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Evidence Search

Search reputable indexed orthopaedic literature from multiple scholarly sources, classify the evidence, and link papers directly to wiki topics and cases.

Sources: PubMed, Europe PMC, Crossref

Linking results to Wiki: Periprosthetic Joint Infection — Principles
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Results are classified automatically from source metadata across PubMed, Europe PMC, and Crossref.
PubMed Crossref
PubMed Randomized Controlled Trial Evidence High

Reverse shoulder arthroplasty or nothing for patients with displaced proximal humeral fractures: a randomized controlled trial.

Journal of shoulder and elbow surgery | 2024 | Miquel J, Cassart E, Santana F, Martínez R

[Indexed for MEDLINE] 10. Int Orthop. 2025 Jul;49(7):1565-1570. doi: 10.1007/s00264-025-06537-w. Epub 2025 Apr 29. Alterations in coagulation profile of patients with periprosthetic joint infections. Saraiva ACM(1), Mozella AP(2)(3), Cobra HAAB(2), Sandes Kimura O(4), Guimarães JAM(5), Defino H(6), Leal AC(7). Author information: (1)Orthopaedic Department, Federal University of...

PubMed Guideline / Consensus Evidence High

The Diagnosis and Treatment of Acetabular Bone Loss in Revision Hip Arthroplasty: An International Consensus Symposium.

HSS journal : the musculoskeletal journal of Hospital for Special Surgery | 2022 | Sculco PK, Wright T, Malahias MA, Gu A

Conflict of interest statement: Declaration of Conflicting Interests: The author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: Peter K. Sculco, MD, reports relationships with EOS Imaging, DePuy Synthes, Intellijoint Surgical, and Parvizi Surgical Innovation. Timothy Wright, PhD, reports re...

PubMed Systematic Review / Meta-analysis Evidence High

Systematic review of single stage revision for prosthetic joint infection.

World journal of orthopedics | 2020 | Lum ZC, Holland CT, Meehan JP

Conflict of interest statement: Conflict-of-interest statement: Authors declare no conflict of interests for this article. 14. J Shoulder Elbow Surg. 2015 Mar;24(3):491-500. doi: 10.1016/j.jse.2014.10.005. Epub 2014 Dec 2. Preoperative and intraoperative infection workup in apparently aseptic revision shoulder arthroplasty. Updegrove GF(1), Armstrong AD(1), Kim HM(2). Author in...

PubMed Narrative Review Evidence Moderate

Optimizing Antibiotic Therapy in Musculoskeletal Infections.

Infectious disease clinics of North America | 2025 | Cortés-Penfield NW, Justo JA, McCreary EK, Ryder JH

[Indexed for MEDLINE] 3. Int Orthop. 2025 Jun;49(6):1309-1317. doi: 10.1007/s00264-025-06513-4. Epub 2025 Apr 4. Body mass index matters: morbid obese patients have different microorganism profiles in the setting of periprosthetic hip joint infections. Budin M(1)(2), Sandiford NA(3), Gehrke T(1), Citak M(4). Author information: (1)Helios Endo-Klinik Hamburg, Hamburg, Germany. (...

PubMed Narrative Review Evidence Moderate

Patient Preoperative Optimization: How to Do It and How to Be Paid for the Work.

The Journal of arthroplasty | 2025 | Clarke ZH, Springer BD, Sporer SM, Ast MP

[Indexed for MEDLINE] 18. HSS J. 2022 Feb;18(1):8-41. doi: 10.1177/15563316211034850. Epub 2021 Sep 28. The Diagnosis and Treatment of Acetabular Bone Loss in Revision Hip Arthroplasty: An International Consensus Symposium. Sculco PK(1), Wright T(1), Malahias MA(1), Gu A(2), Bostrom M(1), Haddad F(3), Jerabek S(1), Bolognesi M(4), Fehring T(5), Gonzalez DellaValle A(1), Jiranek...

PubMed Narrative Review Evidence Moderate

Antimicrobial Regimens in Cement Spacers for Periprosthetic Joint Infections: A Critical Review.

Antibiotics (Basel, Switzerland) | 2024 | Naoum S, Koutserimpas C, Pantekidis I, Giovanoulis V

Conflict of interest statement: The authors declare no conflicts of interest. 16. Front Microbiol. 2019 Jul 17;10:1602. doi: 10.3389/fmicb.2019.01602. eCollection 2019. Interaction Between Staphylococcal Biofilm and Bone: How Does the Presence of Biofilm Promote Prosthesis Loosening? Josse J(1)(2)(3), Valour F(1)(2)(3)(4), Maali Y(1)(2), Diot A(1)(2), Batailler C(2)(3)(5), Ferr...

PubMed Narrative Review Evidence Moderate

Shoulder Periprosthetic Joint Infection: Principles of Prevention, Diagnosis, and Treatment.

The Journal of bone and joint surgery. American volume | 2024 | Nazzal EM, Herman ZJ, Como M, Kaarre J

[Indexed for MEDLINE] Conflict of interest statement: Disclosure: The Disclosure of Potential Conflicts of Interest forms are provided with the online version of the article ( http://links.lww.com/JBJS/I242 ). 20. Cureus. 2019 Mar 26;11(3):e4325. doi: 10.7759/cureus.4325. Mycobacterium tuberculosis as a Cause of Periprosthetic Joint Infection After Total Knee Arthroplasty: A Re...

PubMed Narrative Review Evidence Moderate

Management of soft tissues in patients with periprosthetic joint infection.

Arthroplasty (London, England) | 2023 | Shao H, Zhou Y

Conflict of interest statement: None. 8. Arthroplasty. 2023 Apr 6;5(1):16. doi: 10.1186/s42836-023-00170-x. Principles of mechanical and chemical debridement with implant retention. Deckey DG(1), Christopher ZK(1), Bingham JS(1), Spangehl MJ(2). Author information: (1)Department of Orthopaedic Surgery, Mayo Clinic, Phoenix, AZ, 85054, USA. (2)Department of Orthopaedic Surgery,...

PubMed Narrative Review Evidence Moderate

Principles of mechanical and chemical debridement with implant retention.

Arthroplasty (London, England) | 2023 | Deckey DG, Christopher ZK, Bingham JS, Spangehl MJ

Conflict of interest statement: The authors declare that they have no competing interests. 9. J Shoulder Elbow Surg. 2024 Oct;33(10):2187-2195. doi: 10.1016/j.jse.2024.02.023. Epub 2024 Mar 26. Reverse shoulder arthroplasty or nothing for patients with displaced proximal humeral fractures: a randomized controlled trial. Miquel J(1), Cassart E(2), Santana F(3), Martínez R(4), Va...

PubMed Narrative Review Evidence Moderate

[Fracture-related infections after intramedullary nailing : Diagnostics and treatment].

Der Unfallchirurg | 2022 | Rupp M, Bärtl S, Lang S, Walter N

[Indexed for MEDLINE] 12. Orthop Traumatol Surg Res. 2020 Feb;106(1S):S27-S34. doi: 10.1016/j.otsr.2019.05.020. Epub 2019 Dec 5. Specificities of total hip and knee arthroplasty revision for infection. Jenny JY(1). Author information: (1)Pôle Locomax, hôpitaux universitaires de Strasbourg, 1, avenue Molière, 67200 Strasbourg, France. Electronic address: jean-yves.jenny@chru-str...

PubMed Narrative Review Evidence Moderate

Fracture-related infection: current methods for prevention and treatment.

Expert review of anti-infective therapy | 2020 | Foster AL, Moriarty TF, Trampuz A, Jaiprakash A

[Indexed for MEDLINE] 6. Bull Hosp Jt Dis (2013). 2018 Mar;76(1):55-61. Strategies for Management of Periprosthetic Joint Infection. Riesgo AM, Liporace FA. Periprosthetic joint infection (PJI) is one of the most catastrophic and difficult to manage complications following total hip and total knee arthroplasty. As the number of total joint arthroplasties continues to increase,...

PubMed Narrative Review Evidence Moderate

Specificities of total hip and knee arthroplasty revision for infection.

Orthopaedics & traumatology, surgery & research : OTSR | 2020 | Jenny JY

[Indexed for MEDLINE] 13. World J Orthop. 2020 Dec 18;11(12):559-572. doi: 10.5312/wjo.v11.i12.559. eCollection 2020 Dec 18. Systematic review of single stage revision for prosthetic joint infection. Lum ZC(1), Holland CT(2), Meehan JP(3). Author information: (1)Department of Orthopaedic Surgery, Davis Medical Center, University of California, Sacramento, CA 95817, United State...

PubMed Narrative Review Evidence Moderate

Interaction Between Staphylococcal Biofilm and Bone: How Does the Presence of Biofilm Promote Prosthesis Loosening?

Frontiers in microbiology | 2019 | Josse J, Valour F, Maali Y, Diot A

17. J Arthroplasty. 2025 Sep;40(9S1):S66-S71. doi: 10.1016/j.arth.2025.04.040. Epub 2025 Apr 19. Patient Preoperative Optimization: How to Do It and How to Be Paid for the Work. Clarke ZH(1), Springer BD(2), Sporer SM(3), Ast MP(4), Chen AF(5), Fricka KB(1). Author information: (1)Anderson Orthopedic Research Institute, Alexandria, Virginia. (2)Department of Orthopedic Surgery...

PubMed Narrative Review Evidence Moderate

Strategies for Management of Periprosthetic Joint Infection.

Bulletin of the Hospital for Joint Disease (2013) | 2018 | Riesgo AM, Liporace FA

[Indexed for MEDLINE] 7. Arthroplasty. 2023 Oct 3;5(1):52. doi: 10.1186/s42836-023-00205-3. Management of soft tissues in patients with periprosthetic joint infection. Shao H(1), Zhou Y(2). Author information: (1)Department of Orthopaedic Surgery, Beijing Jishuitan Hospital, Capital Medical University, Fourth Clinical College of Peking University, No. 31 Xinjiekou East Street,...

PubMed Narrative Review Evidence Moderate

Management of Prosthetic Joint Infection.

Infectious disease clinics of North America | 2017 | Tande AJ, Gomez-Urena EO, Berbari EF, Osmon DR

[Indexed for MEDLINE] 5. Expert Rev Anti Infect Ther. 2020 Apr;18(4):307-321. doi: 10.1080/14787210.2020.1729740. Epub 2020 Feb 19. Fracture-related infection: current methods for prevention and treatment. Foster AL(1)(2)(3)(4), Moriarty TF(1), Trampuz A(5), Jaiprakash A(2), Burch MA(1), Crawford R(2), Paterson DL(6), Metsemakers WJ(7)(8), Schuetz M(2)(3)(4), Richards RG(1). Au...

PubMed Narrative Review Evidence Moderate

Preoperative and intraoperative infection workup in apparently aseptic revision shoulder arthroplasty.

Journal of shoulder and elbow surgery | 2015 | Updegrove GF, Armstrong AD, Kim HM

[Indexed for MEDLINE] 15. Antibiotics (Basel). 2024 Aug 15;13(8):772. doi: 10.3390/antibiotics13080772. Antimicrobial Regimens in Cement Spacers for Periprosthetic Joint Infections: A Critical Review. Naoum S(1), Koutserimpas C(2)(3), Pantekidis I(4), Giovanoulis V(5), Veizi E(6), Piagkou M(3), Ioannou P(7), Samonis G(7)(8), Domouchtsidou A(9), Tsantes AG(9)(10), Papadopoulos D...

PubMed Original Article Evidence Unclassified

Body mass index matters: morbid obese patients have different microorganism profiles in the setting of periprosthetic hip joint infections.

International orthopaedics | 2025 | Budin M, Sandiford NA, Gehrke T, Citak M

[Indexed for MEDLINE] Conflict of interest statement: Declarations. Ethical approval: This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by an ethical committee (EK number blinded for submission). Consent to participate: Informed consent was obtained from all individual participants included in the study. Consent to publish...

PubMed Original Article Evidence Unclassified

Alterations in coagulation profile of patients with periprosthetic joint infections.

International orthopaedics | 2025 | Saraiva ACM, Mozella AP, Cobra HAAB, Sandes Kimura O

[Indexed for MEDLINE] Conflict of interest statement: Declarations. Ethical approval: This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committee of National Institute of Orthopedics and Traumatology - Brazil (Date: January 30th, 2021/No: 40830020.5.0000.5273). Consent to participate: Informed consent was obt...

Crossref Journal Article Evidence Unclassified

Case Reports: Periprosthetic Joint Infection after Total Joint Arthroplasty Following Swimming Activity

Journal of Orthopaedic Case Reports | 2024 | Aviram Albagly, Ariel D Levine, Oren Ben-Lulu

Introduction: Periprosthetic joint infection (PJI) is a severe complication of total joint arthroplasty (TJA), occurring in approximately 1–2% of primary procedures. These infections, characterized by an overall weighted mean incidence of 0.97% for total hip arthroplasty (THA) and 1.03% for total knee arthroplasty (TKA), pose significant challenges for patients and health-care...

Crossref Scholarly Work Evidence Unclassified

7 Management of Periprosthetic Joint Infection

Management of Orthopaedic Infections | 2021

Periprosthetic joint infection (PJI) continues to be a devastating problem in the field of total joint arthroplasty. There are a number of surgical options to decide from and management decisions are based upon the interplay between host, pathogen, and surgeon characteristics. The goal of management is to maximize function, prevent systemic complications, and eradicate infectio...

PubMed Original Article Evidence Unclassified

General treatment principles for fracture-related infection: recommendations from an international expert group.

Archives of orthopaedic and trauma surgery | 2020 | Metsemakers WJ, Morgenstern M, Senneville E, Borens O

[Indexed for MEDLINE] Conflict of interest statement: All authors declare no conflict of interest with respect to the preparation and writing of this article. 2. Infect Dis Clin North Am. 2025 Sep;39(3):361-382. doi: 10.1016/j.idc.2025.02.009. Epub 2025 Apr 11. Optimizing Antibiotic Therapy in Musculoskeletal Infections. Cortés-Penfield NW(1), Justo JA(2), McCreary EK(3), Ryder...

Crossref Journal Article Evidence Unclassified

Modulating antibiotic release from reservoirs in 3D‐printed orthopedic devices to treat periprosthetic joint infection

Journal of Orthopaedic Research | 2020 | Brian Allen, Christina Moore, Thorsten Seyler, Ken Gall

AbstractPeriprosthetic joint infection is a costly debilitating affliction following total joint arthroplasty. Despite a relatively low incidence rate, periprosthetic joint infection is an increasing problem due to a substantial increase in arthroplasty surgeries over time. The current treatment is replacing the primary implant with a temporary bone cement spacer that releases...

Crossref Journal Article Evidence Unclassified

Forced-air warming discontinued: periprosthetic joint infection rates drop

Orthopedic Reviews | 2017 | Scott D. Augustine

Several studies have shown that the waste heat from forced-air warming (FAW) escapes near the floor and warms the contaminated air resident near the floor. The waste heat then forms into convection currents that rise up and contaminate the sterile field above the surgical table. It has been shown that a single airborne bacterium can cause a periprosthetic joint infection (PJI)...