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Overview & Anatomy
The Maisonneuve fracture is a proximal fibular fracture associated with a disruption of the ankle syndesmosis and interosseous membrane, with or without a medial-sided ankle injury. It is a high-energy equivalent ankle injury that is frequently missed on initial presentation because the fracture is remote from the ankle, and plain ankle radiographs may appear deceptively benign.
Named after Jules Germain FranΓ§ois Maisonneuve (1840), who described the spiral fracture of the proximal fibula caused by external rotation of the foot
The mechanism is external rotation of the foot with a fixed leg β force propagates proximally through the interosseous membrane from a medial ankle injury to fracture the proximal fibula
The interosseous membrane tears from distal to proximal up to the level of the fracture
Medial-sided injury is almost always present: deltoid ligament rupture, medial malleolus fracture, or both
The anterior inferior tibiofibular ligament (AITFL) and posterior inferior tibiofibular ligament (PITFL) are disrupted β complete syndesmotic instability results
The ankle mortise is unstable despite a normal or near-normal appearance on ankle radiographs β this is the key diagnostic pitfall
The Maisonneuve fracture represents the most proximal variant of the Supination-External Rotation (SER) or Pronation-External Rotation (PER) patterns in the Lauge-Hansen classification. Understanding this context clarifies why the syndesmosis is always disrupted.
Maisonneuve = Pronation-External Rotation (PER) pattern β medial injury occurs first, then force propagates through interosseous membrane
The entire interosseous membrane from the ankle to the fibula fracture is disrupted β this is why the ankle is completely unstable despite the fracture being at the knee level
Weber classification: Maisonneuve = Weber C (fibula fracture above syndesmosis) β syndesmosis always disrupted in Weber C injuries
Diagnosis β Clinical & Radiographic
Clinical examination: ankle pain and swelling; medial ankle tenderness (deltoid ligament or medial malleolus); proximal fibula pain and tenderness β ALWAYS palpate the entire fibula in any ankle injury; positive external rotation stress test of ankle
Squeeze test (Hopkinson): compression of fibula and tibia at mid-calf β pain at ankle or along interosseous membrane = positive; suggests syndesmotic disruption
External rotation stress test: foot in neutral, externally rotate β reproduction of ankle pain; lateral talar shift on stress radiograph confirms instability
Plain radiographs: always include full-length tibia-fibula views when Maisonneuve suspected; standard ankle views may show: widened medial clear space (>4 mm), widened syndesmosis (>5 mm at 1 cm above plafond on AP), tibiofibular overlap <10 mm on AP or <1 mm on mortise, medial malleolus fracture
Medial clear space >4 mm = deltoid rupture or medial malleolus fracture = ankle instability until proven otherwise
CT scan: useful to define posterior malleolus involvement, fibula fracture comminution, and articular congruity; assess for anterolateral tibial lip fractures (Chaput fragment)
MRI: can confirm deltoid ligament and syndesmotic ligament integrity; useful when clinical diagnosis uncertain
Management
The Maisonneuve fracture is an unstable ankle injury requiring surgical stabilisation of the syndesmosis. The proximal fibula fracture itself rarely requires direct fixation.
Medial malleolus fracture (if present): ORIF with lag screws or tension band wiring β restores medial buttress; performed before syndesmotic fixation
Deltoid ligament rupture: if medial malleolus intact but deltoid torn β repair vs no repair is debated; most contemporary evidence supports repair of deltoid in presence of syndesmotic instability to prevent residual medial instability
Syndesmotic stabilisation: mandatory in all Maisonneuve fractures β the proximal fracture = complete syndesmotic disruption
Reduction of syndesmosis: reduce fibula into tibial incisura anatomically under direct vision or fluoroscopy; clamp from fibula to tibia with ankle in dorsiflexion; confirm reduction on mortise view β fibula must be reduced into incisura; CT can confirm post-reduction congruity
Syndesmotic Fixation Options:
Method
Technique
Notes
Syndesmotic screw (positional)
3.5 or 4.5 mm cortical screw through fibula, across syndesmosis into tibia; 2β4 cortices; 2β4 cm above plafond
Traditional gold standard; requires removal before full weight bearing (or may loosen/break); tricortical vs quadricortical debated
TightRope / suture button
Flexible fixation through fibula and tibia with cortical buttons
Allows physiological motion; no routine removal needed; increasingly favoured; equivalent or superior outcomes to screw in RCTs
Two screws
Two syndesmotic screws for highly unstable injuries
Increased rotational stability; both removed if symptomatic
Ankle must be in dorsiflexion during syndesmotic fixation β prevents overtightening and malreduction of fibula in dorsiflexion; plantarflexion at time of screw insertion risks fibula being fixed in an anterior position
Proximal fibula fracture: does not require direct fixation in most cases β the fibula will heal with conservative management once the ankle is stabilised; only fix proximally if there is significant displacement threatening neurovascular structures or peroneal nerve
Peroneal nerve at risk with proximal fibula fracture β assess pre- and postoperatively; immediate neurolysis if nerve is compressed
Posterior malleolus (>25% articular surface or unstable): requires ORIF β posterolateral approach; fixes the PITFL attachment and stabilises the syndesmosis posteriorly
Postoperative Management & Complications
Non-weight bearing in below-knee cast for 6β8 weeks; progressive weight bearing thereafter
Syndesmotic screw: remove at 8β12 weeks before full weight bearing to prevent screw breakage β or leave if asymptomatic (debate exists)
Suture button: no removal required; allows progressive weight bearing earlier in some protocols
Complications: syndesmotic malreduction (most critical β leads to ankle incongruity and early arthritis); implant breakage; loss of reduction; post-traumatic ankle arthritis; chronic syndesmotic instability if undertreated
Syndesmotic malreduction is the most preventable and most consequential complication β intraoperative CT or fluoroscopic assessment of reduction is strongly recommended
Peroneal nerve palsy: common with proximal fibula fractures; most recover spontaneously over 3β6 months; EMG/NCS at 6 weeks if no recovery
Consultant-Level Considerations
Syndesmotic reduction accuracy: multiple studies demonstrate that up to 30β50% of syndesmotic reductions assessed as adequate on fluoroscopy are malreduced on CT β intraoperative CT or post-reduction CT is increasingly recommended as the standard of care
Fibula must be reduced into the incisura fibularis β external rotation, shortening, or posterior displacement of the fibula are common malreduction patterns; each changes ankle kinematics and leads to early arthritis
Deltoid repair debate: recent RCT data (REFIX trial and others) suggests that deltoid ligament repair in the setting of syndesmotic fixation improves medial stability and functional outcomes β repair is increasingly recommended in Maisonneuve injuries with deltoid disruption
Suture button vs screw: multiple RCTs now support suture button as equivalent or superior to screw fixation β allows physiological tibiofibular motion, avoids obligate screw removal, and may reduce malreduction rate due to dynamic self-correction
Chronic syndesmotic instability: missed Maisonneuve fracture leads to chronic ankle instability, pain, and progressive arthritis; late reconstruction with ligament repair and bony realignment is complex; emphasis on not missing the diagnosis acutely
Exam Pearls
Always palpate the entire fibula in any ankle injury β proximal tenderness = Maisonneuve until proven otherwise
Maisonneuve = PER pattern = medial injury first, then interosseous membrane tear propagating proximally to proximal fibula fracture
Medial clear space >4 mm = ankle instability; tibiofibular overlap <10 mm AP = syndesmosis widened
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References
Maisonneuve JGF. Recherches sur la fracture du perone. Arch Gen Med. 1840;7:165β187.
Lauge-Hansen N. Fractures of the ankle: combined experimental-surgical and experimental-roentgenologic investigations. Arch Surg. 1950;60(5):957β985.
Dikos GD et al. Normal tibiofibular relationships at the syndesmosis on axial CT imaging. J Orthop Trauma. 2012.
Gardner MJ et al. Intraoperative and postoperative CT confirms accurate reduction of transosseous suture button fixation for ankle syndesmosis injuries. J Orthop Trauma. 2012.
Kortekangas T et al. Suture button versus syndesmotic screw fixation for ankle syndesmosis injuries: randomised controlled trial. BMJ. 2019;367:l6725.
Sagi HC et al. Syndesmotic fixation with a TightRope device. Foot Ankle Int. 2012.
Wagener ML et al. The deltoid ligament in ankle fractures β repair or not? Injury. 2015.
Campbells Operative Orthopaedics. 14th Edition. Elsevier.
Rockwood and Greens Fractures in Adults. 9th Edition.
Orthobullets β Maisonneuve Fracture, Syndesmotic Injuries.
AO Surgery Reference β Ankle Fractures, Syndesmosis.