Orthonotes
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Evidence Search

Search reputable indexed orthopaedic literature from multiple scholarly sources, classify the evidence, and link papers directly to wiki topics and cases.

Sources: PubMed, Europe PMC, Crossref

Linking results to Wiki: Giant Cell Tumor — Campanacci Classification
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Results are classified automatically from source metadata across PubMed, Europe PMC, and Crossref.
PubMed Crossref
PubMed Systematic Review / Meta-analysis Evidence High

[Meta-analysis of risk factors of recurrence in patients with giant cell tumor on extremities].

Zhonghua yi xue za zhi | 2014 | Li R, Hu Y

[Indexed for MEDLINE] 5. Int Orthop. 1993;17(2):87-92. doi: 10.1007/BF00183548. Giant cell tumour of bone. A surgical approach to grade III tumours. Rooney RJ(1), Asirvatham R, Lifeso RM, Ali MA, Parikh S. Author information: (1)Department of Orthopaedic Surgery, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia. Thirty-one patients with giant cell tumou...

PubMed Original Article Evidence Unclassified

Periacetabular Resection for Bone Tumors: Is There Still a Role for Massive Allograft-prosthesis Composite Reconstructions?

Clinical orthopaedics and related research | 2026 | Scanferla R, Rajan S, Scolari F, Maccauro L

[Indexed for MEDLINE] Conflict of interest statement: Each author certifies that there are no funding or commercial associations (consultancies, stock ownership, equity interest, patent/licensing arrangements, etc.) that might pose a conflict of interest in connection with the submitted article related to the author or any immediate family members. All ICMJE Conflict of Interes...

PubMed Case Report / Series Evidence Low

En bloc giant cell tumor resection following direct hemiarthroplasty shoulder reconstruction-functional outcome: A case report.

International journal of surgery case reports | 2019 | Usman MA, Prasatia Sam AD, Wijaya M, Firdaus RM

Conflict of interest statement: No conflict of interest. 3. Balkan Med J. 2016 Sep;33(5):496-503. doi: 10.5152/balkanmedj.2016.150473. Epub 2016 Sep 1. Advantages of Pressurized-Spray Cryosurgery in Giant Cell Tumors of the Bone. Dabak N(1), Göçer H(1), Çıraklı A(2). Author information: (1)Department of Orthopedic and Traumatology, Ondokuz Mayıs University School of Medicine, S...

PubMed Original Article Evidence Unclassified

Twofold Expression of Receptor Tyrosine Kinase 2 (ROR2) in Giant Cell Tumors of Bone: Outcome of a Case‒Control Study.

Indian journal of surgical oncology | 2024 | S S, Nema SK, Tripathi SK, P KS

Conflict of interest statement: Conflict of InterestThe authors declare no competing interests. 9. Rev Esp Cir Ortop Traumatol. 2015 Jan-Feb;59(1):59-65. doi: 10.1016/j.recot.2014.06.005. Epub 2014 Aug 21. [Giant cell tumour of bone: a series of 97 cases with a mean follow-up of 12 years]. [Article in Spanish] Abat F(1), Almenara M(1), Peiró A(2), Trullols L(1), Bagué S(3), Grá...

PubMed Original Article Evidence Unclassified

Giant cell tumor of bone at distal radius suffered more soft tissue recurrence and ultrasonography is effective to detect the soft tissue recurrence.

Discover oncology | 2024 | Cui L, Sun Y, Jin T, Fan D

Conflict of interest statement: No benefits in any form have been or will be received from a commercial party related directly or indirectly to the subject of this manuscript. 15. Rev Bras Ortop (Sao Paulo). 2022 Jul 7;57(5):802-806. doi: 10.1055/s-0042-1744498. eCollection 2022 Oct. Treatment of Patients Diagnosed with Giant Cell Tumor of Bone: Experience of a Philanthropic Ho...

PubMed Original Article Evidence Unclassified

Microwave in situ inactivation in the treatment of bone giant cell tumor: a mid-term descriptive study.

Journal of cancer research and clinical oncology | 2023 | Jiang X, Chen J, Zhou W, Zhang C

[Indexed for MEDLINE] Conflict of interest statement: The authors declare that they have no competing interests. 17. J Med Assoc Thai. 2012 Sep;95 Suppl 9:S122-8. The outcomes of treatment of giant cell tumor of bone around the knee. Asavamongkolkul A(1), Eamsobhana P, Waikakul S, Phimolsarnti R. Author information: (1)Department of Orthopaedic Surgery, Faculty of Medicine, Sir...

PubMed Original Article Evidence Unclassified

Mid-term results of giant cell tumours with pathologic fractures around the knee: a multicentre retrospective study.

BMC musculoskeletal disorders | 2022 | Zhao L, Chen J, Hu Y, Ye Z

[Indexed for MEDLINE] Conflict of interest statement: The authors declare that they have no conflict of interest. 7. Acta Orthop Traumatol Turc. 2019 Sep;53(5):376-380. doi: 10.1016/j.aott.2019.05.005. Epub 2019 Jun 26. A new computerized tomography classification to evaluate response to Denosumab in giant cell tumors in the extremities. Campanacci L(1), Sambri A(2), Medellin M...

PubMed Original Article Evidence Unclassified

Treatment of Patients Diagnosed with Giant Cell Tumor of Bone: Experience of a Philanthropic Hospital in the State of Piauí, Brazil.

Revista brasileira de ortopedia | 2022 | Aguiar LTA, Vasconcelos JBM, Ribeiro MB

Conflict of interest statement: Conflito de Interesses Os autores declaram não haver conflito de interesses. 16. J Cancer Res Clin Oncol. 2023 Jul;149(8):4653-4661. doi: 10.1007/s00432-022-04348-9. Epub 2022 Oct 3. Microwave in situ inactivation in the treatment of bone giant cell tumor: a mid-term descriptive study. Jiang X(#)(1), Chen J(#)(1)(2), Zhou W(1), Zhang C(1), Wang G...

PubMed Original Article Evidence Unclassified

A new computerized tomography classification to evaluate response to Denosumab in giant cell tumors in the extremities.

Acta orthopaedica et traumatologica turcica | 2019 | Campanacci L, Sambri A, Medellin MR, Cimatti P

[Indexed for MEDLINE] 8. Indian J Surg Oncol. 2024 Dec;15(4):694-698. doi: 10.1007/s13193-024-01965-3. Epub 2024 May 28. Twofold Expression of Receptor Tyrosine Kinase 2 (ROR2) in Giant Cell Tumors of Bone: Outcome of a Case‒Control Study. S S(1), Nema SK(2), Tripathi SK(3), P KS(1). Author information: (1)Jawaharlal Institute of Postgraduate Medical Education and Research, Pon...

PubMed Original Article Evidence Unclassified

Advantages of Pressurized-Spray Cryosurgery in Giant Cell Tumors of the Bone.

Balkan medical journal | 2016 | Dabak N, Göçer H, Çıraklı A

Conflict of interest statement: No conflict of interest was declared by the authors. 4. Zhonghua Yi Xue Za Zhi. 2014 Dec 23;94(47):3778-83. [Meta-analysis of risk factors of recurrence in patients with giant cell tumor on extremities]. [Article in Chinese] Li R(1), Hu Y(2). Author information: (1)Department of Orthopedics, First Hospital, Jiamusi University, Heilongjiang 154002...

PubMed Original Article Evidence Unclassified

Giant-cell tumor: analysis on the importance of early diagnosis and the epidemiological profile.

Revista brasileira de ortopedia | 2016 | de Carvalho Diniz Ferraz DF, Torres Dos Santos CA, Farias Costa VH, Gonçalves Souza AM

19. Arch Orthop Trauma Surg. 2001;121(1-2):83-6. doi: 10.1007/s004020000158. Treatment of stages 2 and 3 giant-cell tumor. Labs K(1), Perka C, Schmidt RG. Author information: (1)Department of Orthopaedics, Charité Hospital, Humboldt University, Berlin, Germany. karsten.labs@charite.de During the period from August 1986 to August 1992, we treated 23 patients with giant cell tumo...

PubMed Cohort / Comparative Study Evidence Moderate

Treatment of stages 2 and 3 giant-cell tumor.

Archives of orthopaedic and trauma surgery | 2001 | Labs K, Perka C, Schmidt RG

[Indexed for MEDLINE] 20. Z Orthop Ihre Grenzgeb. 2003 Nov-Dec;141(6):690-8. doi: 10.1055/s-2003-812400. [Giant cell tumor of bone. An evaluation of 87 patients]. [Article in German] Tunn PU(1), Schlag PM. Author information: (1)Klinik für Chirurgie und Chirurgische Onkologie, Charité Universitätsmedizin Berlin. tunn@rrk.charite-buch.de AIM: Giant cell tumor (GCT) of bone is a...

PubMed Original Article Evidence Unclassified

[Giant cell tumour of bone: a series of 97 cases with a mean follow-up of 12 years].

Revista espanola de cirugia ortopedica y traumatologia | 2015 | Abat F, Almenara M, Peiró A, Trullols L

[Indexed for MEDLINE] 10. Clin Orthop Relat Res. 1986 Mar;(204):45-58. Giant cell tumor of bone. Eckardt JJ, Grogan TJ. Giant cell tumor GCT of bone remains a difficult and challenging management problem because there are no absolute clinical, radiographic, or histologic parameters that accurately predict the tendency of any single lesion to recur or metastasize. Enneking's and...

PubMed Original Article Evidence Unclassified

GCT: What happened after 10 years of curettage and cement? Retrospective study of 46 cases.

Acta ortopedica brasileira | 2014 | Baptista AM, Camargo AF, Caiero MT, Rebolledo DC

Conflict of interest statement: All the authors declare that there is no potential conflict of interest referring to this article. 12. Clin Orthop Relat Res. 2026 Apr 1;484(4):653-667. doi: 10.1097/CORR.0000000000003754. Epub 2025 Nov 25. Periacetabular Resection for Bone Tumors: Is There Still a Role for Massive Allograft-prosthesis Composite Reconstructions? Scanferla R(1), R...

PubMed Original Article Evidence Unclassified

The outcomes of treatment of giant cell tumor of bone around the knee.

Journal of the Medical Association of Thailand = Chotmaihet thangphaet | 2012 | Asavamongkolkul A, Eamsobhana P, Waikakul S, Phimolsarnti R

[Indexed for MEDLINE] 18. Rev Bras Ortop. 2016 Jan 5;51(1):58-62. doi: 10.1016/j.rboe.2015.12.012. eCollection 2016 Jan-Feb. Giant-cell tumor: analysis on the importance of early diagnosis and the epidemiological profile. de Carvalho Diniz Ferraz DF(1), Torres Dos Santos CA(1), Farias Costa VH(1), Gonçalves Souza AM(1), Gomes Lima PR(1). Author information: (1)Service of Orthop...

PubMed Narrative Review Evidence Moderate

Recurrence of giant-cell tumors of the long bones after curettage and packing with cement.

The Journal of bone and joint surgery. American volume | 1994 | O'Donnell RJ, Springfield DS, Motwani HK, Ready JE

[Indexed for MEDLINE] 2. Int J Surg Case Rep. 2019;61:202-206. doi: 10.1016/j.ijscr.2019.07.052. Epub 2019 Jul 26. En bloc giant cell tumor resection following direct hemiarthroplasty shoulder reconstruction-functional outcome: A case report. Usman MA(1), Prasatia Sam AD(2), Wijaya M(3), Firdaus RM(4), Yudha K(5). Author information: (1)Consultant of Orthopaedic and Traumatolog...

PubMed Narrative Review Evidence Moderate

Giant cell tumor of bone.

Clinical orthopaedics and related research | 1986 | Eckardt JJ, Grogan TJ

[Indexed for MEDLINE] 11. Acta Ortop Bras. 2014;22(6):308-11. doi: 10.1590/1413-78522014220600973. GCT: What happened after 10 years of curettage and cement? Retrospective study of 46 cases. Baptista AM(1), Camargo AF(1), Caiero MT(1), Rebolledo DC(1), Correia LF(1), de Camargo OP(1). Author information: (1)Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas...

PubMed Original Article Evidence Unclassified

Giant-cell tumor of bone around the knee.

Zhonghua yi xue za zhi = Chinese medical journal; Free China ed | 1997 | Fong YC, Chen TH, Chen WM, Lo WH

[Indexed for MEDLINE] 14. Discov Oncol. 2024 Apr 4;15(1):103. doi: 10.1007/s12672-024-00918-0. Giant cell tumor of bone at distal radius suffered more soft tissue recurrence and ultrasonography is effective to detect the soft tissue recurrence. Cui L(1)(2), Sun Y(3), Jin T(3), Fan D(3), Liu W(4). Author information: (1)Department of Bone and Soft Tissue Oncology, Cangzhou Hospi...

PubMed Original Article Evidence Unclassified

Giant cell tumour of bone. A surgical approach to grade III tumours.

International orthopaedics | 1993 | Rooney RJ, Asirvatham R, Lifeso RM, Ali MA

[Indexed for MEDLINE] 6. BMC Musculoskelet Disord. 2022 Dec 5;23(1):1061. doi: 10.1186/s12891-022-06005-1. Mid-term results of giant cell tumours with pathologic fractures around the knee: a multicentre retrospective study. Zhao L(1), Chen J(2), Hu Y(3), Ye Z(4), Tao K(5). Author information: (1)Department of Joint Surgery, Ningbo No.6 Hospital, No. 1059 East Zhongshan Road, Ni...

Crossref Scholarly Work Evidence Unclassified

Outcome of modular megaprosthesis in management of Campanacci Stage III Giant cell tumor around the knee - A Prospective Study

Journal unavailable | Ritwika Nandi, Pinaki Das, Sujit Narayan Nandi

Abstract Purpose : Juxta articular giant cell tumors around the knee constitute 50-60% of the total cases reported. If the disease is detected at an advanced stage, where it has already spread to extraosseous compartment or joint with pathological fractures, reconstruction of the joint after tumor excision poses problems and has poor functional outcome. In this article the func...