Orthonotes
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EX-000001·DNB Ortho·2014

Describe the stages of fracture healing. List the factors influencing fracture healing. What are the causes of nonunion?

Wiki topic: Fracture Healing — Biology & Timelines

Answer

Fracture Healing and Nonunion

DNB Orthopaedics • June 2014 • Paper I • 10 Marks

Introduction

Fracture healing is a complex biological process by which a broken bone restores its continuity, mechanical strength and function. Bone is unique because healing occurs predominantly by regeneration rather than scar formation, with eventual restoration of normal lamellar architecture.

Successful fracture healing requires an appropriate interaction between biology, vascularity and mechanical stability.

Core concept

Good biology + adequate blood supply + appropriate stability = predictable fracture union.

Classification of Fracture Healing

Fracture healing is broadly classified into:

Feature Primary / Direct Healing Secondary / Indirect Healing
Stability Absolute stability Relative stability
Interfragmentary movement Minimal Controlled micromotion present
Callus Absent or minimal Prominent callus formation
Biological mechanism Direct osteonal remodelling Intramembranous + endochondral ossification
Typical examples Lag screw fixation, compression plating Cast, intramedullary nail, bridge plating, external fixation


Describe the stages of fracture healing. List the factors influencing fracture healing. What are the causes of nonunion?


I. Primary / Direct Fracture Healing

Primary fracture healing occurs when the fracture is anatomically reduced and maintained under absolute stability with very low interfragmentary strain.

There is little or no external callus formation.

A. Contact Healing

  • Occurs when cortical ends are in near-perfect contact.
  • Osteoclasts cross the fracture line forming cutting cones.
  • Capillaries…

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