Evidence Search

G-protein-coupled estrogen receptor-1 facilitates chondrocyte proliferation in pubertal epiphyseal growth plate via PTHrP/Ihh regulation.

Bone & joint research | 2025 | Chou YS, Lin SY, Chuang SC, Shih PY

Conflict of interest statement: The authors report support for attending meetings and/or travel from the Regenerative Medicine and Cell Therapy Research Center, Kaohsiung Medical University (KMU-TC112A02), unrelated to this study. 5. Front Endocrinol (Lausanne). 2012 Jan 9;2:113. doi: 10.3389/fendo.2011.00113. eCollection 2011. Genetic regulation of the growth plate. Karimian E...

Primary cilia in growth plates orchestrate long bone development.

Fundamental research | 2025 | Zhang L, Xu X, Tao D, Li X

Conflict of interest statement: The authors declare that they have no conflicts of interest in this work. 17. Pediatr Res. 2009 Dec;66(6):654-9. doi: 10.1203/PDR.0b013e3181beaa8c. Epiphyseal fusion in the human growth plate does not involve classical apoptosis. Emons J(1), Chagin AS, Hultenby K, Zhivotovsky B, Wit JM, Karperien M, Sävendahl L. Author information: (1)Department...

Piezo1 expression in chondrocytes controls endochondral ossification and osteoarthritis development.

Bone research | 2024 | Brylka LJ, Alimy AR, Tschaffon-Müller MEA, Jiang S

[Indexed for MEDLINE] Conflict of interest statement: The authors declare no competing interests. 2. Matrix Biol. 2024 Nov;133:86-102. doi: 10.1016/j.matbio.2024.08.002. Epub 2024 Aug 17. Fibronectin isoforms promote postnatal skeletal development. Dinesh NEH(1), Baratang N(2), Rosseau J(2), Mohapatra R(1), Li L(1), Mahalingam R(3), Tiedemann K(4), Campeau PM(2), Reinhardt DP(5...

Fibronectin isoforms promote postnatal skeletal development.

Matrix biology : journal of the International Society for Matrix Biology | 2024 | Dinesh NEH, Baratang N, Rosseau J, Mohapatra R

[Indexed for MEDLINE] Conflict of interest statement: Declaration of competing interest The authors declare no competing interests. 3. Methods Mol Biol. 2021;2245:105-119. doi: 10.1007/978-1-0716-1119-7_8. Laser Capture Microdissection of Mouse Growth Plate Cartilage. Kikani B(1), Lui JC(2). Author information: (1)Section on Growth and Development, Eunice Kennedy Shriver Nation...

α-parvin controls chondrocyte column formation and regulates long bone development.

Bone research | 2023 | Yuan J, Guo L, Wang J, Zhou Z

[Indexed for MEDLINE] Conflict of interest statement: The authors declare no competing interests. 12. PLoS One. 2017 May 3;12(5):e0176752. doi: 10.1371/journal.pone.0176752. eCollection 2017. Spatial regulation of bone morphogenetic proteins (BMPs) in postnatal articular and growth plate cartilage. Garrison P(1), Yue S(1), Hanson J(2), Baron J(1), Lui JC(1). Author information:...

Cross-talk between EGFR and BMP signals regulates chondrocyte maturation during endochondral ossification.

Developmental dynamics : an official publication of the American Association of Anatomists | 2022 | Lees-Shepard JB, Flint K, Fisher M, Omi M

[Indexed for MEDLINE] 11. Bone Res. 2023 Aug 22;11(1):46. doi: 10.1038/s41413-023-00284-7. α-parvin controls chondrocyte column formation and regulates long bone development. Yuan J(1)(2), Guo L(3), Wang J(3), Zhou Z(4), Wu C(5)(6). Author information: (1)Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Shenzhen Key Laboratory of Cell Microenvi...

Brd4 is required for chondrocyte differentiation and endochondral ossification.

Bone | 2022 | Paradise CR, Galvan ML, Pichurin O, Jerez S

[Indexed for MEDLINE] 15. Histochem Cell Biol. 2016 Jan;145(1):67-79. doi: 10.1007/s00418-015-1365-8. Epub 2015 Oct 14. Expression of Sulf1 and Sulf2 in cartilage, bone and endochondral fracture healing. Zaman G(1), Staines KA(2), Farquharson C(2), Newton PT(2), Dudhia J(3), Chenu C(1), Pitsillides AA(1), Dhoot GK(4). Author information: (1)Department of Comparative Biomedical...

Laser Capture Microdissection of Mouse Growth Plate Cartilage.

Methods in molecular biology (Clifton, N.J.) | 2021 | Kikani B, Lui JC

[Indexed for MEDLINE] 4. Bone Joint Res. 2025 Jul 1;14(7):589-600. doi: 10.1302/2046-3758.147.BJR-2024-0347.R1. G-protein-coupled estrogen receptor-1 facilitates chondrocyte proliferation in pubertal epiphyseal growth plate via PTHrP/Ihh regulation. Chou YS(1)(2), Lin SY(1)(2)(3)(4)(5), Chuang SC(1)(2), Shih PY(1)(2), Chen CH(1)(2)(3)(6)(7)(8)(9), Ho ML(1)(2)(10), Chang JK(1)(2...

Cartilage -specific knockout of Sirt1 significantly reduces bone quality and catch-up growth efficiency.

Bone | 2020 | Shtaif B, Bar-Maisels M, Gabet Y, Hiram-Bab S

[Indexed for MEDLINE] Conflict of interest statement: Declaration of competing interest The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported. 14. Bone. 2022 Jan;154:116234. doi: 10.1016/j.bone.2021.116234. Epub 2021 Oct 23. Brd4 is required for chondrocyte differentiation and endochondral ossi...

C-type natriuretic peptide improves growth retardation in a mouse model of cardio-facio-cutaneous syndrome.

Human molecular genetics | 2019 | Inoue SI, Morozumi N, Yoshikiyo K, Maeda H

[Indexed for MEDLINE]

ADAMTS10-mediated tissue disruption in Weill-Marchesani syndrome.

Human molecular genetics | 2018 | Mularczyk EJ, Singh M, Godwin ARF, Galli F

[Indexed for MEDLINE] 9. Environ Toxicol Pharmacol. 2016 Oct;47:92-99. doi: 10.1016/j.etap.2016.09.002. Epub 2016 Sep 4. The effects of chlormequat chloride on the development of pubertal male rats. Huang D(1), Wu S(1), Pan Y(1), Meng Q(1), Chu H(1), Jiang J(1), Shang L(1), Hao W(2). Author information: (1)Department of Toxicology, School of Public Health, Peking University, Be...

Proposal of patient-specific growth plate cartilage xenograft model for FGFR3 chondrodysplasia.

Osteoarthritis and cartilage | 2018 | Kimura T, Ozaki T, Fujita K, Yamashita A

[Indexed for MEDLINE] 20. Hum Mol Genet. 2019 Jan 1;28(1):74-83. doi: 10.1093/hmg/ddy333. C-type natriuretic peptide improves growth retardation in a mouse model of cardio-facio-cutaneous syndrome. Inoue SI(1), Morozumi N(2), Yoshikiyo K(2), Maeda H(2)(3), Aoki Y(1). Author information: (1)Department of Medical Genetics, Tohoku University School of Medicine, Sendai. (2)Immunolo...

Spatial regulation of bone morphogenetic proteins (BMPs) in postnatal articular and growth plate cartilage.

PloS one | 2017 | Garrison P, Yue S, Hanson J, Baron J

[Indexed for MEDLINE] Conflict of interest statement: Competing Interests: The authors have declared that no competing interests exist. 13. Bone. 2020 Sep;138:115468. doi: 10.1016/j.bone.2020.115468. Epub 2020 Jun 5. Cartilage -specific knockout of Sirt1 significantly reduces bone quality and catch-up growth efficiency. Shtaif B(1), Bar-Maisels M(2), Gabet Y(3), Hiram-Bab S(4),...

The effects of chlormequat chloride on the development of pubertal male rats.

Environmental toxicology and pharmacology | 2016 | Huang D, Wu S, Pan Y, Meng Q

[Indexed for MEDLINE] 10. Dev Dyn. 2022 Jan;251(1):75-94. doi: 10.1002/dvdy.438. Epub 2021 Nov 27. Cross-talk between EGFR and BMP signals regulates chondrocyte maturation during endochondral ossification. Lees-Shepard JB(1), Flint K(2), Fisher M(2), Omi M(1), Richard K(1), Antony M(2), Chen PJ(2), Yadav S(2), Threadgill D(3)(4), Maihle NJ(5)(6), Dealy CN(2)(7)(8)(9). Author in...

Expression of Sulf1 and Sulf2 in cartilage, bone and endochondral fracture healing.

Histochemistry and cell biology | 2016 | Zaman G, Staines KA, Farquharson C, Newton PT

[Indexed for MEDLINE] 16. Fundam Res. 2025 May 3;5(5):2368-2381. doi: 10.1016/j.fmre.2025.04.014. eCollection 2025 Sep. Primary cilia in growth plates orchestrate long bone development. Zhang L(1), Xu X(1), Tao D(1), Li X(1), Niu P(1), Gong X(1), Li G(2), Yu M(3), Sun Y(1). Author information: (1)Shanghai Engineering Research Center of Tooth Restoration and Regeneration & Tongj...

Epiphyseal Growth Plate Fracture-Separations

Pediatric Orthopedic Deformities, Volume 1 | 2016 | Frederic Shapiro

Hox11 genes regulate postnatal longitudinal bone growth and growth plate proliferation.

Biology open | 2015 | Pineault KM, Swinehart IT, Garthus KN, Ho E

Conflict of interest statement: Competing interests The authors declare no competing or financial interests. 8. Hum Mol Genet. 2018 Nov 1;27(21):3675-3687. doi: 10.1093/hmg/ddy276. ADAMTS10-mediated tissue disruption in Weill-Marchesani syndrome. Mularczyk EJ(1)(2), Singh M(1)(2), Godwin ARF(1)(2), Galli F(2), Humphreys N(3), Adamson AD(3), Mironov A(3), Cain SA(1)(2), Sengle G...

SHP2 regulates chondrocyte terminal differentiation, growth plate architecture and skeletal cell fates.

PLoS genetics | 2014 | Bowen ME, Ayturk UM, Kurek KC, Yang W

[Indexed for MEDLINE] Conflict of interest statement: The authors have declared that no competing interests exist. 19. Osteoarthritis Cartilage. 2018 Nov;26(11):1551-1561. doi: 10.1016/j.joca.2018.07.015. Epub 2018 Aug 4. Proposal of patient-specific growth plate cartilage xenograft model for FGFR3 chondrodysplasia. Kimura T(1), Ozaki T(2), Fujita K(2), Yamashita A(2), Morioka...

Genetic regulation of the growth plate.

Frontiers in endocrinology | 2011 | Karimian E, Chagin AS, Sävendahl L

6. Am J Orthop (Belle Mead NJ). 2015 Feb;44(2):61-7. Factors affecting bone growth. Gkiatas I(1), Lykissas M, Kostas-Agnantis I, Korompilias A, Batistatou A, Beris A. Author information: (1)University of Ioannina, School of Medicine, Division of Orthopaedic Surgery, Ioannina, Greece. john.gkiatas@gmail.com. Bone growth and development are products of the complex interactions of...

Epiphyseal fusion in the human growth plate does not involve classical apoptosis.

Pediatric research | 2009 | Emons J, Chagin AS, Hultenby K, Zhivotovsky B

[Indexed for MEDLINE] 18. PLoS Genet. 2014 May 29;10(5):e1004364. doi: 10.1371/journal.pgen.1004364. eCollection 2014. SHP2 regulates chondrocyte terminal differentiation, growth plate architecture and skeletal cell fates. Bowen ME(1), Ayturk UM(1), Kurek KC(1), Yang W(2), Warman ML(1). Author information: (1)Orthopaedic Research Laboratories, Boston Children's Hospital, Boston...

Epiphyseal Growth Plate Fractures

Journal unavailable | 2007

Epiphyseal Growth Plate Fracture–Separations

Pediatric Orthopedic Deformities | 2001 | FREDERIC SHAPIRO

Anatomy and Growth

Epiphyseal Growth Plate Fractures

Evaluation

Epiphyseal Growth Plate Fractures

Classification

Epiphyseal Growth Plate Fractures

Complications

Epiphyseal Growth Plate Fractures

Metatarsals

Epiphyseal Growth Plate Fractures

Epidemiology

Epiphyseal Growth Plate Fractures

Metacarpal

Epiphyseal Growth Plate Fractures

Management

Epiphyseal Growth Plate Fractures

Ribs

Epiphyseal Growth Plate Fractures

Proximal Radius

Epiphyseal Growth Plate Fractures

Prognosis

Epiphyseal Growth Plate Fractures

Etiology

Epiphyseal Growth Plate Fractures