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Evidence Search

Search reputable indexed orthopaedic literature from multiple scholarly sources, classify the evidence, and link papers directly to wiki topics and cases.

Sources: PubMed, Europe PMC, Crossref

Linking results to Wiki: Antibiotic Prophylaxis in Orthopaedics
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Results are classified automatically from source metadata across PubMed, Europe PMC, and Crossref.
PubMed Crossref
PubMed Guideline / Consensus Evidence High

European Society of Clinical Microbiology and Infectious Diseases/European Committee on infection control clinical guidelines on pre-operative decolonization and targeted prophylaxis in patients colonized by multidrug-resistant Gram-positive bacteria befo

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases | 2024 | Righi E, Mutters NT, Guirao X, Dolores Del Toro M

[Indexed for MEDLINE] 5. J Orthop Trauma. 2015 Dec;29 Suppl 12:S19-23. doi: 10.1097/BOT.0000000000000461. Infection in Orthopaedics. Cook GE(1), Markel DC, Ren W, Webb LX, McKee MD, Schemitsch EH. Author information: (1)*Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, Canada; †Division of Orthopaedic Surgery, Department of Surgery, St....

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PubMed Guideline / Consensus Evidence High

Controversies in orthopaedic oncology.

The bone & joint journal | 2024 | Jeys LM, Thorkildsen J, Kurisunkal V, Puri A

[Indexed for MEDLINE] Conflict of interest statement: A. Puri is a member of the editorial board of The Bone & Joint Journal. P. Ruggieri reports consulting fees from Exactech and Stryker, unrelated to this study. M. T. Houdek reports consulting fees from Link Orthopedics, unrelated to this study. E. Botello reports consulting fees, payment or honoraria for lectures, presentati...

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PubMed Systematic Review / Meta-analysis Evidence High

Prophylactic postoperative measures to minimize surgical site infections in spine surgery: systematic review and evidence summary.

The spine journal : official journal of the North American Spine Society | 2020 | Tan T, Lee H, Huang MS, Rutges J

[Indexed for MEDLINE] 7. Bone Joint J. 2024 May 1;106-B(5):425-429. doi: 10.1302/0301-620X.106B5.BJJ-2023-1381. Controversies in orthopaedic oncology. Jeys LM(1), Thorkildsen J(2), Kurisunkal V(1), Puri A(3), Ruggieri P(4), Houdek MT(5), Boyle RA(6), Ebeid W(7), Botello E(8), Morris GV(1); BOOM Consensus Scientific Committee; Laitinen MK(140); BOOM Consensus Scientific Committe...

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PubMed Narrative Review Evidence Moderate

Optimizing Antibiotic Therapy in Musculoskeletal Infections.

Infectious disease clinics of North America | 2025 | Cortés-Penfield NW, Justo JA, McCreary EK, Ryder JH

[Indexed for MEDLINE] 4. Clin Microbiol Infect. 2024 Dec;30(12):1537-1550. doi: 10.1016/j.cmi.2024.07.012. Epub 2024 Aug 21. European Society of Clinical Microbiology and Infectious Diseases/European Committee on infection control clinical guidelines on pre-operative decolonization and targeted prophylaxis in patients colonized by multidrug-resistant Gram-positive bacteria befo...

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PubMed Narrative Review Evidence Moderate

Preventing Orthopedic Infections.

Infectious disease clinics of North America | 2025 | Ritter AS, Mears S

[Indexed for MEDLINE] Conflict of interest statement: Disclosure The authors have nothing to disclose. No funding source was used for this article. 9. Surg Infect (Larchmt). 2022 Aug;23(6):583-589. doi: 10.1089/sur.2022.033. Pathogens and Shift of Resistance in Early Infections after Operative Fracture Fixation. Oberhuber-Kurth LM(1), Angeli R(2), Lippmann N(3), Notov D(1), Ost...

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Crossref Review Article Evidence Moderate

Enhancing Surgical Outcomes: A Critical Review of Antibiotic Prophylaxis in Orthopedic Surgery

Cureus | 2023 | Gaurav K Upadhyyaya, Sachchidanand Tewari

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PubMed Narrative Review Evidence Moderate

Antibiotic prophylaxis in orthopedics-traumatology.

Orthopaedics & traumatology, surgery & research : OTSR | 2021 | Gaudias J

[Indexed for MEDLINE] 2. J Am Acad Orthop Surg. 2020 Apr 15;28(8):309-315. doi: 10.5435/JAAOS-D-18-00193. Antibiotic Prophylaxis in Open Fractures: Evidence, Evolving Issues, and Recommendations. Garner MR(1), Sethuraman SA, Schade MA, Boateng H. Author information: (1)From the Department of Orthopaedic Trauma (Dr. Garner, Dr. Boateng), Penn State College of Medicine, Milton S....

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PubMed Narrative Review Evidence Moderate

Antibiotic Prophylaxis in Open Fractures: Evidence, Evolving Issues, and Recommendations.

The Journal of the American Academy of Orthopaedic Surgeons | 2020 | Garner MR, Sethuraman SA, Schade MA, Boateng H

[Indexed for MEDLINE] 3. Infect Dis Clin North Am. 2025 Sep;39(3):361-382. doi: 10.1016/j.idc.2025.02.009. Epub 2025 Apr 11. Optimizing Antibiotic Therapy in Musculoskeletal Infections. Cortés-Penfield NW(1), Justo JA(2), McCreary EK(3), Ryder JH(4). Author information: (1)Division of Infectious Diseases, University of Nebraska Medical Center, Omaha, NE, USA. Electronic address...

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PubMed Narrative Review Evidence Moderate

Infection in Orthopaedics.

Journal of orthopaedic trauma | 2015 | Cook GE, Markel DC, Ren W, Webb LX

[Indexed for MEDLINE] 6. Spine J. 2020 Mar;20(3):435-447. doi: 10.1016/j.spinee.2019.09.013. Epub 2019 Sep 23. Prophylactic postoperative measures to minimize surgical site infections in spine surgery: systematic review and evidence summary. Tan T(1), Lee H(1), Huang MS(2), Rutges J(3), Marion TE(4), Mathew J(5), Fitzgerald M(5), Gonzalvo A(6), Hunn MK(2), Kwon BK(7), Dvorak MF...

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PubMed Narrative Review Evidence Moderate

Protocol-Based Arthroplasty: Less Is More.

Orthopedics | 2015 | Gutowski CJ, Parvizi J, Purtill JJ

[Indexed for MEDLINE] 14. Spec Care Dentist. 2020 Mar;40(2):198-205. doi: 10.1111/scd.12450. Epub 2020 Jan 21. Prescribing practices for antibiotic prophylaxis in patients with prosthetic joints. Teixeira EC(1), Warren JJ(2), McKernan SC(2), McQuistan MR(3), Qian F(4). Author information: (1)Department of Operative Dentistry, The University of Iowa College of Dentistry, Iowa Ci...

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Crossref Journal Article Evidence Unclassified

Antibiotic prophylaxis practices in orthopedic surgery: Compliance with guidelines and clinical outcomes: A prospective observational study from a tertiary care hospital

International Journal of Orthopaedics Sciences | 2026 | Atul Patil, Rohit Dipwal

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PubMed Original Article Evidence Unclassified

Implementation of a Trauma Bay Checklist Improves Antibiotic Prophylaxis Compliance in Open Extremity Fractures.

The American surgeon | 2024 | Luke RD, Balio CP, Foley CK, Soult AP

[Indexed for MEDLINE] Conflict of interest statement: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. 18. Tierarztl Prax Ausg G Grosstiere Nutztiere. 2018 Apr;46(2):81-86. doi: 10.15653/TPG-170491. Epub 2018 May 4. Postoperative complications in equine ele...

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PubMed Original Article Evidence Unclassified

Type of antibiotic but not the duration of prophylaxis correlates with rates of fracture-related infection.

European journal of orthopaedic surgery & traumatology : orthopedie traumatologie | 2023 | Prebianchi S, Santos EC, Dell'Aquila A, Finelli C

[Indexed for MEDLINE] Conflict of interest statement: Each author certifies that neither he, nor any member of his immediate family, have funding or commercial associations (consultancies, stock ownership, equity interest, patent/licensing arrangements, etc.) that might pose a conflict of interest in connection with the submitted article.

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Crossref Journal Article Evidence Unclassified

What is the current evidence for antibiotic prophylaxis in orthopaedic surgery?

Orthopaedics and Trauma | 2023 | Benjamin Holmes, Ghiath Ismayl, Sohail Nisar

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Crossref Journal Article Evidence Unclassified

NCPD Tests

Orthopaedic Nursing | 2023

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Crossref Journal Article Evidence Unclassified

Are self-reported anthropometric data reliable enough to meet antibiotic prophylaxis guidelines in orthopedic surgery?

Orthopaedics & Traumatology: Surgery & Research | 2023 | Michael Butnaru, Matthieu Lalevée, Pierre-Alban Bouché, Thomas Aubert

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PubMed Original Article Evidence Unclassified

Pathogens and Shift of Resistance in Early Infections after Operative Fracture Fixation.

Surgical infections | 2022 | Oberhuber-Kurth LM, Angeli R, Lippmann N, Notov D

[Indexed for MEDLINE] 10. J Pediatr Orthop. 2018 May/Jun;38(5):287-292. doi: 10.1097/BPO.0000000000000812. Compliance With a Comprehensive Antibiotic Protocol Improves Infection Incidence in Pediatric Spine Surgery. Vandenberg C(1), Niswander C(2), Carry P(2), Bloch N(2), Pan Z(2), Erickson M(1), Garg S(1). Author information: (1)Orthopaedics Institute. (2)Musculoskeletal Resea...

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PubMed Original Article Evidence Unclassified

Antibiotic Prophylaxis for Prosthetic Joint Patients Undergoing Invasive Dental Procedures: Time for a Rethink?

The Journal of arthroplasty | 2022 | Springer BD, Baddour LM, Lockhart PB, Thornhill MH

[Indexed for MEDLINE] 16. Eur J Orthop Surg Traumatol. 2015 Feb;25(2):217-20. doi: 10.1007/s00590-014-1474-4. Epub 2014 May 9. Antibiotic prophylaxis during dental procedures in patients with in situ lower limb prosthetic joints. Alao U(1), Pydisetty R, Sandiford NA. Author information: (1)Department of Trauma and Orthopaedics, Whiston Hospital, Warrington Road. Prescot, Mersey...

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Crossref Journal Article Evidence Unclassified

Antibiotic prophylaxis in orthopedic surgery; has the time to reconsider the current practice arrived?

Journal of Orthopaedics | 2022 | Elisha Krasin, Yaniv Warschawski, Samuel Morgan, Michal Dekel

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PubMed Original Article Evidence Unclassified

Prolonged antibiotic prophylaxis use in elective orthopaedic surgery - a cross-sectional analysis.

BMC musculoskeletal disorders | 2021 | Rohrer F, Maurer A, Noetzli H, Gahl B

[Indexed for MEDLINE] Conflict of interest statement: The authors have no conflicts of interest to declare that are relevant to the content of this article. 12. Injury. 2020 Sep;51(9):1999-2003. doi: 10.1016/j.injury.2020.04.031. Epub 2020 May 12. Delay of Antibiotic Administration Greater than 2 Hours Predicts Surgical Site Infection in Open Fractures. Roddy E(1), Patterson JT...

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PubMed Original Article Evidence Unclassified

Does preoperative antibiotic prophylaxis affect sonication-based diagnosis in implant-associated infection?

Journal of orthopaedic research : official publication of the Orthopaedic Research Society | 2021 | Stephan A, Thürmer A, Glauche I, Nowotny J

[Indexed for MEDLINE] 20. Eur J Orthop Surg Traumatol. 2023 May;33(4):987-992. doi: 10.1007/s00590-022-03246-7. Epub 2022 Mar 9. Type of antibiotic but not the duration of prophylaxis correlates with rates of fracture-related infection. Prebianchi S(1), Santos EC(2), Dell'Aquila A(3), Finelli C(2), Reis FB(2), Salles MJ(3). Author information: (1)Department of Orthopedic and Tr...

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Crossref Journal Article Evidence Unclassified

Current Surgical Antibiotic Prophylaxis Practices: A Survey of Orthopaedic Surgeons in India

Indian Journal of Orthopaedics | 2021 | John Ashutosh Santoshi, Prateek Behera, Manoj Nagar, Ramesh Sen

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PubMed Original Article Evidence Unclassified

Delay of Antibiotic Administration Greater than 2 Hours Predicts Surgical Site Infection in Open Fractures.

Injury | 2020 | Roddy E, Patterson JT, Kandemir U

[Indexed for MEDLINE] Conflict of interest statement: Declaration of Competing Interest None. 13. Orthopedics. 2015 Oct;38(10):631-8. doi: 10.3928/01477447-20151002-06. Protocol-Based Arthroplasty: Less Is More. Gutowski CJ, Parvizi J, Purtill JJ. As a result of reading this article, physicians should be able to: 1. State an argument for, and background information on, patient-...

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PubMed Original Article Evidence Unclassified

Prescribing practices for antibiotic prophylaxis in patients with prosthetic joints.

Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry | 2020 | Teixeira EC, Warren JJ, McKernan SC, McQuistan MR

[Indexed for MEDLINE] 15. J Arthroplasty. 2022 Jul;37(7):1223-1226. doi: 10.1016/j.arth.2022.02.014. Epub 2022 Feb 11. Antibiotic Prophylaxis for Prosthetic Joint Patients Undergoing Invasive Dental Procedures: Time for a Rethink? Springer BD(1), Baddour LM(2), Lockhart PB(3), Thornhill MH(4). Author information: (1)OrthoCarolina Hip and Knee Center and Atrium Musculoskeletal I...

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PubMed Original Article Evidence Unclassified

Compliance With a Comprehensive Antibiotic Protocol Improves Infection Incidence in Pediatric Spine Surgery.

Journal of pediatric orthopedics | 2018 | Vandenberg C, Niswander C, Carry P, Bloch N

[Indexed for MEDLINE] Conflict of interest statement: Conflicts of Interest: Sumeet Garg has been paid a one-time consultant fee by Medtronic for teaching a course for surgeons in October 2014, a one-time consultant fee by DePuy Synthes Spine for teaching a course for surgeons in November 2013, payment for testifying in trial for a patient, and receives royalties from Decision...

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PubMed Original Article Evidence Unclassified

Postoperative complications in equine elective, clean orthopaedic surgery with/without antibiotic prophylaxis.

Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere | 2018 | Stöckle SD, Failing K, Koene M, Fey K

[Indexed for MEDLINE] Conflict of interest statement: The authors confirm that they do not have any conflict of interest. 19. J Orthop Res. 2021 Dec;39(12):2646-2652. doi: 10.1002/jor.25015. Epub 2021 Mar 8. Does preoperative antibiotic prophylaxis affect sonication-based diagnosis in implant-associated infection? Stephan A(1), Thürmer A(1), Glauche I(2), Nowotny J(1), Zwingenb...

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PubMed Original Article Evidence Unclassified

Antibiotic prophylaxis during dental procedures in patients with in situ lower limb prosthetic joints.

European journal of orthopaedic surgery & traumatology : orthopedie traumatologie | 2015 | Alao U, Pydisetty R, Sandiford NA

[Indexed for MEDLINE] 17. Am Surg. 2024 Sep;90(9):2273-2278. doi: 10.1177/00031348241244648. Epub 2024 Apr 8. Implementation of a Trauma Bay Checklist Improves Antibiotic Prophylaxis Compliance in Open Extremity Fractures. Luke RD(1), Balio CP(2), Foley CK(3), Soult AP(1). Author information: (1)Department of Surgery, Eastern Virginia Medical School, Norfolk, VA, USA. (2)Center...

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Crossref Journal Article Evidence Unclassified

Prosthetic joint infection, dental treatment and antibiotic prophylaxis

Orthopedic Review | 2009

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Crossref Journal Article Evidence Unclassified

Antibiotic prophylaxis in veterinary orthopaedic surgery

Veterinary and Comparative Orthopaedics and Traumatology | 2001 | S. C. Budsberg, J. A. Kirsch

Antibiotic prophylaxis is widespread in veterinary and human surgery. Key principles must be followed in case selection, drug choice and administration to ensure maximal effectiveness. More prospective clinical trials in veterinary orthopaedics are needed to better define which patients and which procedures will benefit from antimicrobial prophylaxis.

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Crossref Journal Article Evidence Unclassified

Prophylaxis against infection in orthopaedic practice

Current Orthopaedics | 1994 | W.J. Gillesple

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Crossref Journal Article Evidence Unclassified

Antibiotic Prophylaxis in Orthopedic Surgery

Clinical Infectious Diseases | 1991 | Carl W. Norden

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Crossref Journal Article Evidence Unclassified

Topical Antibiotic Irrigation in the Prophylaxis of Operative Wound Infections in Orthopedic Surgery

Orthopedic Clinics of North America | 1991 | Douglas R. Dirschl, Frank C. Wilson

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Crossref Journal Article Evidence Unclassified

Antibiotic Prophylaxis in Orthopedic Surgery

Clinical Orthopaedics and Related Research | 1976 | CARL W. NORDEN

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Crossref Review Article Evidence Moderate

Effectiveness of antibiotic prophylaxis prescribing for orthopedic surgery : a systematic review

Journal unavailable | Qian Chen

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Crossref Scholarly Work Evidence Unclassified

Antimicrobial Prophylaxis in Orthopaedic Surgery

Infection and Local Treatment in Orthopedic Surgery | A. Soriano, S. García-Ramiro, J. Mensa

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