Oncologic principles: accurate diagnosis, staging (MRI, PET/CT), biopsy planning, and **wide margins**. Indications: resectable tumors with adequate soft-tissue coverage and neurovascular preservation; good chemo response when applicable. Reconstruction options: endoprosthesis (modular/mega), biological (intercalary grafts, vascularized fibula, allograft), arthrodesis. Complications: infection, flap failure, nonunion, prosthetic loosening, local recurrence. Multidisciplinary planning is essential; amputation indicated when margins/functional outcomes are inferior.
What is the primary goal of limb salvage surgery (LSS) in the treatment of bone tumors?
Which imaging modality is considered essential for staging bone tumors prior to limb salvage surgery?
In the context of limb salvage surgery, which surgical margin is considered the oncological target for high-grade bone sarcomas?
What is the primary reason for using neoadjuvant chemotherapy in the management of osteosarcoma?
Which of the following complications is most commonly associated with limb salvage surgery?
What is the recommended surgical margin thickness for high-grade sarcomas after effective neoadjuvant chemotherapy?
Which of the following tumors is most commonly treated with limb salvage surgery?
Which of the following indications would most likely warrant amputation instead of limb salvage surgery?
Which reconstruction option is often used in limb salvage surgery for bone tumors?
What is the local recurrence rate after limb salvage surgery at specialist centers for high-grade bone sarcomas?