Osteochondral Defects — Autologous Chondrocyte Implantation (ACI)
Cartilage defects cause pain, swelling, mechanical symptoms; poor intrinsic healing. ACI: two-stage procedure — harvest cartilage → culture chondrocytes → reimplant under periosteal flap/biomatrix. Indications: symptomatic focal cartilage defects >2 cm² in young active patients. Alternatives: microfracture, OATS, osteochondral allograft. Complications: graft hypertrophy, delamination, failure.
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1Practised by MCQ
10What is the primary indication for Autologous Chondrocyte Implantation (ACI)?
mcqWhat is the main advantage of third-generation ACI (MACI) over first-generation ACI?
mcqWhich of the following is a contraindication for ACI?
mcqDuring the first stage of ACI, where is the cartilage harvested from?
mcqWhat is the ideal defect size for ACI?
mcqWhich complication is commonly associated with first-generation ACI?
mcqWhat is the main purpose of the collagen membrane in second-generation ACI?
mcqWhat is the primary mechanism of action for ACI?
mcqWhich of the following is a common alternative to ACI for treating cartilage defects?
mcqWhat is the key postoperative consideration following ACI?