Cartilage defects cause pain, swelling, mechanical symptoms; poor intrinsic healing. ACI: two-stage procedure — harvest cartilage → culture chondrocytes → reimplant under periosteal flap/biomatrix. Indications: symptomatic focal cartilage defects >2 cm² in young active patients. Alternatives: microfracture, OATS, osteochondral allograft. Complications: graft hypertrophy, delamination, failure.
What is the primary indication for Autologous Chondrocyte Implantation (ACI)?
What is the main advantage of third-generation ACI (MACI) over first-generation ACI?
Which of the following is a contraindication for ACI?
During the first stage of ACI, where is the cartilage harvested from?
What is the ideal defect size for ACI?
Which complication is commonly associated with first-generation ACI?
What is the main purpose of the collagen membrane in second-generation ACI?
What is the primary mechanism of action for ACI?
Which of the following is a common alternative to ACI for treating cartilage defects?
What is the key postoperative consideration following ACI?
