declaram não haver conflito de interesses. 12. Indian J Surg Oncol. 2024 Dec;15(4):694-698. doi: 10.1007/s13193-024-01965-3. Epub 2024 May 28. Twofold Expression of Receptor Tyrosine Kinase 2 (ROR2) in Giant Cell Tumors of Bone: Outcome of a Case‒Control Study. S S(1), Nema SK(2), Tripathi SK(3), P KS(1). Author...

Mid-term results of giant cell tumours with pathologic fractures around the knee: a multicentre retrospective study.

BMC musculoskeletal disorders | 2022 | Zhao L, Chen J, Hu Y, Ye Z

[Indexed for MEDLINE] Conflict of interest statement: The authors declare that they have no conflict of interest. 18. J Orthop Sci. 2022 May;27(3):681-688. doi: 10.1016/j.jos.2021.02.001. Epub 2021 Mar 5. Complications of surgery for giant cell tumor of bone in the extremities: Incidence, risk factors, management modality, and impact on functional and oncological outcomes. Mori...

Complications of surgery for giant cell tumor of bone in the extremities: Incidence, risk factors, management modality, and impact on functional and oncological outcomes.

Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association | 2022 | Morii T, Asano N, Nakayama R, Kikuta K

[Indexed for MEDLINE] Conflict of interest statement: Declaration of competing interest The authors declare that they have no conflicts of interest. 19. Int Orthop. 1993;17(2):87-92. doi: 10.1007/BF00183548. Giant cell tumour of bone. A surgical approach to grade III tumours. Rooney RJ(1), Asirvatham R, Lifeso RM, Ali MA, Parikh S. Author information: (1)Department of Orthopaed...

A new computerized tomography classification to evaluate response to Denosumab in giant cell tumors in the extremities.

Acta orthopaedica et traumatologica turcica | 2019 | Campanacci L, Sambri A, Medellin MR, Cimatti P

[Indexed for MEDLINE]

Treatment of stages 2 and 3 giant-cell tumor.

Archives of orthopaedic and trauma surgery | 2001 | Labs K, Perka C, Schmidt RG

[Indexed for MEDLINE] 10. Balkan Med J. 2016 Sep;33(5):496-503. doi: 10.5152/balkanmedj.2016.150473. Epub 2016 Sep 1. Advantages of Pressurized-Spray Cryosurgery in Giant Cell Tumors of the Bone. Dabak N(1), Göçer H(1), Çıraklı A(2). Author information: (1)Department of Orthopedic and Traumatology, Ondokuz Mayıs University School of Medicine, Samsun, Turkey. (2)Orthopedic and T...

Advantages of Pressurized-Spray Cryosurgery in Giant Cell Tumors of the Bone.

Balkan medical journal | 2016 | Dabak N, Göçer H, Çıraklı A

Conflict of interest statement: No conflict of interest was declared by the authors. 11. Rev Bras Ortop (Sao Paulo). 2022 Jul 7;57(5):802-806. doi: 10.1055/s-0042-1744498. eCollection 2022 Oct. Treatment of Patients Diagnosed with Giant Cell Tumor of Bone: Experience of a Philanthropic Hospital in the State of Piauí, Brazil. Aguiar LTA(1), Vasconcelos JBM(2), Ribeiro MB(1)(2)....

Giant-cell tumor: analysis on the importance of early diagnosis and the epidemiological profile.

Revista brasileira de ortopedia | 2016 | de Carvalho Diniz Ferraz DF, Torres Dos Santos CA, Farias Costa VH, Gonçalves Souza AM

15. J Med Assoc Thai. 2012 Sep;95 Suppl 9:S122-8. The outcomes of treatment of giant cell tumor of bone around the knee. Asavamongkolkul A(1), Eamsobhana P, Waikakul S, Phimolsarnti R. Author information: (1)Department of Orthopaedic Surgery, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand. siaas@mahidol.ac.th BACKGROUND: Giant cell tumor of bone ha...

Giant Cell Tumor of Bone

Tumors and Tumor-Like Lesions of Bone | 2015 | Ricardo K. Kalil

The outcomes of treatment of giant cell tumor of bone around the knee.

Journal of the Medical Association of Thailand = Chotmaihet thangphaet | 2012 | Asavamongkolkul A, Eamsobhana P, Waikakul S, Phimolsarnti R

[Indexed for MEDLINE] 16. Z Orthop Ihre Grenzgeb. 2003 Nov-Dec;141(6):690-8. doi: 10.1055/s-2003-812400. [Giant cell tumor of bone. An evaluation of 87 patients]. [Article in German] Tunn PU(1), Schlag PM. Author information: (1)Klinik für Chirurgie und Chirurgische Onkologie, Charité Universitätsmedizin Berlin. tunn@rrk.charite-buch.de AIM: Giant cell tumor (GCT) of bone is a...

Recurrence of giant-cell tumors of the long bones after curettage and packing with cement.

The Journal of bone and joint surgery. American volume | 1994 | O'Donnell RJ, Springfield DS, Motwani HK, Ready JE

[Indexed for MEDLINE] 3. Zhonghua Yi Xue Za Zhi (Taipei). 1997 Apr;59(4):240-7. Giant-cell tumor of bone around the knee. Fong YC(1), Chen TH, Chen WM, Lo WH. Author information: (1)Department of Orthopedics, China Medical College Hospital, Taichung, Taiwan, R.O.C. BACKGROUND: In most of the reported series, almost half of the giant-cell tumors involved the knee region. The cha...

Giant Cell Tumor Of The Second Metatarsal

The Internet Journal of Orthopedic Surgery | 2009

Giant-cell tumor of the pubic bone: A case report.

The Internet Journal of Orthopedic Surgery | 2009

Malignancy in Giant Cell Tumor (Malignant Giant Cell Tumor)

Atlas of Orthopedic Pathology | 2008 | Lester E. Wold, K. Krishnan Unni, Franklin H. Sim, Murali Sundaram

Giant cell tumor of the tendon sheath in a knee

The Internet Journal of Orthopedic Surgery | 2008

Giant Cell Tumor of Bone

Orthopedic Clinics of North America | 2006 | Robert E. Turcotte

Giant Cell Tumor Of First Metacarpal

The Internet Journal of Orthopedic Surgery | 2004

Giant cell formation through fusion of cells derived from a human giant cell tumor of tendon sheath

Journal of Orthopaedic Science | 2004 | Masami Hosaka, Masahito Hatori, Richard Smith, Shoichi Kokubun

[Giant cell tumor of bone. An evaluation of 87 patients].

Zeitschrift fur Orthopadie und ihre Grenzgebiete | 2003 | Tunn PU, Schlag PM

[Indexed for MEDLINE] 17. BMC Musculoskelet Disord. 2022 Dec 5;23(1):1061. doi: 10.1186/s12891-022-06005-1. Mid-term results of giant cell tumours with pathologic fractures around the knee: a multicentre retrospective study. Zhao L(1), Chen J(2), Hu Y(3), Ye Z(4), Tao K(5). Author information: (1)Department of Joint Surgery, Ningbo No.6 Hospital, No. 1059 East Zhongshan Road, N...

Giant cell tumor of bone.

Clinical orthopaedics and related research | 1986 | Eckardt JJ, Grogan TJ

[Indexed for MEDLINE] 2. J Bone Joint Surg Am. 1994 Dec;76(12):1827-33. doi: 10.2106/00004623-199412000-00009. Recurrence of giant-cell tumors of the long bones after curettage and packing with cement. O'Donnell RJ(1), Springfield DS, Motwani HK, Ready JE, Gebhardt MC, Mankin HJ. Author information: (1)Orthopaedic Oncology Unit, Massachusetts General Hospital, Boston 02114. The...

Giant Cell Tumor

Bone and Soft Tissue Tumors | 1999 | Mario Campanacci

Giant-cell tumor of bone around the knee.

Zhonghua yi xue za zhi = Chinese medical journal; Free China ed | 1997 | Fong YC, Chen TH, Chen WM, Lo WH

[Indexed for MEDLINE] 4. Healthcare (Basel). 2026 May 18;14(10):1381. doi: 10.3390/healthcare14101381. Giant Cell Tumor of the Sacrum: A Narrative Review of Management Challenges and Modalities. Alaseem A(1), Aldosari ZA(1), Alduraibi AA(2), Alzahrani RK(2), AlNahari AS(2), AlAqeel M(1), Alshaygy I(1). Author information: (1)Department of Orthopedic Surgery, College of Medicine...

Multicentric giant cell tumor of skeleton

Skeletal Radiology | 1995 | P. Bacchini, F. Bertoni, P. Ruggieri, M. Campanacci

Giant cell tumour of bone. A surgical approach to grade III tumours.

International orthopaedics | 1993 | Rooney RJ, Asirvatham R, Lifeso RM, Ali MA

[Indexed for MEDLINE] 20. Acta Orthop Traumatol Turc. 2019 Sep;53(5):376-380. doi: 10.1016/j.aott.2019.05.005. Epub 2019 Jun 26. A new computerized tomography classification to evaluate response to Denosumab in giant cell tumors in the extremities. Campanacci L(1), Sambri A(2), Medellin MR(3), Cimatti P(1), Errani C(1), Donati DM(1). Author information: (1)Istituto Ortopedico R...

Giant Cell Tumor

Bone and Soft Tissue Tumors | 1990 | Mario Campanacci, Franco Bertoni, Patrizia Bacchini

Giant Cell Tumor on Pagetic Bone

Bone and Soft Tissue Tumors | 1990 | Mario Campanacci, Franco Bertoni, Patrizia Bacchini

Giant Cell Tumor of Bone The Role of the Giant Cell in Orthopedic Pathology

Orthopedic Clinics of North America | 1977 | James Johnston

Giant-Cell Tumor and Chondrosarcomas: Grading, Treatment and Results (Studies of 209 and 131 Cases)

Malignant Bone Tumors | 1976 | M. Campanacci

Outcome of modular megaprosthesis in management of Campanacci Stage III Giant cell tumor around the knee - A Prospective Study

Journal unavailable | Ritwika Nandi, Pinaki Das, Sujit Narayan Nandi

Abstract Purpose : Juxta articular giant cell tumors around the knee constitute 50-60% of the total cases reported. If the disease is detected at an advanced stage, where it has already spread to extraosseous compartment or joint with pathological fractures, reconstruction of the joint after tumor excision poses problems and has poor functional outcome. In this article the func...