Describe the pathology of secondary deposits in bone, write on the mode of spread and clinical manifestations, write the management of secondary deposits with suitable examples.

Management of a case of carcinoma lung with pathological fracture at subtrochanteric level: a) Management rationale and options. [5] b) What is the role of histopathology and/or immunohistochemistry in decision making? [5]

Metastatic disease of bone

Osteoblastic secondaries of spine.

Spinal metastasis: list causes, discuss clinical presentation and investigations & management.