Giant Cell Tumor — Campanacci Classification
Locally aggressive benign tumor in skeletally mature adults (20–40 yrs). Campanacci classification: Grade I (latent), II (active), III (aggressive with soft tissue extension). X-ray: eccentric lytic lesion, soap-bubble appearance. Treatment: extended curettage with adjuvants, PMMA, or wide excision. Denosumab indicated in sacral/spinal or unresectable lesions.
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