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Evidence Search

Search reputable indexed orthopaedic literature from multiple scholarly sources, classify the evidence, and link papers directly to wiki topics and cases.

Sources: PubMed, Europe PMC, Crossref

Linking results to Wiki: Antibiotic Prophylaxis in Orthopaedics
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Results are classified automatically from source metadata across PubMed, Europe PMC, and Crossref.
PubMed Crossref
PubMed Guideline / Consensus Evidence High

Controversies in orthopaedic oncology.

The bone & joint journal | 2024 | Jeys LM, Thorkildsen J, Kurisunkal V, Puri A

[Indexed for MEDLINE] Conflict of interest statement: A. Puri is a member of the editorial board of The Bone & Joint Journal. P. Ruggieri reports consulting fees from Exactech and Stryker, unrelated to this study. M. T. Houdek reports consulting fees from Link Orthopedics, unrelated to this study. E. Botello reports consulting fees, payment or honoraria for lectures, presentati...

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PubMed Guideline / Consensus Evidence High

European Society of Clinical Microbiology and Infectious Diseases/European Committee on infection control clinical guidelines on pre-operative decolonization and targeted prophylaxis in patients colonized by multidrug-resistant Gram-positive bacteria befo

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases | 2024 | Righi E, Mutters NT, Guirao X, Dolores Del Toro M

[Indexed for MEDLINE] 8. Orthopadie (Heidelb). 2025 Apr;54(4):253-260. doi: 10.1007/s00132-025-04611-0. Epub 2025 Feb 19. [Perioperative antibiotic prophylaxis in obesity]. [Article in German; Abstract available in German from the publisher] Schnurr C(1). Author information: (1)St. Vinzenz-Krankenhaus Düsseldorf, Schloßstraße 85, 40477, Düsseldorf, Deutschland. christoph.schnur...

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PubMed Systematic Review / Meta-analysis Evidence High

Antibiotic Prophylaxis for Orthopaedic Implant Removal: What Does the Evidence Say?

Current drug safety | 2023 | Rather IIG, Shafiq N, Pandey AK, Bhandari RK

[Indexed for MEDLINE] 14. Lakartidningen. 2019 Oct 21;116:FR6C. [Treatment of orthopedic implant-associated infections]. [Article in Swedish] Tevell S(1), Christensson B(2), Nilsdotter-Augustinsson Å(3), Rydén C(4), Ryding U(5), Söderquist B(6), Åkerlund B(7). Author information: (1)Infektionskliniken, Centralsjukhuset i Karlstad - Centrum för Klinisk Forskning, Region Värmland...

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PubMed Systematic Review / Meta-analysis Evidence High

Prophylactic postoperative measures to minimize surgical site infections in spine surgery: systematic review and evidence summary.

The spine journal : official journal of the North American Spine Society | 2020 | Tan T, Lee H, Huang MS, Rutges J

[Indexed for MEDLINE] 12. Infect Dis Clin North Am. 2025 Sep;39(3):383-398. doi: 10.1016/j.idc.2025.02.016. Epub 2025 Apr 4. Preventing Orthopedic Infections. Ritter AS(1), Mears S(2). Author information: (1)Division of Infectious Diseases and Global Medicine, University of Florida, 2000 Southwest Archer Road, Gainesville, FL 32610, USA. Electronic address: Alaina.Ritter@medici...

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PubMed Narrative Review Evidence Moderate

Optimizing Antibiotic Therapy in Musculoskeletal Infections.

Infectious disease clinics of North America | 2025 | Cortés-Penfield NW, Justo JA, McCreary EK, Ryder JH

[Indexed for MEDLINE] 6. Orthopedics. 2015 Nov;38(11):e1025-33. doi: 10.3928/01477447-20151020-12. Acute Management of Open Fractures: An Evidence-Based Review. Halawi MJ, Morwood MP. Open fractures are complex injuries associated with high morbidity and mortality. Despite advances made in fracture care and infection prevention, open fractures remain a therapeutic challenge wit...

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PubMed Narrative Review Evidence Moderate

[Perioperative antibiotic prophylaxis in obesity].

Orthopadie (Heidelberg, Germany) | 2025 | Schnurr C

[Indexed for MEDLINE] Conflict of interest statement: Einhaltung ethischer Richtlinien. Interessenkonflikt: C. Schnurr gibt Beratertätigkeiten für Stryker und ZimmerBiomet an. Für diesen Beitrag wurden von den Autor/-innen keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien. 9. Injury. 2019 J...

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PubMed Narrative Review Evidence Moderate

Preventing Orthopedic Infections.

Infectious disease clinics of North America | 2025 | Ritter AS, Mears S

[Indexed for MEDLINE] Conflict of interest statement: Disclosure The authors have nothing to disclose. No funding source was used for this article. 13. Curr Drug Saf. 2023;18(1):116-120. doi: 10.2174/1574886317666220429081207. Antibiotic Prophylaxis for Orthopaedic Implant Removal: What Does the Evidence Say? Rather IIG(1), Shafiq N(1), Pandey AK(1), Bhandari RK(1), Malhotra S(...

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PubMed Narrative Review Evidence Moderate

Prophylactic antibiotics for massive endoprostheses in orthopaedic oncology.

The bone & joint journal | 2023 | Azamgarhi T, Warren S, Fouch S, Standing JF

[Indexed for MEDLINE] Conflict of interest statement: The authors declare no competing interests. J. F. Standing reports research grants from the Medical Research Council (MRC), the Wellcome Trust, National Institute for Health and Care Research (NIHR), and Great Ormond Street Hospital (GOSH), consulting fees paid to their institution from Adrenomed, Proveca, and ClinSearch, an...

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PubMed Narrative Review Evidence Moderate

Antibiotic prophylaxis in orthopedics-traumatology.

Orthopaedics & traumatology, surgery & research : OTSR | 2021 | Gaudias J

[Indexed for MEDLINE] 2. J Am Acad Orthop Surg. 2020 Apr 15;28(8):309-315. doi: 10.5435/JAAOS-D-18-00193. Antibiotic Prophylaxis in Open Fractures: Evidence, Evolving Issues, and Recommendations. Garner MR(1), Sethuraman SA, Schade MA, Boateng H. Author information: (1)From the Department of Orthopaedic Trauma (Dr. Garner, Dr. Boateng), Penn State College of Medicine, Milton S....

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PubMed Narrative Review Evidence Moderate

Antibiotic Prophylaxis in Open Fractures: Evidence, Evolving Issues, and Recommendations.

The Journal of the American Academy of Orthopaedic Surgeons | 2020 | Garner MR, Sethuraman SA, Schade MA, Boateng H

[Indexed for MEDLINE] 3. J Orthop Trauma. 2015 Dec;29 Suppl 12:S19-23. doi: 10.1097/BOT.0000000000000461. Infection in Orthopaedics. Cook GE(1), Markel DC, Ren W, Webb LX, McKee MD, Schemitsch EH. Author information: (1)*Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, Canada; †Division of Orthopaedic Surgery, Department of Surgery, St....

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PubMed Narrative Review Evidence Moderate

Pin tract infection prophylaxis and treatment.

Injury | 2019 | Guerado E, Cano JR, Fernandez-Sanchez F

[Indexed for MEDLINE] 10. J Am Acad Orthop Surg. 2017 Feb;25 Suppl 1:S4-S6. doi: 10.5435/JAAOS-D-16-00634. Orthopaedic Infection: Prevention and Diagnosis. Perry KI(1), Hanssen AD. Author information: (1)From the Mayo Clinic, Rochester, MN. Host optimization, reduction of bacteria, and establishing proper wound environment in the preoperative, intraoperative, and postoperative...

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PubMed Narrative Review Evidence Moderate

[Treatment of orthopedic implant-associated infections].

Lakartidningen | 2019 | Tevell S, Christensson B, Nilsdotter-Augustinsson Å, Rydén C

[Indexed for MEDLINE] 15. J Am Acad Orthop Surg. 2018 Sep 1;26(17):e371-e378. doi: 10.5435/JAAOS-D-17-00003. Use of Intrawound Antibiotics in Orthopaedic Surgery. Chen AF(1), Fleischman A, Austin MS. Author information: (1)From the Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (Dr. Chen) and the Rothman Institute, Philadelph...

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PubMed Narrative Review Evidence Moderate

Use of Intrawound Antibiotics in Orthopaedic Surgery.

The Journal of the American Academy of Orthopaedic Surgeons | 2018 | Chen AF, Fleischman A, Austin MS

[Indexed for MEDLINE] 16. Bone Joint J. 2023 Aug 1;105-B(8):850-856. doi: 10.1302/0301-620X.105B8.BJJ-2022-1418.R1. Prophylactic antibiotics for massive endoprostheses in orthopaedic oncology. Azamgarhi T(1), Warren S(2), Fouch S(3), Standing JF(4), Gerrand C(5). Author information: (1)Pharmacy Department, Royal National Orthopaedic Hospital NHS Trust, London, UK. (2)Bone Infec...

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PubMed Narrative Review Evidence Moderate

Orthopaedic Infection: Prevention and Diagnosis.

The Journal of the American Academy of Orthopaedic Surgeons | 2017 | Perry KI, Hanssen AD

[Indexed for MEDLINE] 11. Spine J. 2020 Mar;20(3):435-447. doi: 10.1016/j.spinee.2019.09.013. Epub 2019 Sep 23. Prophylactic postoperative measures to minimize surgical site infections in spine surgery: systematic review and evidence summary. Tan T(1), Lee H(1), Huang MS(2), Rutges J(3), Marion TE(4), Mathew J(5), Fitzgerald M(5), Gonzalvo A(6), Hunn MK(2), Kwon BK(7), Dvorak M...

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PubMed Narrative Review Evidence Moderate

Prevention of Infection in Orthopedic Prosthetic Surgery.

Infectious disease clinics of North America | 2017 | Chirca I, Marculescu C

[Indexed for MEDLINE] 18. J Am Board Fam Med. 2016 Jul-Aug;29(4):500-7. doi: 10.3122/jabfm.2016.04.150386. Antibiotic Prophylaxis for Patients with a History of Total Joint Replacement. DeFroda SF(1), Lamin E(2), Gil JA(2), Sindhu K(2), Ritterman S(2). Author information: (1)From the Department of Orthopaedics, Alpert Medical School, Brown University, Providence, RI (SFD, JAG,...

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PubMed Narrative Review Evidence Moderate

Antibiotic Prophylaxis for Patients with a History of Total Joint Replacement.

Journal of the American Board of Family Medicine : JABFM | 2016 | DeFroda SF, Lamin E, Gil JA, Sindhu K

[Indexed for MEDLINE] 19. Expert Rev Med Devices. 2007 Jan;4(1):55-64. doi: 10.1586/17434440.4.1.55. Selfprotective smart orthopedic implants. Parvizi J(1), Antoci V Jr, Hickok NJ, Shapiro IM. Author information: (1)Thomas Jefferson University, Rothman Institute of Orthopedics, 925 Chestnut Street, Philadelphia, PA 19107, USA. parvj@aol.com In this review, we discuss current ad...

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PubMed Narrative Review Evidence Moderate

Infection in Orthopaedics.

Journal of orthopaedic trauma | 2015 | Cook GE, Markel DC, Ren W, Webb LX

[Indexed for MEDLINE] 4. Bone Joint J. 2024 May 1;106-B(5):425-429. doi: 10.1302/0301-620X.106B5.BJJ-2023-1381. Controversies in orthopaedic oncology. Jeys LM(1), Thorkildsen J(2), Kurisunkal V(1), Puri A(3), Ruggieri P(4), Houdek MT(5), Boyle RA(6), Ebeid W(7), Botello E(8), Morris GV(1); BOOM Consensus Scientific Committee; Laitinen MK(9); BOOM Consensus Scientific Committee....

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PubMed Narrative Review Evidence Moderate

Acute Management of Open Fractures: An Evidence-Based Review.

Orthopedics | 2015 | Halawi MJ, Morwood MP

[Indexed for MEDLINE] 7. Clin Microbiol Infect. 2024 Dec;30(12):1537-1550. doi: 10.1016/j.cmi.2024.07.012. Epub 2024 Aug 21. European Society of Clinical Microbiology and Infectious Diseases/European Committee on infection control clinical guidelines on pre-operative decolonization and targeted prophylaxis in patients colonized by multidrug-resistant Gram-positive bacteria befo...

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PubMed Narrative Review Evidence Moderate

Selfprotective smart orthopedic implants.

Expert review of medical devices | 2007 | Parvizi J, Antoci V Jr, Hickok NJ, Shapiro IM

[Indexed for MEDLINE] 20. J Am Acad Orthop Surg. 2008 May;16(5):283-93. doi: 10.5435/00124635-200805000-00007. Prophylactic antibiotics in orthopaedic surgery. Prokuski L(1). Author information: (1)University of Wisconsin Hospitals, Madison, WI 53792, USA. The use of prophylactic antibiotics in orthopaedic surgery is effective in reducing surgical site infections in hip and kne...

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Crossref Journal Article Evidence Unclassified

Antibiotic prophylaxis in veterinary orthopaedic surgery

Veterinary and Comparative Orthopaedics and Traumatology | 2001 | S. C. Budsberg, J. A. Kirsch

Antibiotic prophylaxis is widespread in veterinary and human surgery. Key principles must be followed in case selection, drug choice and administration to ensure maximal effectiveness. More prospective clinical trials in veterinary orthopaedics are needed to better define which patients and which procedures will benefit from antimicrobial prophylaxis.

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