Evidence Search

A Case Report of Metallosis-Related Aseptic Loosening of Primary Total Knee Arthroplasty Implant Managed with Revision Total Knee Arthroplasty

A Case Report of Metallosis-Related Aseptic Loosening of Primary Total Knee Arthroplasty Implant Managed with Revision Total Knee Arthroplasty | 2026 | Debasish Sarkar

Metallosis is a rare but serious long-term complication following total knee arthroplasty (TKA), most commonly resulting from polyethylene insert wear that leads to unintended metal-on-metal articulation and subsequent metallic debris deposition. We present the case of a 70-year-old female who developed progressive pain, stiffness, and instability in her right knee, 19 years af...

BIOMARKERS IN FOCUS: ADDRESSING WEAR AND ASEPTIC LOOSENING IN PATIENTS WITH TOTAL HIP ARTHROPLASTY

Orthopaedic Proceedings | 2025 | Gema Valles

Total hip replacement (THR) is a highly successful and impactful procedure for end-stage joint disease, but implant failure remains a major complication. Aseptic loosening, driven by periprosthetic osteolysis, is a primary factor limiting the longevity of THR. Early detection of osteolysis is particularly challenging because patients are often asymptomatic until the condition r...

Compliant Intramedullary Stems for Joint Reconstruction.

IEEE journal of translational engineering in health and medicine | 2024 | Mccullough JA, Peterson BT, Upfill-Brown AM, Hardin TJ

[Indexed for MEDLINE] 3. J Arthroplasty. 2023 Jul;38(7 Suppl 2):S369-S375. doi: 10.1016/j.arth.2023.02.083. Epub 2023 Mar 6. Outcomes are Compromised When Revising Patellofemoral Arthroplasties for Patellar Component Failures. Treu EA(1), Frandsen JJ(1), Al Saidi NN(2), Blackburn BE(1), Pelt CE(1), Anderson LA(1), Gililland JM(1). Author information: (1)Department of Orthopaedi...

Clinical outcomes of total joint arthroplasty in patients with bowel ostomies.

Archives of orthopaedic and trauma surgery | 2024 | Katzman JL, Passano B, Manjunath A, Habibi AA

[Indexed for MEDLINE] 5. J Shoulder Elbow Surg. 2017 Mar;26(3):443-449. doi: 10.1016/j.jse.2016.08.009. Epub 2016 Oct 10. Revisions for aseptic glenoid component loosening after anatomic shoulder arthroplasty. Aibinder WR(1), Schoch B(2), Schleck C(1), Sperling JW(3), Cofield RH(1). Author information: (1)Department of Orthopaedic Surgery, Mayo Clinic, Rochester, MN, USA. (2)De...

Osteoporosis and Total Knee Arthroplasty: Higher 5-Year Implant-Related Complications.

The Journal of arthroplasty | 2024 | Harris AB, Lantieri MA, Agarwal AR, Golladay GJ

[Indexed for MEDLINE] 20. Biomed Mater Eng. 2019;30(3):297-308. doi: 10.3233/BME-191053. Breakage of metal hip arthroplasty components: Retrieval and structural analysis. Łapaj Ł(1), Woźniak W(1), Wiśniewski T(2), Rozwalka J(2), Paczesny Ł(3), Zabrzyński J(3), Janusz P(4), Kruczyński J(1). Author information: (1)Department of General Orthopaedics, Musculoskeletal Oncology and T...

Aseptic loosening - knee arthroplasty

Radiopaedia.org | 2024 | Domenico Nicoletti

Aseptic loosening of elbow arthroplasty with recurrent trauma

Radiopaedia.org | 2024 | Evangeline Collins

Aseptic Loosening

Essentials in Total Knee Arthroplasty | 2024 | Zachary Post

Outcomes are Compromised When Revising Patellofemoral Arthroplasties for Patellar Component Failures.

The Journal of arthroplasty | 2023 | Treu EA, Frandsen JJ, Al Saidi NN, Blackburn BE

[Indexed for MEDLINE] 4. Arch Orthop Trauma Surg. 2024 Aug;144(8):3823-3831. doi: 10.1007/s00402-024-05453-9. Epub 2024 Aug 8. Clinical outcomes of total joint arthroplasty in patients with bowel ostomies. Katzman JL(1), Passano B(2), Manjunath A(1), Habibi AA(1), Schwarzkopf R(1), Davidovitch RI(3). Author information: (1)Department of Orthopedic Surgery, NYU Langone Health, T...

Camouflage uncovered: what should happen next?

The bone & joint journal | 2023 | Wilton T, Skinner JA, Haddad FS

[Indexed for MEDLINE] Conflict of interest statement: F. S. Haddad is the Editor-in-Chief of The Bone & Joint Journal and Bone & Joint Open. F. S. Haddad reports multiple research study grants from Stryker, Smith & Nephew, Corin, International Olympic Committee, and the National Institutes of Health Research, royalties from Smith & Nephew, Stryker, Corin, and MatOrtho, consulti...

Contemporary mortality rate and outcomes in nonagenarians after aseptic revision hip and knee arthroplasty.

The bone & joint journal | 2023 | Dagneaux L, Amundson AW, Larson DR, Pagnano MW

[Indexed for MEDLINE] Conflict of interest statement: M. P. Abdel reports royalties related to hip and knee implants from Stryker, royalties from OsteoRemedies, and publishing royalties from Springer, all of which are unrelated to this study. M. P. Abdel is also on the Board of Directors of AAHKS, IOEN, and Mid-America. A. Amundson reports royalties from Wolters Kluwer, and sto...

Revision Knee Arthroplasty for “Pain Without Loosening” Versus “Aseptic Loosening”

Advances in Orthopedic Surgery of the Knee | 2023 | E. Carlos Rodríguez-Merchán

Varus Collapse in Total Knee Arthroplasty: Does Fixation or Bone Fail First?

The Journal of arthroplasty | 2022 | Cox ZC, Green CC, Otero JE, Mason JB

[Indexed for MEDLINE] 7. Oper Orthop Traumatol. 2017 Jun;29(3):207-219. doi: 10.1007/s00064-017-0492-x. Epub 2017 Apr 25. [Aseptic loosening of total ankle replacement and conversion to ankle arthrodesis]. [Article in German] Wimmer MD(1), Hettchen M(2), Ploeger MM(2), Hintermann B(3), Wirtz DC(2), Barg A(4)(5). Author information: (1)Klinik und Poliklinik für Orthopädie und Un...

Metaphyseal sleeves in revision total knee arthroplasties: Computational analysis of bone remodeling.

The Knee | 2022 | Nogueira P, Folgado J, Quental C, Gamelas J

[Indexed for MEDLINE] Conflict of interest statement: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. 12. J Arthroplasty. 2020 Apr;35(4):976-980. doi: 10.1016/j.arth.2019.11.038. Epub 2019 Nov 30. Contemporary Total Hip and...

The lifetime revision risk of unicompartmental knee arthroplasty.

The bone & joint journal | 2022 | Tay ML, Young SW, Frampton CM, Hooper GJ

[Indexed for MEDLINE] 18. Bone Joint J. 2023 Jun 1;105-B(6):649-656. doi: 10.1302/0301-620X.105B6.BJJ-2022-1368.R1. Contemporary mortality rate and outcomes in nonagenarians after aseptic revision hip and knee arthroplasty. Dagneaux L(1), Amundson AW(2), Larson DR(3), Pagnano MW(1), Berry DJ(1), Abdel MP(1). Author information: (1)Department of Orthopedic Surgery, Mayo Clinic,...

Implant Movement Analysis (IMA), A New CT Based Technique for Diagnosis of Aseptic Loosening of Total Knee Arthroplasty

Orthopedic Research Online Journal | 2021 | Per Wretenberg

Outcomes of Cementless-Backed Patellar Components.

The journal of knee surgery | 2020 | Harwin SF, DeGouveia W, Sodhi N, Gold PA

[Indexed for MEDLINE] Conflict of interest statement: None declared. 2. IEEE J Transl Eng Health Med. 2024 Feb 12;12:314-327. doi: 10.1109/JTEHM.2024.3365305. eCollection 2024. Compliant Intramedullary Stems for Joint Reconstruction. Mccullough JA(1), Peterson BT(2), Upfill-Brown AM(2), Hardin TJ(3), Hopkins JB(1), Soohoo NF(2), Clites TR(1)(4). Author information: (1)Departmen...

Contemporary Total Hip and Total Knee Arthroplasty Results in Patients with Hemochromatosis.

The Journal of arthroplasty | 2020 | Limberg AK, Chalmers BP, Perry KI, Lewallen DG

[Indexed for MEDLINE] 13. J Arthroplasty. 2019 Jan;34(1):145-150. doi: 10.1016/j.arth.2018.09.003. Epub 2018 Sep 12. Direct Anterior Approach and Perioperative Fracture With a Single-Taper Wedge Femoral Component. Greco NJ(1), Lombardi AV Jr(2), Morris MJ(1), Hobbs GR(3), Berend KR(1). Author information: (1)Joint Implant Surgeons, Inc., New Albany, OH; White Fence Surgical Sui...

Association of NLRP3 and CARD8 Inflammasome Polymorphisms With Aseptic Loosening After Primary Total Hip Arthroplasty

Journal of Orthopaedic Research | 2020 | Blaž Mavčič, Vane Antolič, Vita Dolžan

ABSTRACTOur aim was to investigate the association of inflammasome polymorphisms NLRP3 rs35829419 (p. Q705K) and CARD8 rs2043211 (p. C10X) with aseptic loosening of total hip endoprostheses. We asked whether patients with the loosening of total hip arthroplasty earlier than 15 years after primary implantation had a higher proportion of the polymorphisms Q705K and C10X in compar...

Direct Anterior Approach and Perioperative Fracture With a Single-Taper Wedge Femoral Component.

The Journal of arthroplasty | 2019 | Greco NJ, Lombardi AV Jr, Morris MJ, Hobbs GR

[Indexed for MEDLINE] 14. Musculoskelet Surg. 2019 Aug;103(2):173-179. doi: 10.1007/s12306-018-0573-5. Epub 2018 Oct 16. The biological acetabular reconstruction with bone allografts in hip revision arthroplasty. Busanelli L(1), Castagnini F(2), Bordini B(3), Stea S(3), Calderoni PP(1), Toni A(1). Author information: (1)Ortopedia-Traumatologia e Chirurgia protesica e dei reimpi...

The biological acetabular reconstruction with bone allografts in hip revision arthroplasty.

Musculoskeletal surgery | 2019 | Busanelli L, Castagnini F, Bordini B, Stea S

[Indexed for MEDLINE] 15. J Bone Joint Surg Am. 2017 May 17;99(10):873-881. doi: 10.2106/JBJS.16.00423. Modular Fluted Tapered Stems in Aseptic Revision Total Hip Arthroplasty. Abdel MP(1), Cottino U, Larson DR, Hanssen AD, Lewallen DG, Berry DJ. Author information: (1)1Departments of Orthopaedic Surgery (M.P.A., U.C., A.D.H., D.G.L., and D.J.B.) and Health Sciences Research (D...

Breakage of metal hip arthroplasty components: Retrieval and structural analysis.

Bio-medical materials and engineering | 2019 | Łapaj Ł, Woźniak W, Wiśniewski T, Rozwalka J

[Indexed for MEDLINE]

Knee Bony Defects Reconstruction in Revision Total Knee Arthroplasty for Aseptic Loosening

Orthopedic Research Online Journal | 2019 | Ahmed A Khalifa

Revisions for aseptic glenoid component loosening after anatomic shoulder arthroplasty.

Journal of shoulder and elbow surgery | 2017 | Aibinder WR, Schoch B, Schleck C, Sperling JW

[Indexed for MEDLINE] 6. J Arthroplasty. 2022 Jan;37(1):162-167. doi: 10.1016/j.arth.2021.09.012. Epub 2021 Sep 28. Varus Collapse in Total Knee Arthroplasty: Does Fixation or Bone Fail First? Cox ZC(1), Green CC(1), Otero JE(1), Mason JB(1), Martin JR(2). Author information: (1)OrthoCarolina Hip and Knee Center, Charlotte, NC. (2)Vanderbilt University Medical Center, Nashville...

[Aseptic loosening of total ankle replacement and conversion to ankle arthrodesis].

Operative Orthopadie und Traumatologie | 2017 | Wimmer MD, Hettchen M, Ploeger MM, Hintermann B

[Indexed for MEDLINE] 8. Bone Joint J. 2023 Mar 1;105-B(3):221-226. doi: 10.1302/0301-620X.105B3.BJJ-2023-0145. Camouflage uncovered: what should happen next? Wilton T(1), Skinner JA(2), Haddad FS(3)(4). Author information: (1)Royal Derby Hospital, Derby, UK. (2)Institute of Orthopaedics, Royal National Orthopaedic Hospital, London, UK. (3)University College London Hospitals NH...

Modular Fluted Tapered Stems in Aseptic Revision Total Hip Arthroplasty.

The Journal of bone and joint surgery. American volume | 2017 | Abdel MP, Cottino U, Larson DR, Hanssen AD

[Indexed for MEDLINE] 16. J Am Acad Orthop Surg. 2017 Aug;25(8):e166-e174. doi: 10.5435/JAAOS-D-15-00479. Revision Total Elbow Arthroplasty. Ramirez MA(1), Cheung EV, Murthi AM. Author information: (1)From the Department of Orthopaedic Surgery, MedStar Union Memorial Hospital, Baltimore, MD (Dr. Ramirez and Dr. Murthi) and the Department of Orthopaedic Surgery, Stanford Univers...

Periprosthetic Bone Remodeling After Novel Short-Stem Neck-Sparing Total Hip Arthroplasty.

The Journal of arthroplasty | 2016 | Tran P, Zhang BX, Lade JA, Pianta RM

[Indexed for MEDLINE] 11. Knee. 2022 Aug;37:10-19. doi: 10.1016/j.knee.2022.05.006. Epub 2022 Jun 2. Metaphyseal sleeves in revision total knee arthroplasties: Computational analysis of bone remodeling. Nogueira P(1), Folgado J(2), Quental C(3), Gamelas J(4). Author information: (1)IDMEC, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal. Electronic address:...

Risk Factors for Aseptic Loosening Following Total Hip Arthroplasty

Recent Advances in Arthroplasty | 2012 | Scott J., Andrew Gordon, J. Mark

Evidence Linking Elevated Oxidative Stress and Aseptic Loosening of Hip Arthroplasty

Recent Advances in Arthroplasty | 2012 | Plamen Kinov, Peter Tivchev

Is cementing technique the cause of early aseptic loosening of the tibial component in total knee arthroplasty? A report of 22 failed tibial components

Orthopedic Review | 2011

Role of free radicals in aseptic loosening of hip arthroplasty

Journal of Orthopaedic Research | 2006 | Plamen Kinov, Andreas Leithner, Roman Radl, Koppany Bodo

AbstractFibrous pseudocapsule around hip implants is an invariable finding at revision operations and is believed to release inflammatory mediators that stimulate bone resorption. Reactive oxygen species have been proposed to be causative factors in various disorders with tissue fibrosis. We were interested in investigating whether aseptic loosening is connected with high oxida...

Radionuclide bone scintigraphy in the detection of significant complications after total knee joint replacement.

Clinical radiology | 2001 | Smith SL, Wastie ML, Forster I

[Indexed for MEDLINE] 10. J Arthroplasty. 2016 Nov;31(11):2530-2535. doi: 10.1016/j.arth.2016.04.023. Epub 2016 Apr 30. Periprosthetic Bone Remodeling After Novel Short-Stem Neck-Sparing Total Hip Arthroplasty. Tran P(1), Zhang BX(1), Lade JA(1), Pianta RM(1), Unni RP(1), Haw CS(1). Author information: (1)Department of Orthopaedic Surgery, Footscray Hospital, Western Health, Fo...

Revision resurfacing knee arthroplasty for aseptic loosening

Archives of Orthopaedic and Trauma Surgery | 1998 | A. Karbowski, A. Eckardt, M. Schwitalle, J. Heine

A Case Report of Metallosis-Related Aseptic Loosening of Primary Total Knee Arthroplasty Implant Managed with Revision Total Knee Arthroplasty

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