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Evidence Search

Search reputable indexed orthopaedic literature from multiple scholarly sources, classify the evidence, and link papers directly to wiki topics and cases.

Sources: PubMed, Europe PMC, Crossref

Linking results to Wiki: Ewing’s Sarcoma — Protocols
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Results are classified automatically from source metadata across PubMed, Europe PMC, and Crossref.
PubMed Crossref
PubMed Guideline / Consensus Evidence High

Consensus recommendations for systemic therapies in the management of relapsed Ewing sarcoma: A report from the National Ewing Sarcoma Tumor Board.

Cancer | 2024 | Gupta A, Dietz MS, Riedel RF, Dhir A

[Indexed for MEDLINE] 11. Lancet. 2022 Oct 29;400(10362):1513-1521. doi: 10.1016/S0140-6736(22)01790-1. Comparison of two chemotherapy regimens in patients with newly diagnosed Ewing sarcoma (EE2012): an open-label, randomised, phase 3 trial. Brennan B(1), Kirton L(2), Marec-Bérard P(3), Gaspar N(4), Laurence V(5), Martín-Broto J(6), Sastre A(7), Gelderblom H(8), Owens C(9), Fe...

PubMed Guideline / Consensus Evidence High

Consensus recommendations in the management of Ewing sarcoma from the National Ewing Sarcoma Tumor Board.

Cancer | 2023 | Gupta A, Riedel RF, Shah C, Borinstein SC

[Indexed for MEDLINE] 6. J Surg Oncol. 1993 Mar;52(3):188-92. doi: 10.1002/jso.2930520315. Ewing's sarcoma. Iyer RS(1), Rao SR, Gurjal A, Nair CN, Pai SK, Kurkure PA, Pande SC, Advani SH. Author information: (1)Department of Medical Oncology, Tata Memorial Hospital, Bombay, India. Between 1984-1987, 50 patients with Ewing's sarcoma of the bone were entered on combined modality...

PubMed Randomized Controlled Trial Evidence High

Comparison of two chemotherapy regimens in patients with newly diagnosed Ewing sarcoma (EE2012): an open-label, randomised, phase 3 trial.

Lancet (London, England) | 2022 | Brennan B, Kirton L, Marec-Bérard P, Gaspar N

[Indexed for MEDLINE] Conflict of interest statement: Declaration of interests SS has received honoraria and consulting fees from GSK, Lilly, and Ceridwen Oncology. JM-B reports institutional grants from Adaptimmune, Amgen, AROG, Bayer, Blueprint, Bristol Myers Squibb, Celgene, Daichii-Sankyo, Deciphera, Eisai, FORMA, GSK, IMMIX Biopharma, Karyopharm, Lilly, Nektar, Novartis, P...

PubMed Guideline / Consensus Evidence High

Treatment pathway of bone sarcoma in children, adolescents, and young adults.

Cancer | 2017 | Reed DR, Hayashi M, Wagner L, Binitie O

[Indexed for MEDLINE] 14. Ann Pathol. 2011 Dec;31(6):455-65. doi: 10.1016/j.annpat.2011.10.009. Epub 2011 Nov 29. [Place of the pathologist in the management of primary bone tumors (osteosarcoma and Ewing's family tumors after neoadjuvant treatment)]. [Article in French] Gomez-Brouchet A(1), Bouvier C, Decouvelaere AV, Larousserie F, Aubert S, Leroy X, Guinebretière JM, Coulomb...

PubMed Narrative Review Evidence Moderate

Small round cell sarcomas.

Nature reviews. Disease primers | 2022 | Cidre-Aranaz F, Watson S, Amatruda JF, Nakamura T

[Indexed for MEDLINE] 17. Strahlenther Onkol. 1993 Dec;169(12):695-708. [Therapy of Ewing's sarcoma]. [Article in German] Dunst J(1), Sauer R. Author information: (1)Strahlentherapeutische Klinik und Poliklinik, Universität Erlangen-Nürnberg. Therapy of Ewing's sarcoma requires a qualified clinical, radiological, and pathohistological diagnosis and, in particular, an optimal th...

PubMed Narrative Review Evidence Moderate

Management of sarcomas in children, adolescents and adults: Interactions in two different age groups under the umbrellas of GSF-GETO and SFCE, with the support of the NETSARC+ network.

Bulletin du cancer | 2021 | Bompas E, Martin V, Meniai F, Toulmonde M

[Indexed for MEDLINE] 20. Rev Recent Clin Trials. 2017;12(1):19-23. doi: 10.2174/1574887112666170120100147. A Review of Ewing Sarcoma Treatment: Is it Still a Subject of Debate? Kridis WB(1), Toumi N, Chaari H, Khanfir A, Ayadi K, Keskes H, Boudawara T, Daoud J, Frikha M. Author information: (1)Department of Oncology Habib Bourguiba Hospital, Sfax, Tunisia. BACKGROUND: The Ewin...

PubMed Narrative Review Evidence Moderate

Advances in immune checkpoint inhibitors for bone sarcoma therapy.

Journal of bone oncology | 2019 | Thanindratarn P, Dean DC, Nelson SD, Hornicek FJ

13. Cancer. 2017 Jun 15;123(12):2206-2218. doi: 10.1002/cncr.30589. Epub 2017 Mar 21. Treatment pathway of bone sarcoma in children, adolescents, and young adults. Reed DR(1)(2)(3), Hayashi M(4), Wagner L(5), Binitie O(1)(3)(6), Steppan DA(4), Brohl AS(1)(2), Shinohara ET(7), Bridge JA(8), Loeb DM(4), Borinstein SC(9), Isakoff MS(10). Author information: (1)Sarcoma Department,...

PubMed Narrative Review Evidence Moderate

Chemotherapy for bone sarcomas in adults: the MD anderson experience.

American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting | 2015 | Benjamin RS, Wagner MJ, Livingston JA, Ravi V

[Indexed for MEDLINE] 16. Nat Rev Dis Primers. 2022 Oct 6;8(1):66. doi: 10.1038/s41572-022-00393-3. Small round cell sarcomas. Cidre-Aranaz F(1)(2), Watson S(3)(4), Amatruda JF(5)(6), Nakamura T(7), Delattre O(4), de Alava E(8)(9), Dirksen U(10), Grünewald TGP(11)(12)(13). Author information: (1)Division of Translational Paediatric Sarcoma Research, German Cancer Research Cente...

PubMed Randomized Controlled Trial Evidence High

Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone.

The New England journal of medicine | 2003 | Grier HE, Krailo MD, Tarbell NJ, Link MP

[Indexed for MEDLINE] 9. Cancer. 1999 Feb 1;85(3):725-31. Extraskeletal Ewing's sarcoma. Ahmad R(1), Mayol BR, Davis M, Rougraff BT. Author information: (1)Department of Orthopaedics, Indiana University School of Medicine, Indianapolis 46202, USA. BACKGROUND: Ewing's sarcoma usually is identified as a primary malignancy of bone affecting children and young adults. Extraskeletal...

PubMed Narrative Review Evidence Moderate

[Place of the pathologist in the management of primary bone tumors (osteosarcoma and Ewing's family tumors after neoadjuvant treatment)].

Annales de pathologie | 2011 | Gomez-Brouchet A, Bouvier C, Decouvelaere AV, Larousserie F

[Indexed for MEDLINE] 15. Am Soc Clin Oncol Educ Book. 2015:e656-60. doi: 10.14694/EdBook_AM.2015.35.e656. Chemotherapy for bone sarcomas in adults: the MD anderson experience. Benjamin RS(1), Wagner MJ(1), Livingston JA(1), Ravi V(1), Patel SR(1). Author information: (1)From the Department of Sarcoma Medical Oncology, Division of Cancer Medicine, The University of Texas MD And...

PubMed Narrative Review Evidence Moderate

Ewing's sarcoma.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists | 2010 | Karosas AO

[Indexed for MEDLINE] 3. Methods Mol Biol. 2022;2373:283-296. doi: 10.1007/978-1-0716-1693-2_17. 3D Biofabricated In Vitro Models of Vascularized and Mineralized Bone Tissues. Colombo MV(1)(2), Bersini S(1), Arrigoni C(1), Moretti M(3)(4)(5). Author information: (1)Regenerative Medicine Technologies Laboratory, Ente Ospedaliero Cantonale, Lugano, Switzerland. (2)Department of C...

PubMed Original Article Evidence Unclassified

Shared decision making in primary malignant bone tumour surgery around the knee in children and young adults: protocol for a prospective study.

Journal of orthopaedic surgery and research | 2024 | Blom KJ, Bekkering WP, Fiocco M, van de Sande MA

[Indexed for MEDLINE] Conflict of interest statement: The authors declare no competing interests. 19. Bull Cancer. 2021 Feb;108(2):163-176. doi: 10.1016/j.bulcan.2020.10.009. Epub 2021 Jan 14. Management of sarcomas in children, adolescents and adults: Interactions in two different age groups under the umbrellas of GSF-GETO and SFCE, with the support of the NETSARC+ network. Bo...

PubMed Original Article Evidence Unclassified

Modeling Ewing Sarcoma Lung Metastasis.

Current protocols | 2023 | Dasgupta A, Kurenbekova L, Patel TD, Rajapakshe K

[Indexed for MEDLINE] Conflict of interest statement: CONFLICT OF INTEREST STATEMENT: No conflict of interest to declare. 5. Cancer. 2023 Nov 1;129(21):3363-3371. doi: 10.1002/cncr.34942. Epub 2023 Jul 5. Consensus recommendations in the management of Ewing sarcoma from the National Ewing Sarcoma Tumor Board. Gupta A(1), Riedel RF(2), Shah C(3), Borinstein SC(4), Isakoff MS(5),...

PubMed Original Article Evidence Unclassified

3D Biofabricated In Vitro Models of Vascularized and Mineralized Bone Tissues.

Methods in molecular biology (Clifton, N.J.) | 2022 | Colombo MV, Bersini S, Arrigoni C, Moretti M

[Indexed for MEDLINE] 4. Curr Protoc. 2023 Feb;3(2):e670. doi: 10.1002/cpz1.670. Modeling Ewing Sarcoma Lung Metastasis. Dasgupta A(1), Kurenbekova L(1), Patel TD(1), Rajapakshe K(2), Ghosal G(3), Nirala B(1), Coarfa C(4)(5), Yustein J(1). Author information: (1)Texas Children's Cancer and Hematology Centers and The Faris D. Virani Ewing Sarcoma Center, Baylor College of Medici...

Crossref Journal Article Evidence Unclassified

Experience-Based Opioid-Sparing Orthopedic Surgical Protocols

Journal of Orthopaedic Experience & Innovation | 2021 | Cassie Chin, Scott Sigman

Specific protocols have been established for each of the time windows involved in the perioperative surgical experience. We use a combination of medications, medical devices, local and regional anesthetics to minimize pain while trying to avoid Opioids.

PubMed Case Report / Series Evidence Low

Primary intradural extraosseous Ewing sarcoma of the spine: case report and literature review.

Neurosurgery | 2011 | Karikari IO, Mehta AI, Nimjee S, Hodges TR

[Indexed for MEDLINE] 8. N Engl J Med. 2003 Feb 20;348(8):694-701. doi: 10.1056/NEJMoa020890. Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone. Grier HE(1), Krailo MD, Tarbell NJ, Link MP, Fryer CJ, Pritchard DJ, Gebhardt MC, Dickman PS, Perlman EJ, Meyers PA, Donaldson SS, Moore S, Rausen AR, Vietti T...

PubMed Narrative Review Evidence Moderate

[Therapy of Ewing's sarcoma].

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] | 1993 | Dunst J, Sauer R

[Indexed for MEDLINE] 18. J Orthop Surg Res. 2024 Nov 2;19(1):714. doi: 10.1186/s13018-024-05192-y. Shared decision making in primary malignant bone tumour surgery around the knee in children and young adults: protocol for a prospective study. Blom KJ(1)(2), Bekkering WP(2), Fiocco M(2)(3)(4), van de Sande MA(2)(5), Schreuder HW(2)(6), van der Heijden L(2), Jutte PC(7), Haveman...

PubMed Original Article Evidence Unclassified

[Ewing's sarcoma].

Gan to kagaku ryoho. Cancer & chemotherapy | 2004 | Goto T, Hozumi T, Kondo T

[Indexed for MEDLINE] 2. Am J Health Syst Pharm. 2010 Oct 1;67(19):1599-605. doi: 10.2146/ajhp090526. Ewing's sarcoma. Karosas AO(1). Author information: (1)Geisinger Medical Center, Danville, PA 17822, USA. akarosas@geisinger.edu PURPOSE: The current treatments of and new therapeutic options for the management of Ewing's sarcoma (ES) are reviewed. SUMMARY: ES is the second mos...

PubMed Original Article Evidence Unclassified

Extraskeletal Ewing's sarcoma.

Cancer | 1999 | Ahmad R, Mayol BR, Davis M, Rougraff BT

[Indexed for MEDLINE] 10. Cancer. 2024 Dec 1;130(23):4028-4039. doi: 10.1002/cncr.35537. Epub 2024 Aug 25. Consensus recommendations for systemic therapies in the management of relapsed Ewing sarcoma: A report from the National Ewing Sarcoma Tumor Board. Gupta A(1)(2), Dietz MS(3), Riedel RF(4), Dhir A(5), Borinstein SC(6), Isakoff MS(7), Aye JM(8), Rainusso N(9), Armstrong AE(...

PubMed Original Article Evidence Unclassified

Ewing's sarcoma.

Journal of surgical oncology | 1993 | Iyer RS, Rao SR, Gurjal A, Nair CN

[Indexed for MEDLINE] 7. Neurosurgery. 2011 Oct;69(4):E995-9. doi: 10.1227/NEU.0b013e318223b7c7. Primary intradural extraosseous Ewing sarcoma of the spine: case report and literature review. Karikari IO(1), Mehta AI, Nimjee S, Hodges TR, Tibaleka J, Montgomery C, Simpson L, Cummings TJ, Bagley CA. Author information: (1)Department of Surgery, Duke University Medical Center, Du...