Evidence Search

High Tibial Osteotomy for Medial Compartment Knee Osteoarthritis : A Randomized Trial With Parallel Preference Arm.

Annals of internal medicine | 2025 | Birmingham TB, Primeau CA, Moyer RF, Bryant DM

[Indexed for MEDLINE] Conflict of interest statement: Disclosures: Disclosure forms are available with the article online. 15. Infection. 2018 Feb;46(1):55-68. doi: 10.1007/s15010-017-1085-1. Epub 2017 Oct 30. Tubercular prosthetic joint infection: two case reports and literature review. Veloci S(1), Mencarini J(1), Lagi F(1), Beltrami G(2), Campanacci DA(2)(3), Bartoloni A(1)(...

Safety and effectiveness of intraosseous regional prophylactic antibiotics in total knee arthroplasty: a systematic review and meta-analysis.

Archives of orthopaedic and trauma surgery | 2024 | Yu M, Wei Z, Yang X, Xu Y

[Indexed for MEDLINE] Conflict of interest statement: Declarations Conflict of interest All authors complete the ICMJE Uniform Disclosure Form for Potential Conflicts of Interest. Ethical approval All studies included in this review declared ethical approval. 6. Am J Sports Med. 2026 Jan;54(1):223-229. doi: 10.1177/03635465251357593. Epub 2026 Jan 1. Injectable Peptide Therapy:...

Antibiotic Therapy for 6 or 12 Weeks for Prosthetic Joint Infection.

The New England journal of medicine | 2021 | Bernard L, Arvieux C, Brunschweiler B, Touchais S

[Indexed for MEDLINE] 2. J Orthop Translat. 2022 Dec 7;38:241-255. doi: 10.1016/j.jot.2022.10.015. eCollection 2023 Jan. Teriparatide ameliorates articular cartilage degradation and aberrant subchondral bone remodeling in DMM mice. Li G(1)(2), Liu S(1)(2), Chen Y(1)(2), Xu H(1)(2), Qi T(1)(2), Xiong A(1)(2), Wang D(1)(2), Yu F(1)(2), Weng J(1)(2), Zeng H(1)(2). Author informati...

Injectable Peptide Therapy: A Primer for Orthopaedic and Sports Medicine Physicians.

The American journal of sports medicine | 2026 | Mayfield CK, Bolia IK, Feingold CL, Lin EH

[Indexed for MEDLINE] Conflict of interest statement: One or more of the authors has declared the following potential conflict of interest or source of funding: J.N.L. has received speaking fees from Stryker and hospitality payments from Innocoll Biotherapeutics. G.R.H. has received consulting fees from Arthrex. S.C.G. has received speaking fees from Arthrex; has received consu...

Bone loss in aseptic revision total knee arthroplasty: management and outcomes.

Knee surgery & related research | 2022 | Bieganowski T, Buchalter DB, Singh V, Mercuri JJ

Conflict of interest statement: TB, DB, VS, VA, and JR have nothing to disclose. JM is a paid consultant for Medacta. RS is a paid consultant for Intellijoint and Smith&Nephew; holds IP royalties in Smith&Nephew; and holds stock options in Gauss Surgical, Intellijoint, and PSI. 5. Arch Orthop Trauma Surg. 2024 Sep;144(9):4233-4245. doi: 10.1007/s00402-024-05513-0. Epub 2024 Sep...

Total knee arthroplasty in the face of a previous tuberculosis infection of the knee: what do we know in 2018?

Expert review of medical devices | 2018 | Sultan AA, Cantrell WA, Rose E, Surace P

[Indexed for MEDLINE] 18. Sci Rep. 2020 Mar 4;10(1):3975. doi: 10.1038/s41598-020-60464-x. Tibial subchondral trabecular bone micromechanical and microarchitectural properties are affected by alignment and osteoarthritis stage. Renault JB(1)(2), Carmona M(3)(4), Tzioupis C(3), Ollivier M(5)(3), Argenson JN(5)(3), Parratte S(5)(3)(6), Chabrand P(5)(3). Author information: (1)Aix...

Didymin halts knee osteoarthritis progression by targeting the GSK3B/5-LOX/11-HETE pathway to suppress chondrocyte ferroptosis.

Phytomedicine : international journal of phytotherapy and phytopharmacology | 2026 | Zhou Y, Xue Y, Jiang M, Weiyang W

[Indexed for MEDLINE] Conflict of interest statement: Declaration of competing interest The authors declare no competing interests. 12. Phytomedicine. 2025 Nov 25;148:157431. doi: 10.1016/j.phymed.2025.157431. Epub 2025 Oct 20. Integrative Metabolomics and Pharmacology Reveal Guzhi Zengsheng Zhitongwan's Mechanism in Knee Osteoarthritis. Zhou Y(1), Ng L(2), Chen Z(3), Qin L(4),...

Injury and obesity differentially and synergistically induce dysregulation of synovial immune cells in osteoarthritis.

Annals of the rheumatic diseases | 2025 | Harasymowicz NS, Harissa Z, Rashidi N, Lenz K

[Indexed for MEDLINE] Conflict of interest statement: Competing interests None declared. 9. Stem Cell Res Ther. 2025 May 9;16(1):235. doi: 10.1186/s13287-025-04366-7. Subchondral injection of human umbilical cord mesenchymal stem cells ameliorates knee osteoarthritis by inhibiting osteoblast apoptosis and TGF-beta activity. Wu C(#)(1)(2)(3), Xu H(#)(1)(4), Wu Z(#)(2)(5), Huang...

Subchondral injection of human umbilical cord mesenchymal stem cells ameliorates knee osteoarthritis by inhibiting osteoblast apoptosis and TGF-beta activity.

Stem cell research & therapy | 2025 | Wu C, Xu H, Wu Z, Huang H

[Indexed for MEDLINE] Conflict of interest statement: Declarations. Ethics approval and consent to participate: The procedures of this study entitled ‘Subchondral injection of human umbilical cord mesenchymal stem cells ameliorates knee osteoarthritis by inhibiting osteoblast apoptosis and TGF-beta activity’ were approved by the Experimental Animal Ethics Committee of Zhejiang...

More severe microdamage and micromechanical alterations: altered subchondral bone remodeling in varus knee osteoarthritis with osteoporosis.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA | 2025 | Zeng ZJ, PengPeng, Huang CL, Yao FM

[Indexed for MEDLINE] Conflict of interest statement: Declarations. Conflict of interest: None. 11. Phytomedicine. 2026 Feb;151:157789. doi: 10.1016/j.phymed.2026.157789. Epub 2026 Jan 7. Didymin halts knee osteoarthritis progression by targeting the GSK3B/5-LOX/11-HETE pathway to suppress chondrocyte ferroptosis. Zhou Y(1), Xue Y(1), Jiang M(1), Weiyang W(2), Chen W(3), Zhang...

Integrative Metabolomics and Pharmacology Reveal Guzhi Zengsheng Zhitongwan's Mechanism in Knee Osteoarthritis.

Phytomedicine : international journal of phytotherapy and phytopharmacology | 2025 | Zhou Y, Ng L, Chen Z, Qin L

[Indexed for MEDLINE] Conflict of interest statement: Declaration of competing interest We declare that all authors have no conflicts of interest that could affect the objectivity of the research. We have fully disclosed any potential conflicts of interest and ensure that these conflicts do not influence the design, execution, or reporting of the study. 13. J Orthop Translat. 2...

Predicting periprosthetic joint Infection: Evaluating supervised machine learning models for clinical application.

Journal of orthopaedic translation | 2025 | Dragosloveanu S, Vulpe DE, Andrei CA, Nedelea DG

Conflict of interest statement: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. 14. Ann Intern Med. 2025 Sep;178(9):1238-1248. doi: 10.7326/ANNALS-25-00920. Epub 2025 Jul 29. High Tibial Osteotomy for Medial Compartment Knee Osteoarthritis : A Randomized Tr...

Optimizing orthopedic care: Insights from a comprehensive analysis of day case total knee replacement

Journal of Orthopaedic Reports | 2025 | Bashir R. Alenazi, Ghassan H. Hakeem, Mohammed A. Alruwaili, Saad I. Alshammari

KLF2 Inhibits Ferroptosis and Improves Mitochondrial Dysfunction in Chondrocyte Through SIRT1/GPX4 Signaling to Improve Osteoarthritis.

Drug development research | 2024 | Shi J, Chen L, Wang X, Ma X

[Indexed for MEDLINE] 4. Knee Surg Relat Res. 2022 Jun 20;34(1):30. doi: 10.1186/s43019-022-00158-y. Bone loss in aseptic revision total knee arthroplasty: management and outcomes. Bieganowski T(1), Buchalter DB(1), Singh V(1), Mercuri JJ(2), Aggarwal VK(1), Rozell JC(1), Schwarzkopf R(3). Author information: (1)Division of Adult Reconstruction, Department of Orthopedic Surgery...

Total Knee Replacement in a Young Patient with Valgus Knee Osteoarthritis: A Case Report

Journal of Orthopaedic Case Reports | 2024 | Pervez Ahsan, Md. Shafiul Ezaz, Israt Jahan, Nusrat Sharmin Asma

Introduction: Valgus deformity is characterized by an outward angulation of the knee joint. The most common cause of valgus deformity is osteoarthritis (OA), a prevalent progressive joint disease that causes chronic pain and functional limitations. Total knee replacement (TKR) is rarely done in patients with grade-I valgus deformity and young age. To the best of our knowledge,...

Teriparatide ameliorates articular cartilage degradation and aberrant subchondral bone remodeling in DMM mice.

Journal of orthopaedic translation | 2023 | Li G, Liu S, Chen Y, Xu H

Conflict of interest statement: The authors declare that they have no conflict of interest. 3. Drug Dev Res. 2024 Nov;85(7):e70015. doi: 10.1002/ddr.70015. KLF2 Inhibits Ferroptosis and Improves Mitochondrial Dysfunction in Chondrocyte Through SIRT1/GPX4 Signaling to Improve Osteoarthritis. Shi J(1), Chen L(1), Wang X(1), Ma X(1). Author information: (1)Orthopedic Department, H...

Tubercular prosthetic joint infection: two case reports and literature review.

Infection | 2018 | Veloci S, Mencarini J, Lagi F, Beltrami G

[Indexed for MEDLINE] 16. NMR Biomed. 2006 Nov;19(7):822-54. doi: 10.1002/nbm.1063. Quantitative MRI of cartilage and bone: degenerative changes in osteoarthritis. Eckstein F(1), Burstein D, Link TM. Author information: (1)Institute of Anatomy and Musculoskeletal Research, Paracelsus Private Medical University (PMU), A-5020 Salzburg, Austria. felix.eckstein@pmu.ac.at Magnetic r...

Probiotics Inhibit Cartilage Damage and Progression of Osteoarthritis in Mice.

Calcified tissue international | 2023 | Sophocleous A, Azfer A, Huesa C, Stylianou E

[Indexed for MEDLINE] Conflict of interest statement: Professor Ralston reports funding to his institution from Abbvie, Alexion, Amgen, Bristol Myers Squibb, Cellgene, Janssen-Cilag, Kyowa Kirin, Novartis, Pfizer, Sanofi-Genzyme, Sandoz, UCB, and Thornton and Ross; and research funding to his institution from Astra Zeneca and UCB, outside the submitted work. Dr Sophocleous and...

orthopaedic | orthopedic, adj.

Oxford English Dictionary | 2023

Dark-light cycle disrupts bone metabolism and suppresses joint deterioration in osteoarthritic rats.

Arthritis research & therapy | 2022 | Song X, Zhao M, Tang J, Ma T

[Indexed for MEDLINE] Conflict of interest statement: The authors declare that they have no competing interests. 8. Ann Rheum Dis. 2025 Jun;84(6):1033-1044. doi: 10.1016/j.ard.2025.03.001. Epub 2025 Apr 4. Injury and obesity differentially and synergistically induce dysregulation of synovial immune cells in osteoarthritis. Harasymowicz NS(1), Harissa Z(2), Rashidi N(3), Lenz K(...

The causal association between bone mineral density and risk of osteoarthritis: A Mendelian randomization study.

Frontiers in endocrinology | 2022 | Jiang L, Jiang Y, Wang A, Wu C

[Indexed for MEDLINE] Conflict of interest statement: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. 20. Calcif Tissue Int. 2023 Jan;112(1):66-73. doi: 10.1007/s00223-022-01030-7. Epub 2022 Oct 19. Probiotics Inhibit Cartilage Damage and Progression of O...

Knee Mechanics related to Knee Replacement For Postgraduate Orthopaedic Exams

OrthoMedia | 2022

Knee Examination for Orthopaedic Exams (Part 2 )

OrthoMedia | 2022

Principles of knee replacement for Orthopaedic Exams

OrthoMedia | 2022

Osteotomies around the Knee for Orthopaedic Exams

OrthoMedia | 2022

Management of Valgus Knee for Orthopaedic Exams

OrthoMedia | 2022

Quantitative MRI of cartilage and bone: degenerative changes in osteoarthritis.

NMR in biomedicine | 2006 | Eckstein F, Burstein D, Link TM

[Indexed for MEDLINE] 17. Expert Rev Med Devices. 2018 Oct;15(10):717-724. doi: 10.1080/17434440.2018.1520633. Epub 2018 Sep 28. Total knee arthroplasty in the face of a previous tuberculosis infection of the knee: what do we know in 2018? Sultan AA(1), Cantrell WA(1), Rose E(1), Surace P(1), Samuel LT(1), Chughtai M(1), Khlopas A(1), Newman JM(2), Moskal JT(3), Mont MA(1)(4)....

Tibial subchondral trabecular bone micromechanical and microarchitectural properties are affected by alignment and osteoarthritis stage.

Scientific reports | 2020 | Renault JB, Carmona M, Tzioupis C, Ollivier M

[Indexed for MEDLINE] Conflict of interest statement: The authors declare no competing interests. 19. Front Endocrinol (Lausanne). 2023 Jan 11;13:1021083. doi: 10.3389/fendo.2022.1021083. eCollection 2022. The causal association between bone mineral density and risk of osteoarthritis: A Mendelian randomization study. Jiang L(1)(2), Jiang Y(3), Wang A(4), Wu C(5), Shen Y(6). Aut...

TB Knee: Uncommon Presentation of Bone TB

Journal of Medical Science And clinical Research | 2020 | Dr Sunil Kumar Agarwalla

Computer-Assisted Orthopedic Surgery for Hip Osteotomy

Computer Assisted Orthopaedic Surgery for Hip and Knee | 2018 | Masaki Takao, Takashi Sakai, Hidetoshi Hamada, Nobuhiko Sugano

Chapter-06 Total Knee Arthroplasty for the Stiff Knee

Mastering Orthopedic Techniques Total Knee Arthroplasty | 2010 | Rajesh Malhotra

Computer-assisted orthopaedic surgery: minimally invasive hip and knee reconstruction

Orthopedic Clinics of North America | 2004 | Anthony M DiGioia, Sorin Blendea, Branislav Jaramaz

Orthopedic Disorders

Orthopaedic Nursing | 1993 | Mary Ann Gray

Camp Introduces Orthopedic Bootee

Orthopaedic Nursing | 1986 | &NA;

Knee

Rapid Orthopedic Diagnosis