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Periprosthetic Joint Infection — Principles

Diagnosis uses consensus criteria (MSIS/ICM) combining major and minor criteria. Classify by timing: early (24 mo) — guides biofilm maturity and strategy. Treatment options: DAIR (debridement, antibiotics, implant retention), one‑stage or two‑stage revision; chronic suppression in poor hosts. Principles: radical debridement, exchange modular parts, biofilm‑active antibiotics (e.g., rifampicin combinations for staph). Prevention bundle: laminar flow, antibiotic prophylaxis, skin prep, glycemic co...

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