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Evidence Search

Search reputable indexed orthopaedic literature from multiple scholarly sources, classify the evidence, and link papers directly to wiki topics and cases.

Sources: PubMed, Europe PMC, Crossref

Linking results to Wiki: Tendon Healing and Rehabilitation
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Results are classified automatically from source metadata across PubMed, Europe PMC, and Crossref.
PubMed Crossref
PubMed Systematic Review / Meta-analysis Evidence High

Guidelines on offloading foot ulcers in persons with diabetes (IWGDF 2023 update).

Diabetes/metabolism research and reviews | 2024 | Bus SA, Armstrong DG, Crews RT, Gooday C

[Indexed for MEDLINE] 11. Adv Sci (Weinh). 2025 Sep;12(34):e09883. doi: 10.1002/advs.202509883. Epub 2025 Jun 19. Bioactive siRNA-Based Liposomes Promoted Tendon-Bone Healing in Osteoporotic Mice by Recovering the Stemness of CD248(+) TSPCs. Qian Y(1), Zhu J(2), He Y(3), Qin H(4), Qian P(1), Sun B(1), Huang H(1), Kuang C(1), Yang Q(1), Ou Y(5), Sun R(6), Xu F(1), Wang X(7), Luo...

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PubMed Randomized Controlled Trial Evidence High

Progressive early passive and active exercise therapy after surgical rotator cuff repair - study protocol for a randomized controlled trial (the CUT-N-MOVE trial).

Trials | 2018 | Kjær BH, Magnusson SP, Warming S, Henriksen M

[Indexed for MEDLINE] Conflict of interest statement: ETHICS APPROVAL AND CONSENT TO PARTICIPATE: The Health Research Study Board for the Capital Region Denmark approved the study on the 18 October 2016 (H-16033995). The study will be conducted in accordance with the local research ethics committee requirements and the principles of the Declaration of Helsinki, thus informed co...

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PubMed Narrative Review Evidence Moderate

Platelet-Rich Plasma (PRP): Molecular Mechanisms, Actions and Clinical Applications in Human Body.

International journal of molecular sciences | 2025 | Wu WS, Chen LR, Chen KH

[Indexed for MEDLINE] Conflict of interest statement: The authors declare no conflicts of interest. 16. Trials. 2018 Sep 3;19(1):470. doi: 10.1186/s13063-018-2839-5. Progressive early passive and active exercise therapy after surgical rotator cuff repair - study protocol for a randomized controlled trial (the CUT-N-MOVE trial). Kjær BH(1)(2), Magnusson SP(3)(4), Warming S(3), H...

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PubMed Narrative Review Evidence Moderate

Regenerative properties of bone marrow mesenchymal stem cell derived exosomes in rotator cuff tears.

Journal of translational medicine | 2025 | Chen J, Wang Z, Yi M, Yang Y

[Indexed for MEDLINE] Conflict of interest statement: Declarations. Ethics approval and consent to participate: This review does not require ethical review at this time. Consent for publication: All participants have given their consent for their data and personal information to be used for the publication of this study and all personal information involved has been anonymized...

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PubMed Narrative Review Evidence Moderate

A Review of the Role of Tendon Stem Cells in Tendon-Bone Regeneration.

Medical science monitor : international medical journal of experimental and clinical research | 2023 | Chen J, Jiang C, Yin L, Liu Y

[Indexed for MEDLINE] Conflict of interest statement: Conflict of interest: None declared 20. NeuroRehabilitation. 2005;20(1):35-42. Rehabilitation of burn injured patients following lightning and electrical trauma. Selvaggi G(1), Monstrey S, Van Landuyt K, Hamdi M, Blondeel P. Author information: (1)Department of Plastic Surgery, Burn Center, University Hospital, Gent, Belgium...

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PubMed Narrative Review Evidence Moderate

Extracorporeal Shockwave Therapy in the Management of Sports Medicine Injuries.

Current sports medicine reports | 2021 | Schroeder AN, Tenforde AS, Jelsing EJ

[Indexed for MEDLINE] 2. Phys Sportsmed. 2016;44(1):85-92. doi: 10.1080/00913847.2016.1108883. Epub 2015 Nov 7. Rotator cuff rehabilitation: current theories and practice. Osborne JD(1), Gowda AL(1), Wiater B(1), Wiater JM(1). Author information: (1)a Department of Orthopaedic Surgery , Beaumont Hospital , Royal Oak , MI , USA. A fully functioning, painless shoulder joint is es...

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PubMed Narrative Review Evidence Moderate

Physical therapy and precision rehabilitation in shoulder rotator cuff disease.

International orthopaedics | 2020 | Longo UG, Risi Ambrogioni L, Berton A, Candela V

[Indexed for MEDLINE] 4. Br J Sports Med. 2009 Apr;43(4):247-52. doi: 10.1136/bjsm.2008.054239. Epub 2009 Feb 24. Mechanotherapy: how physical therapists' prescription of exercise promotes tissue repair. Khan KM(1), Scott A. Author information: (1)Centre for Hip Health and Mobility and Department of Family Practice, University of British Columbia, Vancouver, Canada. karim.khan@...

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PubMed Narrative Review Evidence Moderate

Achilles tendinopathy.

Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons | 2020 | Maffulli N, Longo UG, Kadakia A, Spiezia F

[Indexed for MEDLINE] 6. Am Fam Physician. 2011 Jan 1;83(1):39-46. Stress fractures: diagnosis, treatment, and prevention. Patel DS(1), Roth M, Kapil N. Author information: (1)Rush-Copley Family Medicine Residency, Aurora, Illinois 60504, USA. Deepak_S_Patel@rsh.net Stress fractures are common injuries in athletes and military recruits. These injuries occur more commonly in low...

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PubMed Narrative Review Evidence Moderate

Flexor Tendon Injuries.

The Journal of the American Academy of Orthopaedic Surgeons | 2018 | Klifto CS, Capo JT, Sapienza A, Yang SS

[Indexed for MEDLINE] 18. J Transl Med. 2025 Jan 12;23(1):47. doi: 10.1186/s12967-024-06029-2. Regenerative properties of bone marrow mesenchymal stem cell derived exosomes in rotator cuff tears. Chen J(#)(1), Wang Z(#)(1), Yi M(#)(1), Yang Y(1), Tian M(1), Liu Y(2), Wang G(3), Shen H(4). Author information: (1)Department of Joint Surgery, The Affiliated Traditional Chinese Med...

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PubMed Narrative Review Evidence Moderate

Rotator cuff rehabilitation: current theories and practice.

The Physician and sportsmedicine | 2016 | Osborne JD, Gowda AL, Wiater B, Wiater JM

[Indexed for MEDLINE] 3. Int Orthop. 2020 May;44(5):893-903. doi: 10.1007/s00264-020-04511-2. Epub 2020 Mar 10. Physical therapy and precision rehabilitation in shoulder rotator cuff disease. Longo UG(1), Risi Ambrogioni L(2), Berton A(2), Candela V(2), Carnevale A(2)(3), Schena E(3), Gugliemelli E(4), Denaro V(2). Author information: (1)Department of Orthopaedic and Trauma Sur...

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PubMed Narrative Review Evidence Moderate

Distal Triceps Tendon Injuries.

Hand clinics | 2015 | Keener JD, Sethi PM

[Indexed for MEDLINE] 10. Diabetes Metab Res Rev. 2024 Mar;40(3):e3647. doi: 10.1002/dmrr.3647. Epub 2023 May 25. Guidelines on offloading foot ulcers in persons with diabetes (IWGDF 2023 update). Bus SA(1)(2), Armstrong DG(3), Crews RT(4), Gooday C(5), Jarl G(6)(7), Kirketerp-Moller K(8)(9), Viswanathan V(10), Lazzarini PA(11)(12). Author information: (1)Department of Rehabili...

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PubMed Narrative Review Evidence Moderate

ACL graft healing and biologics.

Clinics in sports medicine | 2013 | Muller B, Bowman KF Jr, Bedi A

[Indexed for MEDLINE] 13. J Hand Ther. 2012 Apr-Jun;25(2):123-31; quiz 132. doi: 10.1016/j.jht.2011.08.003. Epub 2011 Nov 1. Specialized connective tissue: bone, the structural framework of the upper extremity. Weatherholt AM(1), Fuchs RK, Warden SJ. Author information: (1)Center for Translational Musculoskeletal Research, School of Health and Rehabilitation Sciences, Indiana U...

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PubMed Narrative Review Evidence Moderate

Stress fractures: diagnosis, treatment, and prevention.

American family physician | 2011 | Patel DS, Roth M, Kapil N

[Indexed for MEDLINE] 7. Foot Ankle Spec. 2022 Jun;15(3):236-243. doi: 10.1177/1938640020950895. Epub 2020 Aug 25. Adverse Events Following Minimally Invasive Achilles Tendon Repair. Idarraga AJ(1), Bohl DD(1), Barnard E(2), Movassaghi K(3), Hamid KS(1), Schiff AP(4). Author information: (1)Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois. (2...

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PubMed Original Article Evidence Unclassified

Bioactive siRNA-Based Liposomes Promoted Tendon-Bone Healing in Osteoporotic Mice by Recovering the Stemness of CD248(+) TSPCs.

Advanced science (Weinheim, Baden-Wurttemberg, Germany) | 2025 | Qian Y, Zhu J, He Y, Qin H

[Indexed for MEDLINE] Conflict of interest statement: The authors declare no conflict of interest. 12. Clin Sports Med. 2013 Jan;32(1):93-109. doi: 10.1016/j.csm.2012.08.010. ACL graft healing and biologics. Muller B(1), Bowman KF Jr, Bedi A. Author information: (1)Department of Orthopaedic Surgery, UPMC Center for Sports Medicine, University of Pittsburgh, PA 15213, USA. Opera...

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PubMed Narrative Review Evidence Moderate

Mechanotherapy: how physical therapists' prescription of exercise promotes tissue repair.

British journal of sports medicine | 2009 | Khan KM, Scott A

[Indexed for MEDLINE] Conflict of interest statement: Competing interests: None. 5. Foot Ankle Surg. 2020 Apr;26(3):240-249. doi: 10.1016/j.fas.2019.03.009. Epub 2019 Apr 18. Achilles tendinopathy. Maffulli N(1), Longo UG(2), Kadakia A(3), Spiezia F(4). Author information: (1)Department of Musculoskeletal Disorders, University of Salerno School of Medicine, Surgery and Dentistr...

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PubMed Original Article Evidence Unclassified

A Mesoporous Silica-Loaded Multi-Functional Hydrogel Enhanced Tendon Healing via Immunomodulatory and Pro-Regenerative Effects.

Advanced healthcare materials | 2024 | Wan R, Luo Z, Nie X, Feng X

[Indexed for MEDLINE] 9. Hand Clin. 2015 Nov;31(4):641-50. doi: 10.1016/j.hcl.2015.06.010. Distal Triceps Tendon Injuries. Keener JD(1), Sethi PM(2). Author information: (1)Department of Orthopaedic Surgery, Washington University, CB# 8233, 660 South Euclid Avenue, St Louis, MO 63110, USA. Electronic address: keenerj@wustl.edu. (2)The ONS Sports and Shoulder Service, 6 Greenwic...

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PubMed Original Article Evidence Unclassified

Adverse Events Following Minimally Invasive Achilles Tendon Repair.

Foot & ankle specialist | 2022 | Idarraga AJ, Bohl DD, Barnard E, Movassaghi K

[Indexed for MEDLINE] 8. Adv Healthc Mater. 2024 Oct;13(26):e2400968. doi: 10.1002/adhm.202400968. Epub 2024 May 11. A Mesoporous Silica-Loaded Multi-Functional Hydrogel Enhanced Tendon Healing via Immunomodulatory and Pro-Regenerative Effects. Wan R(1), Luo Z(1), Nie X(2)(3), Feng X(1), He Y(1), Li F(4), Liu S(4), Chen W(1), Qi B(5), Qin H(6), Luo W(1), Zhang H(1), Jiang H(7),...

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Crossref Journal Article Evidence Unclassified

MRL/MpJ tendon matrix‐derived therapeutic promotes improved healing outcomes in scar‐mediated canonical tendon healing

Journal of Orthopaedic Research | 2021 | Juan Paredes, Ashley Pekmezian, Nelly Andarawis‐Puri

AbstractTendons are commonly injured connective soft tissues characterized by an ineffective healing response that results in scar formation and loss of functional and structural properties. Naturally occurring extracellular matrix (ECM) constructs have become a promising therapeutic for tendon injuries due to their capacity to harness a complex biological environment. However,...

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PubMed Original Article Evidence Unclassified

Genetics in orthopaedic practice.

Journal of biological regulators and homeostatic agents | 2019 | Aicale R, Tarantino D, Maccauro G, Peretti GM

[Indexed for MEDLINE] 15. Int J Mol Sci. 2025 Nov 6;26(21):10804. doi: 10.3390/ijms262110804. Platelet-Rich Plasma (PRP): Molecular Mechanisms, Actions and Clinical Applications in Human Body. Wu WS(1), Chen LR(2)(3), Chen KH(4)(5). Author information: (1)Department of Medical Education, Taipei Tzu-Chi Hospital, The Buddhist Tzu-Chi Medical Foundation, New Taipei City 231, Taiw...

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PubMed Original Article Evidence Unclassified

Specialized connective tissue: bone, the structural framework of the upper extremity.

Journal of hand therapy : official journal of the American Society of Hand Therapists | 2012 | Weatherholt AM, Fuchs RK, Warden SJ

[Indexed for MEDLINE] 14. J Biol Regul Homeost Agents. 2019 Mar-Apr;33(2 Suppl. 1):103-117. XIX Congresso Nazionale S.I.C.O.O.P. Societa' Italiana Chirurghi Ortopedici Dell'ospedalita' Privata Accreditata. Genetics in orthopaedic practice. Aicale R(1)(2), Tarantino D(1), Maccauro G(3)(4), Peretti GM(5)(6), Maffulli N(1)(2)(7). Author information: (1)Department of Musculoskeleta...

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