Orthonotes
Orthonotes
by the.bonestories
v3.0 Fusion
v3.0 Fusion
arthroplasty topic hub

Periprosthetic Joint Infection — Principles

Diagnosis uses consensus criteria (MSIS/ICM) combining major and minor criteria. Classify by timing: early (24 mo) — guides biofilm maturity and strategy. Treatment options: DAIR (debridement, antibiotics, implant retention), one‑stage or two‑stage revision; chronic suppression in poor hosts. Principles: radical debridement, exchange modular parts, biofilm‑active antibiotics (e.g., rifampicin combinations for staph). Prevention bundle: laminar flow, antibiotic prophylaxis, skin prep, glycemic control, normothermia.

Overview

Topic summary

View wiki
Diagnosis uses consensus criteria (MSIS/ICM) combining major and minor criteria. Classify by timing: early (<3 mo), delayed (3–24 mo), late (>24 mo) — guides biofilm maturity and strategy. Treatment options: DAIR (debridement, antibiotics, implant retention), one‑stage or two‑stage revision; chronic suppression in poor hosts. Principles: radical debridement, exchange modular parts, biofilm‑active antibiotics (e.g., rifampicin combinations for staph). Prevention bundle: laminar flow, antibiotic prophylaxis, skin prep, glycemic control, normothermia.
MCQs

High-yield practice questions

Start topic quiz
Question 1

Which of the following is a major criterion for diagnosing periprosthetic joint infection according to the Musculoskeletal Infection Society (MSIS) criteria?

Question 2

What is the recommended treatment strategy for an early periprosthetic joint infection (

Question 3

Which of the following antibiotics is particularly effective against biofilms associated with Staphylococcus species in periprosthetic joint infection?

Question 4

What is the classification of periprosthetic joint infections that occur more than 24 months after arthroplasty?

Question 5

Which of the following factors is NOT a recognized risk factor for periprosthetic joint infection?

Question 6

What is the primary benefit of optimizing glycemic control in patients undergoing joint arthroplasty?

Question 7

Which of the following is NOT part of the prevention bundle for periprosthetic joint infection?

Question 8

Which imaging modality is most useful for detecting implant loosening in suspected periprosthetic joint infection?

Question 9

In periprosthetic joint infection, the presence of which of the following in synovial fluid analysis is most indicative of infection?

Question 10

Which of the following is a common organism responsible for chronic periprosthetic joint infections?